Adipogen/Latrunculin A/AG-CN2-0027-C500/500 µg
商品编号：
AG-CN2-0027-C500
品牌：
Adipogen Inc
市场价：
¥7800.00
美元价：
4680.00
产品分类：
其他试剂
公司分类：
Other_reagents
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
| ProductDetails | |
|---|---|
| Synonyms | LAT-A;NSC613011 |
| ProductType | Chemical |
| Properties | |
| Formula | C22H31NO5S |
| MW | 421.6 |
| MerckIndex | 14:5378 |
| CAS | 76343-93-6 |
| Source/HostChemicals | IsolatedfromLatrunculiamagnifica. |
| PurityChemicals | ≥97%(HPLC) |
| Appearance | Whitetolightyellowsolid. |
| Solubility | SolubleinDMSOorethanol. |
| InChiKey | DDVBPZROPPMBLW-IZGXTMSKSA-N |
| ShippingandHandling | |
| Shipping | AMBIENT |
| ShortTermStorage | +4°C |
| LongTermStorage | -20°C |
| HandlingAdvice | Protectfromlight. |
| Use/StABIlity | Stableforatleast2yearsafterreceiptwhenstoredat-20°C. Storesolutionsat-20°Cinthedark. |
| Documents | |
| MSDS |  DownloadPDF |
| ProductSpecificationSheet | |
| Datasheet | DownloadPDF |
- Cellpermeablemarinetoxin[1].
- DisruptsMICROFILament-mediatedprocesses[2].
- Actinpolymerizationinhibitorinvitroandinvivobytheformationofa1:1complexwithmonomericG-actin[1,2,3,6].
- Depolymerizesactinfilaments(F-actin)[3].
- Potentphagocytosisinhibitor[4].
- Anticancercompound[7,8].Suppresseshypoxia-inducedHIF-1activationintumorcells[7].Inhibitstumorcellinvasion[7].
- Actsviaadifferentmechanismthancytochalasins.
ProductReferences
- Latrunculins:novelmarinetoxinsthatdisruptmicrofilamentorganizationinculturedcells:I.Spector,etal.;Science219,493(1983)
- Latrunculininhibitsthemicrofilament-mediatedprocessesduringfertilization,cleavageandearlydevelopmentinseaurchinsandmice:G.Schatten,etal.;Exp.CellRes.166,191(1986)
- Inhibitionofactinpolymerizationbylatrunculin:A:M.Coue,etal.;FEBSLett.213,316(1987)
- LatrunculinAisapotentinhibitorofphagocytosisbymacrophages:C.A.deOliveira&B.Mantovani;LifeSci.43,1825(1988)
- Latrunculins-novelmarinemacrolidesthatdisruptmicrofilamentorganizationandaffectcellgrowth:I.ComparisonwithcytochalasinD:I.Spector,etal.;CellMotil.Cytoskeleton13,127(1989)
- Actin-latrunculinAstructureandfunction.Differentialmodulationofactin-bindingproteinfunctionbylatrunculinA:E.G.Yarmola,etal.;J.Biol.Chem.275,28120(2000)
- LatrunculinAanditsC-17-O-carbamatesinhibitprostatetumorcellinvasionandHIF-1activationinbreasttumorcells:K.A.Sayed,etal.;J.Nat.Prod.71,396(2008)
- Latrunculinahasastronganticancereffectinaperitonealdisseminationmodelofhumangastriccancerinmice:H.Konishi,etal.;AnticancerRes.29,2091(2009)
- Nucleolarasymmetryandtheimportanceofseptinintegrityuponcellcyclearrest:U.Rai,etal.;PLoSONE12,e0174306(2017)
品牌介绍
Adipogen公司由三个子公司组成，分别是Adipogen,Inc.(韩国),AdipogenSA(瑞士)和 AdipogenCorporation(美国圣地亚哥)。总部设在美国，运营总部在瑞士利斯塔尔。Adipogen公司专门从事生命科学研究试剂的开发，如癌症、免疫、炎症、代谢疾病（糖尿病、肥胖）、干细胞和神经退行性疾病等领域。其重点关注开发创新优质的ELISA试剂盒。另外，也可提供抗体和蛋白产品，Adipogen拥有自己的化学实验室，致力于开发创新型小分子化合物。
联络我们
