Adipogen/Indo 1-AM/CDX-I0019-M001/1 mg
商品编号：
CDX-I0019-M001
品牌：
Adipogen Inc
市场价：
¥2820.00
美元价：
1692.00
产品分类：
其他试剂
公司分类：
Other_reagents
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
| ProductDetails | |
|---|---|
| Synonyms | Indo-1-(acetoxymethyl)ester;4-(6-Carboxy-2-indolyl)-4"-methyl-2,2"-(ethylenedioxy)dianiline-N,N,N",N"-tetraaceticacidtetrakis(acetoxymethyl)ester |
| ProductType | Chemical |
| Properties | |
| Formula | C47H51N3O22 |
| MW | 1009.93 |
| CAS | 112926-02-0 |
| Source/HostChemicals | Synthetic. |
| PurityChemicals | ≥90%(HPLC) |
| Appearance | Off-whitesolid. |
| Solubility | SolubleinDMSOormethanol. |
| Declaration | ManufacturedbyChemodex. |
| OtherProductData | ClickhereforOriginalManufacturerProductDatasheet Ourproductdescriptionmaydifferslightlyfromtheoriginalmanufacturersproductdatasheet. |
| InChiKey | CAWBRCOBJNWRLK-UHFFFAOYSA-N |
| ShippingandHandling | |
| Shipping | AMBIENT |
| ShortTermStorage | -20°C |
| LongTermStorage | -20°C |
| HandlingAdvice | Keepcoolanddry. Protectfromlightandmoisture. |
| Use/StABIlity | Stableforatleast2yearsafterreceiptwhenstoredat-20°C. |
| Documents | |
| MSDS | No |
| ProductSpecificationSheet | |
| Datasheet |  DownloadPDF |
INDO1-AMisapopularnon-invasiveUV-excitablecalciumindicator.Itisthecell-permeableesterderivativeofINDO1.Aftercrossingthecellmembrane,INDO1-AMisrapidlyhydrolyzedbycytoplasmicesterasestoproducetheratiometricfluorescentcalciumindicatorINDO1,whichremainstrappedwithinthecell.INDO1/AMhasbeenusedtoselectivelymonitorCa2+levelsinmitochondriaandinthecytosol.INDO1isidealforanalysesusingflowcytometry,asitusesasingleexcitationsource(usuallythe351-364nmspectrallinesoftheargon-ionlaser).IncontrasttoFURA1,INDO1hasadualemissionpeak.TheemissionofINDO1shiftsto400nm(whenboundtoCa2+)from480nminCa2+-freeenvironments.INDO1ispronetophotobleaching,whichlimitsitsusefulnessinmethodsinvolvingmicroscopy.CalciummeasurementiscriticalfornumerousBIOLOGicalinvestigations.FluorescentprobesthatshowspectralresponsesuponbindingCa2+haveenabledresearcherstoinvestigatechangesinintracellularfreeCa2+concentrationsbyusingfluorescencemicroscopy,flowcytometry,fluorescencespectroscopyandfluorescencemicroplatereaders.SpectralData:λex330nm;λem450nm(withCalcium),λex356nm;λem478nminmethanol.
ProductReferences
(1)G.Grynkiewicz,etal.;J.Biol.Chem.260,3440(1985)|(2)M.Lopez,etal.;Cytometry10,165(1989)|(3)J.P.Grierson,etal.;J.Neurophysiol.67,704(1992)|(4)E.J.Griffiths,etal.;Am.J.Physiol.273,C37(1997)|(5)R.M.Paredes,etal.;Meth.AComp.Meth.Enzymol.46,143(2008)|(6)Z.Zhou,etal.;J.Physiol.507,379(1998)|(7)S.Bailey&P.J.Macardle;J.Immunol.Meth.311,220(2006)|(8)A.Nelemans;MethodsMol.Biol.312,47(2006)|(9)R.W.Sabnis;Handbookofbiologicaldyesandstains(2010)
品牌介绍
Adipogen公司由三个子公司组成，分别是Adipogen,Inc.(韩国),AdipogenSA(瑞士)和 AdipogenCorporation(美国圣地亚哥)。总部设在美国，运营总部在瑞士利斯塔尔。Adipogen公司专门从事生命科学研究试剂的开发，如癌症、免疫、炎症、代谢疾病（糖尿病、肥胖）、干细胞和神经退行性疾病等领域。其重点关注开发创新优质的ELISA试剂盒。另外，也可提供抗体和蛋白产品，Adipogen拥有自己的化学实验室，致力于开发创新型小分子化合物。
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