Adipogen/Jasplakinolide (high purity)/AG-CN2-0037-C050/50 µg
商品编号：
AG-CN2-0037-C050
品牌：
Adipogen Inc
市场价：
¥3400.00
美元价：
2040.00
产品分类：
其他试剂
公司分类：
Other_reagents
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
| ProductDetails | |
|---|---|
| Synonyms | Jaspamide;NSC613009 |
| ProductType | Chemical |
| Properties | |
| Formula | C36H45BrN4O6 |
| MW | 709.7 |
| CAS | 102396-24-7 |
| Source/HostChemicals | IsolatedfromJaspissplendens. |
| PurityChemicals | ≥98%(HPLC) |
| Appearance | Off-whitesolid. |
| Solubility | Solubleinethanol,methanolorDMSO. |
| Identity | DeterminedbyMS. |
| InChiKey | GQWYWHOHRVVHAP-DHKPLNAMSA-N |
| ShippingandHandling | |
| Shipping | AMBIENT |
| ShortTermStorage | +4°C |
| LongTermStorage | -20°C |
| HandlingAdvice | Protectfromlight. |
| Use/StABIlity | Stableforatleast2yearsafterreceiptwhenstoredat-20°C. |
| Documents | |
| MSDS |  DownloadPDF |
| ProductSpecificationSheet | |
| Datasheet | DownloadPDF |
- Cellpermeable,non-fluorescentF-actinprobe[3,8,12].
- Potentinducerofactinpolymerizationandstabilization[3,8,12].
- Competeswithphallotoxinsforactinbinding[3].
- Antifungalandantiparasiticcompound[1,2,9].
- Antiproliferativeandanticancercompound[3,4,5].
- Apoptosisenhancer/inducer[6,10].
- Toolusedforautophagy/phagocytosisresearch[7,11,13].
ProductReferences
- Jasplakinolide,acyclodepsipeptidefromthemarinesponge,Jaspissp:P.Crews,etal.;TetrahedronLett.27,2797(1986)
- Jaspamide,amodifiedpeptidefromaJaspissponge,withinsecticidalandantifungalactivity:T.M.Zabriskie,etal.;JACS108,3123(1986)
- Jasplakinolide,acytotoxicnaturalproduct,inducesactinpolymerizationandcompetitivelyinhibitsthebindingofphalloidintoF-actin:M.R.Bubb,etal.;J.Biol.Chem.269,14869(1994)
- Jasplakinolide"sinhibitionofthegrowthofprostatecarcinomacellsinvitrowithdisruptionoftheactinCytoskeleton:A.M.Senderowicz,etal.;J.Natl.CancerInst.87,46(1995)
- Growthmodulationanddifferentiationofacutemyeloidleukemiacellsbyjaspamide:I.Fabian,etal.;Exp.Hematol.23,583(1995)
- Actinstabilizationbyjasplakinolideenhancesapoptosisinducedbycytokinedeprivation:S.C.Posey&B.E.Bierer;J.Biol.Chem.274,4259(1999)
- Alterationofactinorganizationbyjaspamideinhibitsruffling,butnotphagocytosisoroxidativeburst,inHL-60cellsandhumanmonocytes:I.Fabian,etal.;Blood93,3994(1999)
- Jasplakinolide.Anactin-specificreagentthatpromotesactinpolymerization:A.Holzinger;MethodsMol.Biol.161,109(2001)(Review)
- Effectofjasplakinolideonthegrowth,invasion,andactincytoskeletonofPlasmodiumfalciparum:Y.Mizuno,etal.;Parasitol.Res.88,844(2002)
- InductionofapoptosisandCD10/neutralendopeptidaseexpressionbyjaspamideinHL-60linecells:D.P.Cioca&K.Kitano;Cell.Mol.LifeSci.59,1377(2002)
- ClearanceofaHiranobody-likeF-actinaggresomegeneratedbyjasplakinolide:F.Lázaro-Diéguez,etal.;Autophagy4,717(2008)
- Jasplakinolide:anactin-specificreagentthatpromotesactinpolymerization:A.Holzinger;MethodsMol.Biol.586,71(2009)(Review)
- Dynamicmacrophage"probing"isrequiredfortheefficientcaptureofphagocytictargets:R.S.Flannagan,etal.;J.CellBiol.191,1205(2010)
品牌介绍
Adipogen公司由三个子公司组成，分别是Adipogen,Inc.(韩国),AdipogenSA(瑞士)和 AdipogenCorporation(美国圣地亚哥)。总部设在美国，运营总部在瑞士利斯塔尔。Adipogen公司专门从事生命科学研究试剂的开发，如癌症、免疫、炎症、代谢疾病（糖尿病、肥胖）、干细胞和神经退行性疾病等领域。其重点关注开发创新优质的ELISA试剂盒。另外，也可提供抗体和蛋白产品，Adipogen拥有自己的化学实验室，致力于开发创新型小分子化合物。
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