Adipogen/FTY720 . hydrochloride/AG-CR1-3587-M005/5 mg
商品编号：
AG-CR1-3587-M005
品牌：
Adipogen Inc
市场价：
¥400.00
美元价：
240.00
产品分类：
其他试剂
公司分类：
Other_reagents
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
| ProductDetails | |
|---|---|
| Synonyms | 2-Amino-2-[2-(4-octylphenyl)ethyl]-1,3-propanediol.HCl; Fingolimod;Gilenya |
| ProductType | Chemical |
| Properties | |
| Formula | C19H33NO2.HCl |
| MW | 307.4.36.5 |
| CAS | 162359-56-0 |
| RTECS | TY3130000 |
| Source/HostChemicals | SyntheticanalogofISP-1,isolatedfromIsariasinclairii. |
| PurityChemicals | ≥98% |
| Appearance | Whitesolid. |
| Solubility | SolubleinDMSO,ethanolorDMF. |
| InChiKey | SWZTYAVBMYWFGS-UHFFFAOYSA-N |
| ShippingandHandling | |
| Shipping | AMBIENT |
| ShortTermStorage | +4°C |
| LongTermStorage | -20°C |
| HandlingAdvice | Keepcoolanddry. |
| Use/StABIlity | Stableforatleast2yearsafterreceiptwhenstoredat-20°C. |
| Documents | |
| MSDS |  DownloadPDF |
| ProductSpecificationSheet | |
| Datasheet | DownloadPDF |
- Cellpermeableimmunosuppressordisplayinglymphocytesequestrationpropertiesandusedfortreatmentinmultiplesclerosis[1,6].
- Potentsphingosine1-phosphate(S1P)receptor(S1P1,S1P3,S1P4,andS1P5)agoNISTwhenphosphorylatedbysphingosinekinase[2,4].
- SphingosinetransporterAbcb1andleukotrieneC4transporterAbcc1activityenhancer[3].
- CytosolicphospholipaseA2inhibitor,independentofsphingosine1-phosphatereceptors[5].
- Autophagyinducer[7].
- Apoptosisinducer[8].
ProductReferences
- FTY720:Alteredlymphocytetrafficresultsinallograftprotection:V.Brinkmann,etal.;Transplantation72,764(2001)
- TheimmunemodulatorFTY720targetssphingosine1-phosphatereceptors:V.Brinkmann,etal.;J.Biol.Chem.277,21453(2002)
- FTY720stimulatesmultidrugtransporter-andcysteinylleukotriene-dependentTcellchemotaxistolymphnodes:S.M.Honig,etal.;J.Clin.Invest.111,627(2003)
- LymphocyteegressfromthymusandperipherallymphoidorgansisdependentonS1Preceptor1:M.Matloubian,etal.;Nature427,355(2004)
- TheimmunosuppressantdrugFTY720inhibitscytosolicphospholipaseA2independentlyofsphingosine-1-phosphatereceptors:S.G.Payne,etal.;Blood109,1077(2007)
- Fingolimod(FTY720):arecentlyapprovedmultiplesclerosisdrugbasedonafungalsecondarymetabolite:C.R.Strader,etal.;J.Nat.Prod.74,900(2011)
- AutophagyinducedbyFTY720promotesapoptosisinU266cells:A.Liao,etal.;Eur.J.Pharm.Sci.45,600(2012)
- InductionofbraintumorstemcellapoptosisbyFTY720:apotentialtherapeuticagentforglioblastoma:A.Estrada-Bernal,etal.;NeuroOncol.14,405(2012)
品牌介绍
Adipogen公司由三个子公司组成，分别是Adipogen,Inc.(韩国),AdipogenSA(瑞士)和 AdipogenCorporation(美国圣地亚哥)。总部设在美国，运营总部在瑞士利斯塔尔。Adipogen公司专门从事生命科学研究试剂的开发，如癌症、免疫、炎症、代谢疾病（糖尿病、肥胖）、干细胞和神经退行性疾病等领域。其重点关注开发创新优质的ELISA试剂盒。另外，也可提供抗体和蛋白产品，Adipogen拥有自己的化学实验室，致力于开发创新型小分子化合物。
联络我们
