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当前位置: 首页 > 产品中心 > Other_reagents > Adipogen/Gilnocarcin V/BVT-0256-C250/250µg
商品详细Adipogen/Gilnocarcin V/BVT-0256-C250/250µg
Adipogen/Gilnocarcin V/BVT-0256-C250/250µg
Adipogen/Gilnocarcin V/BVT-0256-C250/250µg
商品编号: BVT-0256-C250
品牌: Adipogen Inc
市场价: ¥2400.00
美元价: 1440.00
产地: 美国(厂家直采)
公司:
产品分类: 其他试剂
公司分类: Other_reagents
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍
MoreInformation
ProductDetails
SynonymsAnandimycinA;ToromycinA;NSC338943;DC-38-V;Antibiotic1072B
ProductTypeChemical
Properties
FormulaC27H26O9
MW494.5
CAS77879-90-4
RTECSDI2240000
Source/HostChemicalsIsolatedfromStreptomycessp.Gö3592.
PurityChemicals≥98%(HPLC)
AppearanceYellowsolid.
SolubilitySolubleinDMSO.
IdentityDeterminedby1H-NMR.
DeclarationManufacturedbyBioViotica.
InChiKeyXCWHINLKQMCRON-UCDARZNSSA-N
ShippingandHandling
ShippingBLUEICE
ShortTermStorage+4°C
LongTermStorage-20°C
HandlingAdviceProtectfromlightwheninsolution.
Use/StABIlityStableforatleast1yearafterreceiptwhenstoredat-20°C.
Stocksolutionsarestableforatleast3monthswhenstoredat-20°C.
Documents
MSDSDownloadPDF
ProductSpecificationSheet
DatasheetDownloadPDF
  • Antibiotic.
  • Antitumorcompound.
  • WeaklyactiveagainstGram-positivebacteriaandfungi.
  • Mediatesauniquecross-linkingreactionbetweenDNAandhistoneH3bylight.
  • SinglestrandscissionandcovalentbindingtoDNAafterphotoactivation.
ProductReferences
  1. Gilvocarcins,newantitumorantibiotics.1.Taxonomy,fermentation,isolationandBIOLOGicalactivities:H.Nakano,etal.;J.Antibiot.(Tokyo)34,266(1981)
  2. ActivationofantitumoragentgilvocarcinsbyvisIBLelight:R.K.ElespuruandS.K.Gonda;Science223,69(1984)
  3. PhotosensitizedDNAbreaksandDNA-to-proteincrosslinksinducedinhumancellsbyantitumoragentgilvocarcinV:M.J.Peak,etal.;Chem.Biol.Interact.67,267(1988)
  4. Biochemicalcharacterisationofelsamicinandothercoumarin-relatedantitumouragentsaspotentinhibitorsofhumantopoisomeraseII:A.Lorico&B.H.Long;Eur.J.Cancer29A,1985(1993)
  5. PhotophysicalpropertiesofgilvocarcinsVandMandtheirbindingconstanttocalfthymusDNA:R.Oyola,etal.;Photochem.Photobiol.65,802(1997)
  6. HistoneH3andheatshockproteinGRP78areselectivelycross-linkedtoDNAbyphotoactivatedgilvocarcinVinhumanfibroblasts:A.MatsumotoandP.C.Hanawalt;CancerRes.60,3921(2000)
  7. ThecompletegeneclusteroftheantitumoragentgilvocarcinVanditsimplicationforthebiosynthesisofthegilvocarcins:C.Fischer,etal.;J.Am.Chem.Soc.125,7818-7819(2003)
  8. Multi-oxygenasecomplexesofthegilvocarcinandjadomycinbiosyntheses:M.K.Kharel,etal.;J.Am.Chem.Soc.129,3780-3781(2007)
  9. InactivationoftheketoreductasegilUgeneofthegilvocarcinbiosyntheticgeneclusteryieldsnewanalogueswithpartlyimprovedbiologicalactivity:T.Liu,etal.;ChemBioChem10,278-286(2009)
  10. TotalsynthesisoftheantitumornaturalproductpolycarcinVandevaluationofitsDNAbindingprofile:X.Cai,etal.;Org.Lett.16,2962(2014) 
品牌介绍
Adipogen公司由三个子公司组成,分别是Adipogen,Inc.(韩国),AdipogenSA(瑞士)和 AdipogenCorporation(美国圣地亚哥)。总部设在美国,运营总部在瑞士利斯塔尔。Adipogen公司专门从事生命科学研究试剂的开发,如癌症、免疫、炎症、代谢疾病(糖尿病、肥胖)、干细胞和神经退行性疾病等领域。其重点关注开发创新优质的ELISA试剂盒。另外,也可提供抗体和蛋白产品,Adipogen拥有自己的化学实验室,致力于开发创新型小分子化合物。