Adipogen/KU-55933/SYN-1051-M050/50 mg
商品编号：
SYN-1051-M050
品牌：
Adipogen Inc
市场价：
¥7780.00
美元价：
4668.00
产品分类：
其他试剂
公司分类：
Other_reagents
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
| ProductDetails | |
|---|---|
| Synonyms | KU55933 |
| ProductType | Chemical |
| Properties | |
| Formula | C21H17NO3S2 |
| MW | 395.5 |
| CAS | 587871-26-9 |
| PurityChemicals | ≥95% |
| Appearance | Solid. |
| Solubility | SolubleinDMSOorethanol. |
| Declaration | ManufacturedbySynKinase. |
| OtherProductData | Target:ATM/ATR|KinaseGroup:Atypical(PIKK)|Substrate:Serine-Threonine ClickhereforOriginalManufacturerProductDatasheet Ourproductdescriptionmaydifferslightlyfromtheoriginalmanufacturersproductdatasheet. |
| InChiKey | XRKYMMUGXMWDAO-UHFFFAOYSA-N |
| ShippingandHandling | |
| Shipping | AMBIENT |
| ShortTermStorage | +4°C |
| LongTermStorage | -20°C |
| Use/StABIlity | Stableforatleast2yearsafterreceiptwhenstoredat-20°C. |
| Documents | |
| MSDS |  DownloadPDF |
| ProductSpecificationSheet | |
| Datasheet | DownloadPDF |
KU55933isapotentandselectiveATP-competitiveinhibitorofATM,withanIC(50)of13nMandaKiof2.2nM.KU55933haspotentialforuseasanewrADIo-andchemo-sensitizingagentforthetreatmentofcancer.
ProductReferences
- Identificationandcharacterizationofanovelandspecificinhibitoroftheataxia-telangiectasiamutatedkinaseATM:I.Hickson,etal.;CancerRes.64,9152(2004)
- Ataxia-telangiectasiamutatedkinaseregulatesribonucleotidereductaseandmitochondrialhomeostasis:J.S.Eaton|etal.;J.Clin.Invest.117,2723(2007)
- Ataxiatelangiectasiamutatedandp21CIP1modulatecellsurvivalofdrug-inducedsenescenttumorcells:implicationsforchemotherapy:E.Crescenzi,etal.;Clin.CancerRes.14,1877(2008)
品牌介绍
Adipogen公司由三个子公司组成，分别是Adipogen,Inc.(韩国),AdipogenSA(瑞士)和 AdipogenCorporation(美国圣地亚哥)。总部设在美国，运营总部在瑞士利斯塔尔。Adipogen公司专门从事生命科学研究试剂的开发，如癌症、免疫、炎症、代谢疾病（糖尿病、肥胖）、干细胞和神经退行性疾病等领域。其重点关注开发创新优质的ELISA试剂盒。另外，也可提供抗体和蛋白产品，Adipogen拥有自己的化学实验室，致力于开发创新型小分子化合物。
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