Adipogen/Makisterone A/AG-CN2-0073-M001/1 mg
商品编号：
AG-CN2-0073-M001
品牌：
Adipogen Inc
市场价：
¥2000.00
美元价：
1200.00
产品分类：
其他试剂
公司分类：
Other_reagents
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
| ProductDetails | |
|---|---|
| Synonyms | 2β,3β,14α,20R,22R,25-Hexahydroxy-5β-24R-ergost-7-en-6-one |
| ProductType | Chemical |
| Properties | |
| Formula | C28H46O7 |
| MW | 494.7 |
| CAS | 20137-14-8 |
| Source/HostChemicals | IsolatedfromIpomoeahederacea. |
| PurityChemicals | ≥95%(HPLC) |
| Appearance | Whitetooff-whitesolid. |
| Solubility | Solubleinaceticacid,ethanol,methanolorDMSO.Sparinglysolubleinchloroform.Insolubleinwater. |
| Identity | Identitydeterminedby1H-NMR. |
| InChiKey | IJRBORPEVKCEQD-WJUVRXFPSA-N |
| ShippingandHandling | |
| Shipping | AMBIENT |
| ShortTermStorage | +4°C |
| LongTermStorage | -20°C |
| Use/StABIlity | Stableforatleast2yearsafterreceiptwhenstoredat-20°C. |
| Documents | |
| MSDS |  DownloadPDF |
| ProductSpecificationSheet | |
| Datasheet | DownloadPDF |
- Amemberoftheecdysteroidfamily.
- Ecdysonereceptor(EcR)agoNIST.
- Inducestheexpressionofgenescodingforproteinsthatthelarvarequires,anditcauseschromosomepuffs(sitesofhighexpression)toforminpolytenechromosomes.
- Playsaroleininsectdevelopment,cellproliferaton,growthandapoptosisbycontrollinggeneexpressioninvolvedinmoultingandmetamorphosis.Itactsthroughaheterodimericreceptorcomprisingtheecdysonereceptorandtheultraspiracleproteins(USP).
- Appearsinplantsmostlyasaprotectionagent(toxinsorantifeedants)againstherbivorousinsects.
- Couldbeusedforcontrolledgeneexpressioninscientificresearch,agricultureandmedicine.
- Couldbeusedforthedevelopmentofselectiveinsectgrowthregulatorsforuseasenvironmentallybenigninsecticides.
ProductReferences
- Paperchromatographicseparationofalpha-ecdysone,ecdysterone,inokosterone,makisteroneAandponasteroneA:M.W.Gilgan&T.E.Farquharson;Steroids22,365(1973)
- ThedeterminationofabsoluteconfigurationatC-24ofthephytoecdysonemakisteroneA:B.Danieli,etal.;J.C.S.Chem.Commun.745(1974)
- MakisteroneA:a28-carbonhexahydroxymoltinghormonefromtheembryoofthemilkweedbug:J.N.Kaplanis,etal.;Science190,681(1975)
- EvidenceforthepresenceofmakisteroneAinDrosophilalarvaeandthesecretionof20-deoxymakisteroneAbytheringgland:C.P.Redfern;PNAS81,5643(1984)
- Ecdysteroidsincreasetheyieldofrecombinantproteinproducedinbaculovirusinsectcellexpressionsystem:M.Sarvari,etal.;BBRC167,1154(1990)
- TheeffectsofseveralecdysteroidsandecdysteroidagonistsontwoDrosophilaimaginaldisccelllines:D.M.Cottam&M.J.Milner;CellMol.LifeSci.53,600(1997)
- EcdysonereceptorsandtheirBIOLOGicalactions:L.M.Riddiford,etal.;Vitam.Horm.60,1(2000)
- Ecdysteroidsofquinoaseeds(ChenopodiumquinoaWilld.):N.Zhu,etal.;J.Agric.FoodChem.49,2576(2001)
- DNAsynthesisintheimaginalwingdiscsoftheAmericanbollwormHelicoverpaarmigera(Hübner):A.Josephrajkumar&B.Subrahmanyam; J.Biosci.27,113(2002)
- Ecdysone-regulatedpuffgenes2000:C.S.Thummel;InsectBiochem.Mol.Biol.32,113(2002)
- Ecdysone-controlledexpressionoftransgenes:L.D.Graham;ExpertOpin.Biol.Ther.2,525(2002)
- Non-genomicecdysoneeffectsandtheinvertebratenuclearsteroidhormonereceptorEcR-newroleforan"old"receptor?U.Schlattner,etal.;Mol.CellEndocrinol.247,64(2006)
品牌介绍
Adipogen公司由三个子公司组成，分别是Adipogen,Inc.(韩国),AdipogenSA(瑞士)和 AdipogenCorporation(美国圣地亚哥)。总部设在美国，运营总部在瑞士利斯塔尔。Adipogen公司专门从事生命科学研究试剂的开发，如癌症、免疫、炎症、代谢疾病（糖尿病、肥胖）、干细胞和神经退行性疾病等领域。其重点关注开发创新优质的ELISA试剂盒。另外，也可提供抗体和蛋白产品，Adipogen拥有自己的化学实验室，致力于开发创新型小分子化合物。
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