Adipogen/Linifanib/SYN-1002-M010/10 mg
商品编号：
SYN-1002-M010
品牌：
Adipogen Inc
市场价：
¥4320.00
美元价：
2592.00
产品分类：
其他试剂
公司分类：
Other_reagents
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
| ProductDetails | |
|---|---|
| Synonyms | ABT-869;AL39324;RG-3635 |
| ProductType | Chemical |
| Properties | |
| Formula | C21H18FN5O |
| MW | 375.4 |
| CAS | 796967-16-3 |
| PurityChemicals | ≥95% |
| Appearance | Solid. |
| Solubility | SolubleinDMSOorethanol. |
| Declaration | ManufacturedbySynKinase. |
| OtherProductData | Target:PDGFR|KinaseGroup:RTK|Substrate:Tyrosine ClickhereforOriginalManufacturerProductDatasheet Ourproductdescriptionmaydifferslightlyfromtheoriginalmanufacturersproductdatasheet. |
| InChiKey | MPVGZUGXCQEXTM-UHFFFAOYSA-N |
| ShippingandHandling | |
| Shipping | AMBIENT |
| ShortTermStorage | +4°C |
| LongTermStorage | -20°C |
| Use/StABIlity | Stableforatleast2yearsafterreceiptwhenstoredat-20°C. |
| Documents | |
| MSDS |  DownloadPDF |
| ProductSpecificationSheet | |
| Datasheet | DownloadPDF |
Linifanib(A741439;A-741439;A741439;ABT-869;ABT869;RG3635)isanorallyactivemulti-targetedreceptortyrosinekinaseinhibitorforthetreatmentofvariouscancers.Thecompoundisdesignedtoinhibitvascularendothelialgrowthfactorandplatelet-derivedgrowthfactorreceptorsandisamultitargetedtyrosinekinasereceptorinhibitorthatsuppressesFLT3signaling.ItisinphaseIIIdevelopmentforlivercancerandphaseIIdevelopmentfornon-smallcelllungcancer,breastcancer,andcolorectalcancer.RecentresearchalsoindicatesthatLinifanibinhibitsproliferationandinducesapoptosisinAMLpatientcellsviareductionofAKTandGSK3βphosphorylationandmaybeinfluencialinAMLtherapy.
ProductReferences
- DiscoveryofN-(4-(3-amino-1H-indazol-4-yl)phenyl)-N"-(2-fluoro-5-methylphenyl)urea(ABT-869),a3-aminoindazole-basedorallyactivemultitargetedreceptortyrosinekinaseinhibitor:Y.Dai,etal.;J.Med.Chem.50,1584(2007)
品牌介绍
Adipogen公司由三个子公司组成，分别是Adipogen,Inc.(韩国),AdipogenSA(瑞士)和 AdipogenCorporation(美国圣地亚哥)。总部设在美国，运营总部在瑞士利斯塔尔。Adipogen公司专门从事生命科学研究试剂的开发，如癌症、免疫、炎症、代谢疾病（糖尿病、肥胖）、干细胞和神经退行性疾病等领域。其重点关注开发创新优质的ELISA试剂盒。另外，也可提供抗体和蛋白产品，Adipogen拥有自己的化学实验室，致力于开发创新型小分子化合物。
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