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Adipogen/Glycochenodeoxycholic acid sodium salt/CDX-G0033-M500/500 mg
| ProductDetails | |
|---|---|
| Synonyms | Sodiumglycochenodeoxycholate;GCDCA;NSC681056;Chenylglycinesodium;N-(3α,7α-Dihydroxy-24-oxocholan-24-yl)glycinesodiumsalt |
| ProductType | Chemical |
| Properties | |
| Formula | C26H42NNaO5 |
| MW | 471.61 |
| CAS | 16564-43-5 |
| Source/HostChemicals | Synthetic. |
| PurityChemicals | ≥97%(HPLC) |
| Appearance | Whitetooff-whitepowder. |
| Solubility | SlightlysolubleinDMSO,ethanolormethanol(10mg/ml)andinwater. |
| Identity | Determinedby1H-NMR. |
| Declaration | ManufacturedbyChemodex. |
| OtherProductData | ClickhereforOriginalManufacturerProductDatasheet Ourproductdescriptionmaydifferslightlyfromtheoriginalmanufacturersproductdatasheet. |
| InChiKey | AAYACJGHNRIFCT-YRJJIGPTSA-M |
| ShippingandHandling | |
| Shipping | AMBIENT |
| ShortTermStorage | +4°C |
| LongTermStorage | +20°C |
| HandlingAdvice | Keepcoolanddry. Protectfromlightandmoisture. |
| Use/StABIlity | Stableforatleast2yearsafterreceiptwhenstoredat-20°C. |
| Documents | |
| MSDS | No |
| ProductSpecificationSheet | |
| Datasheet |  DownloadPDF |
Glycochenodeoxycholicacid(GCDCA)isabilesaltformedintheliverthatactsasabiosurfactanttosolubilizelipidsforabsorptionandisitselfabsorbed.GCDCAfunctionsasacholeretic,increasingthevolumeofbilesecretedfromtheliver,andacholagogue,promotingthedischargeofbilefromthedigestivesystem.GCDCAhasbeenusedtodemonstratearoleforbileacidsinpromotingcolorectalcarcinogenesisandtoinhibitcalciumhydroxyapatiteprecipitationtostudythepathogenesisofblackpigmentgallstones.ThisproducthasalsobeenshowntoinduceapoptosisinisolatedhepatocytesviamodulationofPKCactivity.Thiscompoundisusedasananionicdetergenttosolubilizelipidsandasachiralreagent.
(1)S.Barnes,etal.;J.LipidRes.20,952(1979)|(2)S.M.Qiu,etal.;J.Clin.Invest.88,1265(1991)|(3)B.Gonzalez,etal.;Mol.Cell.Biochem.207,19(2000)|(4)M.Iwata,etal.;Hepatol.Res.25,329(2003)|(5)S.Ishizuka,etal.;Biomed.Res.33,159(2012)
