Adipogen/Ilimaquinone/AG-CN2-0038-C100/100 µg
商品编号：
AG-CN2-0038-C100
品牌：
Adipogen Inc
市场价：
¥2400.00
美元价：
1440.00
产品分类：
其他试剂
公司分类：
Other_reagents
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
| ProductDetails | |
|---|---|
| Synonyms | 3-[(Decahydro-1α,2β,4aβ-trimethyl-5-methylene-1-naphthyl)methyl]-2-hydroxy-5-methoxybenzoquinone;IQ |
| ProductType | Chemical |
| Properties | |
| Formula | C22H30O4 |
| MW | 358.5 |
| CAS | 71678-03-0 |
| Source/HostChemicals | IsolatedfromAntheliasp. |
| PurityChemicals | ≥98%(HPLC) |
| Appearance | Yellowsolid. |
| Solubility | Solubleinmethanol,ethanol,DMSOorhexane. |
| Identity | Determinedby1H-NMRandMS. |
| InChiKey | JJWITJNSXCXULM-ZKZNVZPYSA-N |
| ShippingandHandling | |
| Shipping | AMBIENT |
| ShortTermStorage | +4°C |
| LongTermStorage | -20°C |
| Use/StABIlity | Stableforatleast2yearsafterreceiptwhenstoredat-20°C. |
| Documents | |
| MSDS |  DownloadPDF |
| ProductSpecificationSheet | |
| Datasheet | DownloadPDF |
- Cytoplasmicmicrotubuleinhibitor[2,6].
- Cellpermeable,antimicrobial,anti-inflammatory,antimitoticandcytotoxiccompound[1,11].
- InducesacompleteandreversIBLebreakdown/disruptionofGolgimembranesintosmallervesicularstructures[2,6].
- BlockstheassociationoftheADP-ribosylationfactorandβ-COPtotheGolgimembrane[3,6].
- Blocksproteintransporttotheplasmamembraneandinhibitsgapjunctionalcommunication[2,3,9].
- HIV-1inhibitor[4].
- Blocksthecytotoxicityofricinanddiphtheriatoxin[5].
- S-Adenosylhomocysteinasehydrolaseinhibitorandcellularmethylationsinhibitor[7,12].
- DNApolymeraseβlyaseactivityinhibitor[8].
- Anti-cancercompound.[10].
ProductReferences
- Ilimaquinone,asesquiterpenoidquinonefromamarinesponge:R.T.Luibrand,etal.;Tetrahedron35,609(1979)
- MicrotubuleindependentvesiculationofGolgimembranesandthereassemblyofvesiclesintoGolgistacks:B.Veit,etal.;J.Cell.Biol.122,1197(1993)
- CompletevesiculationofGolgimembranesandinhibitionofproteintransportbyanovelseaspongemetabolite,ilimaquinone:P.A.Takizawa,etal.;Cell73,1079(1993)
- Theinteractionofillimaquinone,aselectiveinhibitoroftheRNaseHactivity,withthereversetranscriptasesofhumanimmunodeficiencyandmurineleukemiaretroviruses:S.Loya&A.Hizi;J.Biol.Chem.268,9323(1993)
- Ilimaquinoneinhibitsthecytotoxicitiesofricin,diphtheriatoxin,andotherproteintoxinsinVerocells:M.P.Nambiar&H.C.Wu;Exp.CellRes.219,671(1995)
- Golgi-disturbingagents:A.Dinter&E.G.Berger;Histochem.CellBiol.109,571(1998)
- Interactionsof(-)-ilimaquinonewithmethylationenzymes:implicationsforvesicular-mediatedsecretion:H.S.Radeke,etal.;Chem.Biol.6,639(1999)
- MarinesesquiterpenoidsthatinhibitthelyaseactivityofDNApolymerasebeta:S.Cao,etal.;J.Nat.Prod.67,1716(2004)
- Ilimaquinoneinhibitsgapjunctionalcommunicationinaconnexinisotype-specificmanner:V.Cruciani&S.O.Mikalsen;Exp.CellRes.304,136(2005)
- Ilimaquinone,amarinespongemetabolite,displaysanticanceractivityviaGADD153-mediatedpathway:P.H.Lu,etal.;Eur.J.Pharmacol.556,45(2007)
- ComparisonoftheBIOLOGicalpropertiesofseveralmarinesponge-derivedsesquiterpenoidquinones:C.A.Motti,etal.;Molecules12,1376(2007)
- AnewstructuralclassofS-adenosylhomocysteinehydrolaseinhibitors:B.G.Kim,etal.;Bioorg.Med.Chem.17,6707(2009)
品牌介绍
Adipogen公司由三个子公司组成，分别是Adipogen,Inc.(韩国),AdipogenSA(瑞士)和 AdipogenCorporation(美国圣地亚哥)。总部设在美国，运营总部在瑞士利斯塔尔。Adipogen公司专门从事生命科学研究试剂的开发，如癌症、免疫、炎症、代谢疾病（糖尿病、肥胖）、干细胞和神经退行性疾病等领域。其重点关注开发创新优质的ELISA试剂盒。另外，也可提供抗体和蛋白产品，Adipogen拥有自己的化学实验室，致力于开发创新型小分子化合物。
联络我们
