Adipogen/Fipronil/AG-CR1-3648-M100/100 mg
商品编号：
AG-CR1-3648-M100
品牌：
Adipogen Inc
市场价：
¥1000.00
美元价：
600.00
产品分类：
其他试剂
公司分类：
Other_reagents
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
| ProductDetails | |
|---|---|
| Synonyms | Fluocyanobenpyrazole;Termidor;5-Amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-(trifluoromethanesulfinyl)-1H-pyrazole-3-carbonitrile |
| ProductType | Chemical |
| Properties | |
| Formula | C12H4Cl2F6N4OS |
| MW | 437.2 |
| CAS | 120068-37-3 |
| PurityChemicals | ≥98%(NMR) |
| Appearance | Whitetoyellowsolid. |
| Solubility | SolubleinDMSO,methanol,ethanoloracetone.Insolubleinwater. |
| InChiKey | ZOCSXAVNDGMNBV-UHFFFAOYSA-N |
| ShippingandHandling | |
| Shipping | AMBIENT |
| ShortTermStorage | +20°C |
| LongTermStorage | +4°C |
| Use/StABIlity | Stableforatleast2yearsafterreceiptwhenstoredat+4°C. |
| Documents | |
| MSDS |  DownloadPDF |
| ProductSpecificationSheet | |
| Datasheet | DownloadPDF |
- Alzheimerinducingagent(Alzheimerogen).
- PotentGABAreceptorα-4subunitandβ-3subunitinhibitor.
- Broad-rangeinsecticide.BlocksGABAA-gatedchloridechannelsandglutamate-activatedchloridechannels(GluCls)inthecentralnervoussystem,resultinginoverexcitationoftheinsectsnervoussystemandmuscles.
- Inducesoxidativestressinmousekidneyandbrain.
- IncreasesCYP1A1,CYP2B6,CYP3A4andCYP3A5transcript,proteinandenzymeactivitylevels.
ProductReferences
- ActionofPhenylpyrazoleInsecticidesattheGABA-GatedChlorideChannel:L.M.Cole,etal.;Pestic.Biochem.Physiol.46,47(1993)
- Actionsoftheinsecticidefipronil,ondieldrin-sensitiveand-resistantGABAreceptorsofDrosophilamelanogaster:A.M.Hosie,etal.;Br.J.Pharmacol.115,909(1995)
- Ionchannels:moleculartargetsofneuroactiveinsecticides:V.Raymond-Delpech,etal.;Invert.Neurosci.5,119(2005)
- Glutamate-activatedchloridechannels:Uniquefiproniltargetspresentininsectsbutnotinmammals:T.Narahashi,etal.:Pestic.Biochem.Physiol.97,149(2010)
- Fipronilinducedoxidativestressinkidneyandbrainofmice:protectiveeffectofvitaminEandvitaminC:P.C.Badgujar,etal.;Pestic.Biochem.Physiol.118,10(2015)
- Identificationofchemicalsthatmimictranscriptionalchangesassociatedwithautism,brainagingandneurodegeneration:B.L.Pearson,etal.;Nat.Commun.(2015)
- Specifictriazineherbicidesinduceamyloid-β42production:E.Portelius,etal.;J.AlzheimersDis.54,1593(2016)
- Impactofenvironmentalchemicalsonthetranscriptomeofprimaryhumanhepatocytes:Potentialforhealtheffects:R.D.Mitchell,etal.;J.Biochem.Mol.Toxicol.30,375(2016)
品牌介绍
Adipogen公司由三个子公司组成，分别是Adipogen,Inc.(韩国),AdipogenSA(瑞士)和 AdipogenCorporation(美国圣地亚哥)。总部设在美国，运营总部在瑞士利斯塔尔。Adipogen公司专门从事生命科学研究试剂的开发，如癌症、免疫、炎症、代谢疾病（糖尿病、肥胖）、干细胞和神经退行性疾病等领域。其重点关注开发创新优质的ELISA试剂盒。另外，也可提供抗体和蛋白产品，Adipogen拥有自己的化学实验室，致力于开发创新型小分子化合物。
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