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当前位置: 首页 > 产品中心 > Other_reagents > Adipogen/G418 . sulfate/AG-CN2-0030-G001/1 g
商品详细Adipogen/G418 . sulfate/AG-CN2-0030-G001/1 g
Adipogen/G418 . sulfate/AG-CN2-0030-G001/1 g
Adipogen/G418 . sulfate/AG-CN2-0030-G001/1 g
商品编号: AG-CN2-0030-G001
品牌: Adipogen Inc
市场价: ¥940.00
美元价: 564.00
产地: 美国(厂家直采)
公司:
产品分类: 其他试剂
公司分类: Other_reagents
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍
MoreInformation
ProductDetails
SynonymsGeneticin;AntibioticG418;BRN1669188
ProductTypeChemical
Properties
FormulaC20H40N4O10.2H2SO4
MW496.6.196.1
CAS108321-42-2
RTECSCB9378500
Source/HostChemicalsIsolatedfromMicromonosporarhodorangea.
PurityChemicals≥98%(TLC)
AppearanceWhitetooff-whitesolid.
SolubilitySolubleinwater(upto50mg/ml).
BIOLOGicalActivityAssay:≥700μg/mg
BiologicalAssay:ED50Resistant:≥2500μg/ml
BiologicalAssay:ED50Sensitivity:≤400μg/ml
InChiKeyBRZYSWJRSDMWLG-UHFFFAOYSA-N
ShippingandHandling
ShippingAMBIENT
ShortTermStorage+4°C
LongTermStorage-20°C
HandlingAdviceAvoidfreeze/thawcycles.
Use/StABIlityStableforatleast2yearsafterreceiptwhenstoredat-20°C.
Documents
MSDSDownloadPDF
ProductSpecificationSheet
DatasheetDownloadPDF
  • Antibiotic[1].
  • Cytotoxictoprokaryoticandeukaryoticcellsbyinhibitingtheproteinsynthesis[1,3,4,6].
  • Apoptosisinducer[5].
  • Widelyemployedintheselectionofeukaryoticexpressionvectors,incombinationwitheitheraminoglycosidephosphotransferase3"orAPHII[2].
  • Antiviral[7,8].
ProductReferences
  1. AntibioticG-418,anewMicromonospora-producedaminoglycosidewithactivityagainstprotozoaandhelminths:fermentation,isolation,andpreliminarycharacterization:G.H.Wagman,etal.;Antimicrob.AgentsChemother.6,144(1974)
  2. PhosphatidylinositolphospholipaseCisactivatedallostericallybytheaminoglycosideG418.2-deoxy-2-fluoro-scyllo-inositol-1-O-dodecylphosphonateanditsanalogsinhibitglycosylphosphatidylinositolphospholipaseC:J.C.Morris,etal.;J.Biol.Chem.271,15468(1996)
  3. AdditionofG418andotheraminoglycosideantibioticstomammaliancellsresultsinthereleaseofGPI-anchoredproteins:M.Kung,etal.;FEBSLett.409,333(1997)
  4. TheeffectsofG418onthegrowthandmetabolismofrecombinantmammaliancelllines:C.A.Yallop&I.Svendsen;Cytotechnology35,101(2001)
  5. Cytochromecreleaseandendoplasmicreticulumstressareinvolvedincaspase-dependentapoptosisinducedbyG418:Q.H.Jin,etal.;Cell.Mol.LifeSci.61,1816(2004)
  6. ExpressionanddistributionofHSP27inresponsetoG418indifferenthumanbreastcancercelllines:L.Qian,etal.;Histochem.CellBiol.126,593(2006)
  7. Antiviralactivityofgeneticinagainstbovineviraldiarrhoeavirus:A.V.Birk,etal.;Antivir.Chem.Chemother.19,33(2008)
  8. Antiviralactivityofgeneticinagainstdenguevirus:X.G.Zhang,etal.;AntiviralRes.83,21(2009)
品牌介绍
Adipogen公司由三个子公司组成,分别是Adipogen,Inc.(韩国),AdipogenSA(瑞士)和 AdipogenCorporation(美国圣地亚哥)。总部设在美国,运营总部在瑞士利斯塔尔。Adipogen公司专门从事生命科学研究试剂的开发,如癌症、免疫、炎症、代谢疾病(糖尿病、肥胖)、干细胞和神经退行性疾病等领域。其重点关注开发创新优质的ELISA试剂盒。另外,也可提供抗体和蛋白产品,Adipogen拥有自己的化学实验室,致力于开发创新型小分子化合物。