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当前位置: 首页 > 产品中心 > Other_reagents > Adipogen/Ferutinin (high purity)/AG-CN2-0007-M010/10 mg
商品详细Adipogen/Ferutinin (high purity)/AG-CN2-0007-M010/10 mg
Adipogen/Ferutinin (high purity)/AG-CN2-0007-M010/10 mg
Adipogen/Ferutinin (high purity)/AG-CN2-0007-M010/10 mg
商品编号: AG-CN2-0007-M010
品牌: Adipogen Inc
市场价: ¥3400.00
美元价: 2040.00
产地: 美国(厂家直采)
公司:
产品分类: 其他试剂
公司分类: Other_reagents
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍
MoreInformation
ProductDetails
Synonyms4-Oxy-6-(4-oxybenzoyloxy)dauc-8,9-en;Tefestrol
ProductTypeChemical
Properties
FormulaC22H30O4
MW358.5
CAS41743-44-6
Source/HostChemicalsSemisynthetic.
PurityChemicals≥98%(HPLC)
AppearanceWhitetooff-whitesolid.
SolubilitySolubleinDMSO,acetone,dichloromethaneorethylacetate.
InChiKeyCYSHNJQMYORNJI-YUVXSKOASA-N
ShippingandHandling
ShippingAMBIENT
ShortTermStorage+4°C
LongTermStorage-20°C
HandlingAdviceKeepunderinertgas.
Protectfromlight.
Protectfrommoistureandoxygen.
Use/StABIlityStableforatleast2yearsafterreceiptwhenstoredat+4°C.
Documents
MSDSDownloadPDF
ProductSpecificationSheet
DatasheetDownloadPDF
  • Potent,naturallyoccuringnon-steroidestrogeniccompound.
  • Tooltopromotemitochondrialcalciumoverloadandtopromotecalcium-dependentopeningofthemitochondrialpermeabilitytransitionpore(mPTP)[1,3,4].
  • StrongagoNISTforestrogenreceptor(ER)αandagonist/antagonistforERβ[2,8].
  • Calciumionophoretic[4,11]
  • Apoptosismodulator[4].
  • Antiproliferative[5,7].
  • Increasesnitricoxidesynthaseactivityandphosphoinositidesbreakdowninnervoustissue[6].
  • Showsaphrodisiacandanti-sexualimpotenceactivities[6].
  • Anti-osteoporotic.Preventsosteoporosiscausedbysevereestrogendeficiency[9].
  • ModestAChEinhibitor[10].
ProductReferences
  1. Ionophoreticpropertiesofferutinin:M.V.Zamaraeva,etal.;CellCalcium22,235(1997)
  2. Terpenoidsfoundintheumbelliferaefamilyactasagonists/antagonistsforER(alpha)andERbeta:differentialtranscriptionactivitybetweenferutinine-ligandedER(alpha)andERbeta:K.Ikeda,etal.;BBRC291,354(2002)
  3. Actionsofionomycin,4-BrA23187andanovelelectrogenicCa2+ionophoreonmitochondriainintactcells:A.Y.Abramov&M.R.Duchen;CellCalcium33,101(2003)
  4. CalciumionophoreticandapoptoticeffectsofferutinininthehumanJurkatT-cellline:A.Macho,etal.;Biochem.Pharmacol.68,875(2004) 
  5. AntiproliferativeeffectsofdaucaneestersfromFerulacommunisandF.arrigoniionhumancoloncancercelllines:F.Poli,etal.;Phytother.Res.19,152(2005)
  6. Ferutininstimulatesnitricoxidesynthaseactivityinmedianeminenceoftherat:T.Colman-Saizarbitoria,etal.;J.Ethnopharmacol.106,327(2006)
  7. ActivityofelaeochytrinAfromFerulaelaeochytrisonleukemiacelllines:R.Alkhatib,etal.;Phytochemistry69,2979(2008)
  8. ThephytoestrogenferutininaffectsfemalesexualbehaviormodulatingERalphaexpressioninthehypothalamus:P.Zanoli,etal.;Behav.BrainRes.199,283(2009)
  9. Influenceofferutininonbonemetabolisminovariectomizedrats.II:roleinrecoveringosteoporosis:M.Ferretti,etal.;J.Anat.217,4(2010)
  10. Identificationofnon-alkaloidacetylcholinesteraseinhibitorsfromFerulagocampestris(Besser)Grecescu(Apiaceae):S.Dall"acqua,etal.;Fitoterapia81,1208(2010)
  11. Ferutininestructure:A.I.Saidkhodjaev,etal.;Chem.Nat.Comp.1,28(1973)
品牌介绍
Adipogen公司由三个子公司组成,分别是Adipogen,Inc.(韩国),AdipogenSA(瑞士)和 AdipogenCorporation(美国圣地亚哥)。总部设在美国,运营总部在瑞士利斯塔尔。Adipogen公司专门从事生命科学研究试剂的开发,如癌症、免疫、炎症、代谢疾病(糖尿病、肥胖)、干细胞和神经退行性疾病等领域。其重点关注开发创新优质的ELISA试剂盒。另外,也可提供抗体和蛋白产品,Adipogen拥有自己的化学实验室,致力于开发创新型小分子化合物。