Adipogen/Enniatin A1/AG-CN2-0478-M001/1 mg
商品编号：
AG-CN2-0478-M001
品牌：
Adipogen Inc
市场价：
¥2600.00
美元价：
1560.00
产品分类：
其他试剂
公司分类：
Other_reagents
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
| ProductDetails | |
|---|---|
| Synonyms | 2-(N-Methyl-L-valine)enniatinA |
| ProductType | Chemical |
| Properties | |
| Formula | C35H61N3O9 |
| MW | 667.9 |
| MerckIndex | 14:3585 |
| CAS | 4530-21-6 |
| Source/HostChemicals | IsolatedfromfungusFusariumsp. |
| PurityChemicals | ≥98%(HPLC) |
| Appearance | Whitetooff-whitesolid. |
| Solubility | SolubleinDMSO,ethanol,methanolorDMF.Almostinsolubleinwater. |
| InChiKey | OWUREPXBPJFMOK-CIRFPNLUSA-N |
| ShippingandHandling | |
| Shipping | AMBIENT |
| ShortTermStorage | +4°C |
| LongTermStorage | -20°C |
| HandlingAdvice | Keepcoolanddry. Protectfromlight. |
| Use/StABIlity | Stableforatleast2yearsafterreceiptwhenstoredat-20°C. |
| Documents | |
| MSDS |  DownloadPDF |
| ProductSpecificationSheet | |
| Datasheet | DownloadPDF |
- Cyclohexadepsipeptidemycotoxin.Oneoffourmajoranalogsintheenniatincomplex.Commonlyfoundfoodcontaminantincerealsandtheirproducts.
- Ionophoreantibiotic.Incorporationintothecellmembraneformsdimericstructuresthattransportmonovalentionsacrossthemembrane(especiallythemitochondrialmembranes)affectingoxidativephosphorylationuncoupling.
- Anticancercompound.Triggersapoptosisinseveralcancercelllines.
- Inducedapoptosisincancercells(H4IIErathepatomacells),decreasingtheactivationofthecellproliferationkinase,ERK(p44/p42)andinhibitingTNF-α-inducedNF-κBactivation.
- ModerateinhibitorofACAT(acylcoenzymeA:cholesterolacyltransferase).
- ShowntohaveavarietyofotherBIOLOGicalactivitiessuchasantifungal,anthelmintic,insecticidal,immunomodulatoryandphytotoxicactivity.
ProductReferences
- Acomparisonofbeauvericin,enniatinandvalinomycinascalciumtransportingagentsinliposomesandchromatophores:R.C.Prince,etal.;BBRC59,697(1974)
- Inhibitionofacyl-CoA:Cholesterolacyltransferaseactivitybycyclodepsipeptideantibiotics:H.Tomoda,etal.;J.Antibiot.(Tokyo)45,1626(1992)
- Investigationoftheelectrophysiologicalpropertiesofenniatins:M.Kamyar,etal.;Arch.Biochem.Biophys.429,215(2004)
- CytotoxicityofenniatinsA,A1,B,B1,B2andB3fromFusariumavenaceum:L.Ivanova,etal.;Toxicon47,868(2006)
- Enniatinexertsp53-dependentcytostaticandp53-independentcytotoxicactivitiesagainsthumancancercells:R.Dornetshuber,etal.;Chem.Res.Toxicol.20,465(2007)
- EmergingFusarium-mycotoxinsfusaproliferin,beauvericin,enniatins,andmoniliformin-areview:M.Jestoi;Crit.Rev.FoodSci.Nutr.48,21(2008)
- OxidativestressandDNAinteractionsarenotinvolvedinEnniatin-andBeauvericin-mediatedapoptosisinduction:R.Dornetshuber,etal.;Mol.Nutr.FoodRes.53,1112(2009)
- EnniatinsA1,BandB1fromanendophyticstrainofFusariumtricinctuminduceapoptoticcelldeathinH4IIEhepatomacellsaccompaniedbyinhibitionofERKphosphorylation:W.Waetjen,etal.;Mol.Nutr.FoodRes.53,431(2009)
- ToxigenicityofenniatinsfromWesternAustralianFusariumspeciestobrineshrimp(Artemiafranciscana):D.C.Tan,etal.;Toxicon57,817(2011)
- Revisitingtheenniatins:areviewoftheirisolation,biosynthesis,structuredeterminationandbiologicalactivities:A.A.Sy-Cordero,etal.;J.Antibiot.65,541(2012)
- QuantitativedeterminationoftheFusariummycotoxinsbeauvericin,enniatinA,A1,BandB1inpigplasmausinghighperformanceliquidchromatography-tandemmassspectrometry:M.Devreese,etal.;Talanta106,212(2013)
- ApreliminarystudyinWistarratswithenniatinAcontaminatedfeed:L.Manyes,etal.;Toxicol.Mech.Methods24,179(2014)
- EvaluationofimmunologiceffectofEnniatinAandquantitativedeterminationinfeces,urineandserumontreatedWistarrats:C.Juan,etal.;Toxicon87,45(2014)
- EnniatinA1,enniatinB1andbeauvericinonHepG2:Evaluationoftoxiceffects:A.Juan-Garcia,etal.;FoodChem.Toxicol.84,188(2015)
品牌介绍
Adipogen公司由三个子公司组成，分别是Adipogen,Inc.(韩国),AdipogenSA(瑞士)和 AdipogenCorporation(美国圣地亚哥)。总部设在美国，运营总部在瑞士利斯塔尔。Adipogen公司专门从事生命科学研究试剂的开发，如癌症、免疫、炎症、代谢疾病（糖尿病、肥胖）、干细胞和神经退行性疾病等领域。其重点关注开发创新优质的ELISA试剂盒。另外，也可提供抗体和蛋白产品，Adipogen拥有自己的化学实验室，致力于开发创新型小分子化合物。
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