Adipogen/Imperatorin/AG-CN2-0084-M001/1 mg
商品编号：
AG-CN2-0084-M001
品牌：
Adipogen Inc
市场价：
¥700.00
美元价：
420.00
产品分类：
其他试剂
公司分类：
Other_reagents
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
| ProductDetails | |
|---|---|
| Synonyms | Pentosalen;Marmelosin;Ammidin;NSC402949;BAN |
| ProductType | Chemical |
| Properties | |
| Formula | C16H14O4 |
| MW | 270.3 |
| MerckIndex | 14:4925 |
| CAS | 482-44-0 |
| RTECS | LV1575000 |
| Source/HostChemicals | IsolatedfromOpopanaxchironiumL. |
| PurityChemicals | ≥98%(HPLC) |
| Appearance | Whitetooff-whitesolid. |
| Solubility | SolubleinDMSOordimethylformamide.Slightlysolubleinmethanolorwater.Insolubleinethanol. |
| InChiKey | OLOOJGVNMBJLLR-UHFFFAOYSA-N |
| ShippingandHandling | |
| Shipping | AMBIENT |
| ShortTermStorage | +4°C |
| LongTermStorage | -20°C |
| HandlingAdvice | Keepcoolanddry. |
| Use/StABIlity | Stableforatleast2yearsafterreceiptwhenstoredat-20°C. |
| Documents | |
| MSDS |  DownloadPDF |
| ProductSpecificationSheet | |
| Datasheet | DownloadPDF |
- Anticancercompound[1,2,10,14].
- Apoptosisinducer.InducesDNAfragmentationattheG1/Sphaseofthecellcycle[1,2,14].
- HIV-1replicationinhibitor[3].
- Anti-inflammatory[4,9,11].
- Vasodilatationinducer[5].
- IncreasesBMP-2expression(mRNA)andenhanceboneformation[6].
- ModulatorofSMAD1/5/8,p38,ERKpathways[6].
- Exertsanti-hypertrophiceffects[7].
- Caspase-1activityinhibitorinvivoandinvitro[8].
- Antibacterialandantilisteriacompound[12].
- L-Typecalciumchannelblocker[13].
ProductReferences
- Imperatorin,afuranocoumarinfromAngelicadahurica(Umbelliferae),inducescytochromec-dependentapoptosisinhumanpromyelocyticleukaemia,HL-60Cells:H.O.Pae,etal.;Pharmacol.Toxicol.91,40(2002)
- CoumarinsfromOpopanaxchironium.Newdihydrofuranocoumarinsanddifferentialinductionofapoptosisbyimperatorinandheraclenin:G.Appendino,etal.;J.Nat.Prod.67,532(2004)
- ImperatorininhibitsHIV-1replicationthroughanSp1-dependentpathway:R.Sancho,etal.;J.Biol.Chem.279,37349(2004)
- ImperatorininhibitsT-cellproliferationbytargetingthetranscriptionfactorNFAT:N.Marquez,etal.;PlantaMed.70,1016(2004)
- ImperatorininducesvasodilatationpossIBLyviainhibitingvoltagedependentcalciumchannelandreceptor-mediatedCa2+influxandrelease:J.Y.He,etal.;Eur.J.Pharmacol.573,170(2007)
- Enhancementofbonemorphogeneticprotein-2expressionandboneformationbycoumarinderivativesviap38andERK-dependentpathwayinosteoblasts:C.H.Tang,etal.;Eur.J.Pharmacol.579,40(2008)
- Furanocoumarins-imperatorininhibitsmyocardialhypertrophybothinvitroandinvivo:Y.Zhang,etal.;Fitoterapia81,1188(2010)
- Distincteffectsofimperatorinonallergicrhinitis:imperatorininhibitscaspase-1activityinvivoandinvitro:H.A.Oh,etal.;J.Pharmacol.Exp.Ther.339,72(2011)
- Induciblenitricoxidesynthaseandcyclooxygenase-2participateinanti-inflammatoryactivityofimperatorinfromGlehnialittoralis:G.J.Huang,etal.;J.Agric.FoodChem.60,1673(2012)
- AnticancereffectsofimperatorinisolatedfromAngelicadahurica:inductionofapoptosisinHepG2cellsthroughbothdeath-receptor-andmitochondria-mediatedpathways:K.W.Luo,etal.;Chemotherapy57,449(2011)
- ImperatorinAttenuatesLPS-InducedInflammationbySuppressingNF-κBandMAPKsActivationinRAW264.7Macrophages:W.Guo,etal.;Inflammation35,1764(2012)
- Antilisterialpotentialofimperatorinandlimoninfromponcirustrifoliatarafin:A.Rahman,etal.;J.FoodBiochem.36,217(2012)
- StructuralModelingandIdentificationofImperatorinasNovelL-TypeCalciumChannelBlocker:W.Lu,etal.;Med.Chem.9,993(2013)
- Imperatorinsensitizesanoikisandinhibitsanchorage-independentgrowthoflungcancercells:K.Choochuay,etal.;J.Nat.Med.67,599(2013)
品牌介绍
Adipogen公司由三个子公司组成，分别是Adipogen,Inc.(韩国),AdipogenSA(瑞士)和 AdipogenCorporation(美国圣地亚哥)。总部设在美国，运营总部在瑞士利斯塔尔。Adipogen公司专门从事生命科学研究试剂的开发，如癌症、免疫、炎症、代谢疾病（糖尿病、肥胖）、干细胞和神经退行性疾病等领域。其重点关注开发创新优质的ELISA试剂盒。另外，也可提供抗体和蛋白产品，Adipogen拥有自己的化学实验室，致力于开发创新型小分子化合物。
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