Adipogen/Incensol acetate/AG-CN2-0484-M001/1 mg
商品编号：
AG-CN2-0484-M001
品牌：
Adipogen Inc
市场价：
¥2400.00
美元价：
1440.00
产品分类：
其他试剂
公司分类：
Other_reagents
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
| ProductDetails | |
|---|---|
| Synonyms | (+)-Incensolacetate;(+)-Incensoleacetate;(1R,2S,5E,9E,12S)-(9Cl)-1,5,9-Trimethyl-12-(1-methylethyl)-15-oxABIcyclo[10.2.1]pentadeca-5,9-dien-2-olacetate |
| ProductType | Chemical |
| Properties | |
| Formula | C22H36O3 |
| MW | 348.5 |
| CAS | 34701-53-6 |
| Source/HostChemicals | Semisyntheticfromincensol(isolatedfromBoswelliapapyrifera). |
| PurityChemicals | ≥95%(HPLC) |
| Appearance | Oil. |
| Solubility | SolubleinDMSO,dichloromethaneorethylether.Insolubleinwater.Almostinsolubleinethanolormethanol. |
| InChiKey | HVBACKJYWZTKCA-XSLBTUIJSA-N |
| ShippingandHandling | |
| Shipping | AMBIENT |
| ShortTermStorage | +4°C |
| LongTermStorage | -20°C |
| HandlingAdvice | Keepcoolanddry. |
| Use/Stability | Stableforatleast2yearsafterreceiptwhenstoredat-20°C. |
| Documents | |
| MSDS |  DownloadPDF |
| ProductSpecificationSheet | |
| Datasheet | DownloadPDF |
- Componentofthefrankincenseessentialoil.
- Activatoroftransientreceptorpotentialvanilloid3(TRPV3),aheat-sensitiveionchannelinvolvedinskinheatsensitivity,Thermoregulationandneurologicalactivities.LesspowerfulTRPV3agoNISTthanincensol(Prod.No.AG-CN2-0482).
- Showsinvivoneuroprotectiveproperties.Causesanxiolytic-likeandantidepressive-likebehavioraleffectsinwild-type(WT)mice.
- Anti-inflammatoryagent.
- ShowntohaveCOX-1andCOX-2inhibitoryactivityandcytotoxicactivityagainstselectedcancercelllines.
ProductReferences
- CancerchemopreventiveeffectsandcytotoxicactivitiesofthetriterpeneacidsfromtheresinofBoswelliacarteri:T.Akihisa,etal.;Biol.Pharm.Bull.29,1976(2006)
- Incensoleacetate,anovelanti-inflammatorycompoundisolatedfromBoswelliaresin,inhibitsnuclearfactor-kappaBactivation:A.Moussaieff,etal.;Mol.Pharmacol.72,1657(2007)
- Incensoleacetate:anovelneuroprotectiveagentisolatedfromBoswelliacarterii:A.Moussaieff,etal.;J.Cereb.BloodFlowMetab.28,1341(2008)
- Incensoleacetate,anincensecomponent,elicitspsychoactivitybyactivatingTRPV3channelsinthebrain:A.Moussaieff,etal.;FASEBJ.22,3024(2008)
- Protectiveeffectsofincensoleacetateoncerebralischemicinjury:A.Moussaieff,etal.;BrainRes.1443,89(2012)
- Incensoleacetatereducesdepressive-likebehaviorandmodulateshippocampalBDNFandCRFexpressionofsubmissiveanimals:A.Moussaieff,etal.;J.Psychopharmacol.26,1584(2012)
- MajorconstituentsofBoswelliacarteriresinexhibitcyclooxygenaseenzymeinhibitionandantiproliferativeactivity:S.I.Ali,etal.;Nat.Prod.Commun.8,1365(2013)
- Neuroactiveandanti-inflammatoryfrankincensecembranes:Astructure-activitystudy:F.Pollastro,etal.;J.Nat.Prod.79,1762(2016)
品牌介绍
Adipogen公司由三个子公司组成，分别是Adipogen,Inc.(韩国),AdipogenSA(瑞士)和 AdipogenCorporation(美国圣地亚哥)。总部设在美国，运营总部在瑞士利斯塔尔。Adipogen公司专门从事生命科学研究试剂的开发，如癌症、免疫、炎症、代谢疾病（糖尿病、肥胖）、干细胞和神经退行性疾病等领域。其重点关注开发创新优质的ELISA试剂盒。另外，也可提供抗体和蛋白产品，Adipogen拥有自己的化学实验室，致力于开发创新型小分子化合物。
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