Adipogen/Finasteride/AG-CR1-3589-M025/25 mg
商品编号：
AG-CR1-3589-M025
品牌：
Adipogen Inc
市场价：
¥400.00
美元价：
240.00
产品分类：
其他试剂
公司分类：
Other_reagents
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
| ProductDetails | |
|---|---|
| Synonyms | MK906;L-652,931;BRN4269024 |
| ProductType | Chemical |
| Properties | |
| Formula | C23H36N2O2 |
| MW | 372.5 |
| MerckIndex | 14:4082 |
| CAS | 98319-26-7 |
| RTECS | CL5245000 |
| PurityChemicals | ≥98%(HPLC) |
| Appearance | Whitetooff-whitesolid. |
| Solubility | SolubleinDMSO,DMF,ethanolormethanol.Sparinglysolubleinwater. |
| InChiKey | DBEPLOCGEIEOCV-WSBQPABSSA-N |
| ShippingandHandling | |
| Shipping | AMBIENT |
| ShortTermStorage | +4°C |
| LongTermStorage | +4°C |
| HandlingAdvice | Keepcoolanddry. |
| Use/StABIlity | Stableforatleast2yearsafterreceiptwhenstoredat+4°C. |
| Documents | |
| MSDS |  DownloadPDF |
| ProductSpecificationSheet | |
| Datasheet | DownloadPDF |
- Potent,specificandcompetitiveinhibitoroftypeII5α-reductase(enzymewhichconvertstestosteronetothemorepotent5α-dihydrotestosterone)[1,3].
- Anticancercompound[2,6,7].
- Apoptosismodulator[2,6].
- EnhancestheactionofGABAatGABA(A)receptors,whichleadstoneurologicalimplications[4].
- Inhibittestosterone-inducedtypeIprocollagenandTGF-β1expressioninhumanscalpdermalfibroblastsinamodelofandrogenicalopecia[5].
- Drugforthetreatmentofmaleandrogeneticalopecia[8].
- Potentialroleinneuropsychiatricdisorders[9].
ProductReferences
- Finasteride:thefirst5alpha-reductaseinhibitor:S.L.Sudduth&M.J.Koronkowski;Pharmacotherapy13,309(1993)
- InductionofapoptosisinratventralprostatebyfinasterideisassociatedwithalterationinMAPkinasepathwaysandBcl-2relatedfamilyofproteins:H.Huynh;Int.J.Oncol.20,1297(2002)
- Steroid5α-reductaseinhibitors:R.Flores,etal.;MiniRev.Med.Chem.3,225(2003)
- Anewlookatthe5alpha-reductaseinhibitorfinasteride:D.A.Finn,etal.;CNSDrugRev.12,53(2006)
- Perifollicularfibrosis:Pathogeneticroleinandrogeneticalopecia;H.G.Yoo,etal.;Biol.Pharm.Bull.29,1246(2006)
- FinasterideinducesapoptosisviaBcl-2,Bcl-xL,Baxandcaspase-3proteinsinLNCaPhumanprostatecancercellline:J.M.Golbano,etal.;Int.J.Oncol.32,919(2008)
- Molecularprofilesoffinasterideeffectsonprostatecarcinogenesis:CancerPrev.Res.2,518(2009)
- Maleandrogeneticalopecia:D.Rathnayake&R.Sinclair;ExpertOpin.Pharmacother.11,1295(2010)
- Steroid5α-reductaseasanoveltherapeutictargetforschizophreniaandotherneuropsychiatricdisorders:S.Paba,etal.;Curr.Pharm.Des.17,151(2011)
品牌介绍
Adipogen公司由三个子公司组成，分别是Adipogen,Inc.(韩国),AdipogenSA(瑞士)和 AdipogenCorporation(美国圣地亚哥)。总部设在美国，运营总部在瑞士利斯塔尔。Adipogen公司专门从事生命科学研究试剂的开发，如癌症、免疫、炎症、代谢疾病（糖尿病、肥胖）、干细胞和神经退行性疾病等领域。其重点关注开发创新优质的ELISA试剂盒。另外，也可提供抗体和蛋白产品，Adipogen拥有自己的化学实验室，致力于开发创新型小分子化合物。
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