Adipogen/Malformin C/AG-CN2-0107-C250/250 µg
商品编号：
AG-CN2-0107-C250
品牌：
Adipogen Inc
市场价：
¥2200.00
美元价：
1320.00
产品分类：
其他试剂
公司分类：
Other_reagents
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
| ProductDetails | |
|---|---|
| Synonyms | 5-L-Leucine-MalforminA;BRN4896114;(-)-cyclo[D-Cys(1)-D-Cys(1)-L-Val-D-Leu-L-Leu-] |
| ProductType | Chemical |
| Properties | |
| Formula | C23H39N5O5S2 |
| MW | 529.7 |
| CAS | 59926-78-2 |
| Source/HostChemicals | Synthetic.OriginallyisolatedfromAspergillusnigerFKI-2342. |
| PurityChemicals | ≥95%(HPLC) |
| Appearance | Whitesolid. |
| Solubility | SolubleinDMSO,methanol,ethanolorchloroform.Insolubleinwater. |
| Declaration | SynthesizedbytheOrganicChemistryGroupofTheKitasatoInstitute. |
| OtherProductData | MalforminCisabicyclicpentapeptidecontainingL-leucine,D-isoleucine,L-valine,andtwoD-cysteinescoupledwithadisulfide-bondbridge.MalforminsA1andC,originallyisolatedfromtheculturebrothofAspergillusnigerFKI-2342,werefoundtoabrogatethebleomycin-inducedG2arrestinJurkatcellswithIC50valuesof480nMand0.9nM,respectively.Malforminsmaybepromisingcandidatesasanti-canceragents. |
| InChiKey | TZODYIWCRGWHQB-TZNCUMHOSA-N |
| ShippingandHandling | |
| Shipping | AMBIENT |
| ShortTermStorage | +4°C |
| LongTermStorage | -20°C |
| Use/StABIlity | Stableforatleast3yearsafterreceiptwhenstoredat-20°C. |
| Documents | |
| MSDS |  DownloadPDF |
| ProductSpecificationSheet | |
| Datasheet | DownloadPDF |
- Peptideantibiotic[1].
- Inducesrootcurvatureandmalformationinplants[1].
- Antibacterial[1,2],antimalarialandantitrypanosomal[4].
- DisruptsthecellcycleattheG2checkpointofcancercells,leADIngtosensitizationofthecancercellstoanti-cancerreagents[3].
ProductReferences
- MalforminC,anewmetaboliteofAspergillusniger:R.J.Anderegg,etal.;JACS98,3365(1976)
- ProductionandantibacterialactivityofmalformingC,atoxicmetaboliteofAspergillusniger:B.Kobbe,etal.;Appl.Environ.Microbiol.33,996(1977)
- Fungalmalforminsinhibitbleomycin-inducedG2checkpointinJurkatcells:K.Hagimori,etal.;Biol.Pharm.Bull.30,1379(2007)
- Solid-phasesynthesisandBIOLOGicalactivityofmalforminCanditsderivatives:Y.Kojima,etal.;J.Antibiot.(Tokyo)62,681(2009)
品牌介绍
Adipogen公司由三个子公司组成，分别是Adipogen,Inc.(韩国),AdipogenSA(瑞士)和 AdipogenCorporation(美国圣地亚哥)。总部设在美国，运营总部在瑞士利斯塔尔。Adipogen公司专门从事生命科学研究试剂的开发，如癌症、免疫、炎症、代谢疾病（糖尿病、肥胖）、干细胞和神经退行性疾病等领域。其重点关注开发创新优质的ELISA试剂盒。另外，也可提供抗体和蛋白产品，Adipogen拥有自己的化学实验室，致力于开发创新型小分子化合物。
联络我们
