Adipogen/Heliquinomycin/AG-CN2-0091-C250/250 µg
商品编号：
AG-CN2-0091-C250
品牌：
Adipogen Inc
市场价：
¥5000.00
美元价：
3000.00
产品分类：
其他试剂
公司分类：
Other_reagents
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
| Product Details | |
|---|---|
| Synonyms | Rubymycin; NSC 702208 |
| Product Type | Chemical |
| Properties | |
| Formula | C33H30O17 |
| MW | 698.6 |
| CAS | 178182-49-5 |
| RTECS | WG9689000 |
| Source/Host Chemicals | Isolated from Streptomyces sp. MJ929-SF2. |
| Purity Chemicals | ≥80% (HPLC) |
| Appearance | Red powder. |
| Solubility | Soluble in DMSO, ethanol, chloroform or ethyl acetate. Insoluble in water or n-hexane. |
| Declaration | Manufactured by the Institute of Microbial Chemistry (BIKAKEN). |
| InChi Key | MLFZQFHGXSVTGX-VJANPNJTSA-N |
| Shipping and Handling | |
| Shipping | BLUE ICE |
| Short Term Storage | +4°C |
| Long Term Storage | -20°C |
| Handling Advice | Keep cool and dry. |
| Use/Stability | Stable for at least 3 years after receipt when stored at -20°C. |
| Documents | |
| MSDS |
 Download PDF |
| Product Specification Sheet | |
| Datasheet |
Download PDF |
- Antibiotic [1].
- DNA helicase inhibitor [1]. Inhibits the DNA helicase activity of the human minichromosome maintenance (MCM) 4/6/7 complex [3, 4].
- Topoisomerase I and II inhibitor (weaker than DNA helicase) [2].
- DNA and RNA synthesis inhibitor in cell culture. Does not inhibit protein synthesis [2].
- Induces cell cycle arrest [2].
- Anticancer compound [1, 2].
- Antibacterial against Gram-positive bacteria [1].
Product References
- Heliquinomycin, a new inhibitor of DNA helicase, produced by Streptomyces sp. MJ929-SF2 I. Taxonomy, production, isolation, physico-chemical properties and biological activities: M. Chino, et al.; J. Antibiot. 49, 752 (1996)
- Effect of a novel antibiotic, heliquinomycin, on DNA helicase and cell growth: M. Chino, et al.; J. Antibiot. 51, 480 (1998)
- Effect of heliquinomycin on the activity of human minichromosome maintenance 4/6/7 helicase: Y. Ishimi, et al.; FEBS J. 276, 3382 (2009)
- Interaction of heliquinomycin with single-stranded DNA inhibits MCM4/6/7 helicase: T. Sugiyama, et al.; J. Biochem. 151, 129 (2012)
品牌介绍
Adipogen公司由三个子公司组成，分别是Adipogen,Inc.(韩国),AdipogenSA(瑞士)和 AdipogenCorporation(美国圣地亚哥)。总部设在美国，运营总部在瑞士利斯塔尔。Adipogen公司专门从事生命科学研究试剂的开发，如癌症、免疫、炎症、代谢疾病（糖尿病、肥胖）、干细胞和神经退行性疾病等领域。其重点关注开发创新优质的ELISA试剂盒。另外，也可提供抗体和蛋白产品，Adipogen拥有自己的化学实验室，致力于开发创新型小分子化合物。
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