Adipogen/Kirromycin/BVT-0157-M005/5 mg
商品编号：
BVT-0157-M005
品牌：
Adipogen Inc
市场价：
¥10600.00
美元价：
6360.00
产品分类：
其他试剂
公司分类：
Other_reagents
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
| ProductDetails | |
|---|---|
| Synonyms | Mocimycin;Delvomycin;MYC8003;NSC316094 |
| ProductType | Chemical |
| Properties | |
| Formula | C43H60N2O12 |
| MW | 796.9 |
| MerckIndex | 14:6225 |
| CAS | 50935-71-2 |
| RTECS | QA2805000 |
| Source/HostChemicals | IsolatedfromStreptomycescollinus. |
| PurityChemicals | ≥96%(HPLC) |
| Appearance | Yellowpowder. |
| Solubility | SolubleinmethanolorDMSO. |
| Identity | Determinedby1H-NMRandUV. |
| InChiKey | HMSYAPGFKGSXAJ-PAHGNTJYSA-N |
| ShippingandHandling | |
| Shipping | AMBIENT |
| ShortTermStorage | +4°C |
| LongTermStorage | -20°C |
| Use/StABIlity | Stableforatleast1yearafterreceiptwhenstoredat-20°C. Storesolutionsat-20°Cinthedark. |
| Documents | |
| MSDS |  DownloadPDF |
| ProductSpecificationSheet | |
| Datasheet | DownloadPDF |
- Antibiotic.Memberoftheelfermycingroup.
- Antibacterial.
- Proteinbiosynthesisinhibitor.
- SpecificallyinteractswiththebacterialelongationfactorEF-TuandpreventsthereleaseofEF-TufromthebacterialribosomeafterGTPhydrolysis.IntheabsenceofribosomesitinducesEF-Tu-dependenthydrolysisofGTP.
- Animalgrowthpromoterusedinpoultrybreeding.
ProductReferences
- Metabolicproductsofmicroorganisms.99.Kirromycin:H.Wolf&H.Zähner;Arch.Mikrobiol.83,147(1972)
- Kirromycin,aninhibitorofthe30Sribosomalsubunitsfunction:H.Wolf,etal.;FEBSLett.21,347(1972)
- Thetotalstructureofthenovelantibioticmocimycin:C.Vos&P.E.J.Verwiel;TetrahedronLett.1973,5173(1973)
- Kirromycin,aninhibitoroftheproteinbiosynthesisthatactsonelongationfactorTu:H.Wolf,etal.;PNAS71,4910(1974)
- Mechanismoftheinhibitionofproteinsynthesisbykirromycin.RoleofelongationfactorTuandribosomes:H.Wolf,etal.;Eur.J.Biochem.75,67(1977)
- Actionofpulvomycinandkirromycinoneukaryoticcells:B.Schmid,etal.;FEBSLett.96,189(1978)
- EnergeticaspectsoftheEF-Tu-dependentGTPaseactivity.Astudyusingtheantibiotickirromycin:V.Bocchin,etal.;Eur.J.Biochem.113,53(1980)
- EffectsofelfamycinsonelongationfactorTufromEscherichiacoliandStaphylococcusaureus:C.C.Hall,etal.;Antimicrob.AgentsChemother.33,322(1989)
- InhibitorymechanismsofantibioticstargetingelongationfactorTu:T.Hogg,etal.;Curr.Prot.Pept.Sci.3,121(2002)
- ElongationfactorTu-targetedantibiotics:fourdifferentstructures,twomechanismsofaction:A.Parmeggiani&P.Nissen;FEBSLett.580,4576(2006)(Review)
- Molecularanalysisofthekirromycinbiosyntheticgenecluster:T.Weber,etal.;Chem.Biol.15,175(2008)
- GTPaseactivationofelongationfactorEF-Tubytheribosomeduringdecoding:J.-C.Schuette,etal.;EMBOJ.28,755(2009)
- Interactionofapicoplast-encodedelongationfactorEF-Tuwithnuclear-encodedEF-TsmediatestranslationinthePlasmodiumfalciparumplastid:S.Biswas,etal.;Intern.J.Parasitol.41,417(2011)
- ThephosphopantetheinyltransferasekirPactivatestheACPandPCPdomainsofthekirromycinNRPS/PKSofStreptomycescollinusTü365:M.Pavlidou,etal.;FEMSMicrobiol.Lett.319,26(2011)
品牌介绍
Adipogen公司由三个子公司组成，分别是Adipogen,Inc.(韩国),AdipogenSA(瑞士)和 AdipogenCorporation(美国圣地亚哥)。总部设在美国，运营总部在瑞士利斯塔尔。Adipogen公司专门从事生命科学研究试剂的开发，如癌症、免疫、炎症、代谢疾病（糖尿病、肥胖）、干细胞和神经退行性疾病等领域。其重点关注开发创新优质的ELISA试剂盒。另外，也可提供抗体和蛋白产品，Adipogen拥有自己的化学实验室，致力于开发创新型小分子化合物。
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