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商品详细Adipogen/Incensol/AG-CN2-0482-M001/1 mg
Adipogen/Incensol/AG-CN2-0482-M001/1 mg
Adipogen/Incensol/AG-CN2-0482-M001/1 mg
商品编号: AG-CN2-0482-M001
品牌: Adipogen Inc
市场价: ¥2400.00
美元价: 1440.00
产地: 美国(厂家直采)
公司:
产品分类: 其他试剂
公司分类: Other_reagents
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍
More Information
Product Details
Synonyms (-)-Incensol; (-)-Incensole; (1R,2S,5E,9E,12S)-1,5,9-Trimethyl-12-propan-2-yl-15-oxabicyclo[10.2.1]pentadeca-5,9-dien-2-ol
Product Type Chemical
Properties
Formula C20H34O2
MW 306.5
CAS 22419-74-5
Source/Host Chemicals Isolated from Boswellia papyrifera.
Purity Chemicals ≥92% (HPLC)
Appearance Oil.
Solubility Soluble in DMSO, dichloromethane or ethyl ether. Insoluble in water. Almost insoluble in ethanol or methanol.
InChi Key SSBZLMMXFQMHDP-REDNKFHQSA-N
Shipping and Handling
Shipping AMBIENT
Short Term Storage +4°C
Long Term Storage -20°C
Handling Advice Keep cool and dry.
Use/Stability Stable for at least 2 years after receipt when stored at -20°C.
Documents
MSDS Download PDF
Product Specification Sheet
Datasheet Download PDF
  • Component of the frankincense essential oil.
  • Activator of transient receptor potential vanilloid 3 (TRPV3), a heat-sensitive ion channel involved in skin heat sensitivity, thermoregulation and neurological activities. More powerful TRPV3 agonist than incensol acetate (Prod. No. AG-CN2-0484).
  • Potent inhibitor of STAT3. Showed inhibitory activity on IL-6-induced STAT3 activation.
  • Shown to have COX-1 and COX-2 inhibitory activity and cytotoxic activity against selected cancer cell lines.
Product References
  1. Anti-inflammatory activities of the triterpene acids from the resin of Boswellia carteri: N. Banno, et al.; J. Ethnopharmacol. 107, 249 (2006)
  2. Cancer chemopreventive effects and cytotoxic activities of the triterpene acids from the resin of Boswellia carteri: T. Akihisa, et al.; Biol. Pharm. Bull. 29, 1976 (2006)
  3. Major constituents of Boswellia carteri resin exhibit cyclooxygenase enzyme inhibition and antiproliferative activity: S.I. Ali, et al.; Nat. Prod. Commun. 8, 1365 (2013)
  4. Neuroactive and anti-inflammatory frankincense cembranes: A structure-activity study: F. Pollastro, et al.; J. Nat. Prod. 79, 1762 (2016)
品牌介绍
Adipogen公司由三个子公司组成,分别是Adipogen,Inc.(韩国),AdipogenSA(瑞士)和 AdipogenCorporation(美国圣地亚哥)。总部设在美国,运营总部在瑞士利斯塔尔。Adipogen公司专门从事生命科学研究试剂的开发,如癌症、免疫、炎症、代谢疾病(糖尿病、肥胖)、干细胞和神经退行性疾病等领域。其重点关注开发创新优质的ELISA试剂盒。另外,也可提供抗体和蛋白产品,Adipogen拥有自己的化学实验室,致力于开发创新型小分子化合物。