脂肪原/棘霉素/BVT-0267-M005/5 mg
商品编号：
BVT-0267-M005
品牌：
Adipogen Inc
市场价：
¥6800.00
美元价：
4080.00
产品分类：
其他试剂
公司分类：
Other_reagents
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
| ProductDetails | |
|---|---|
| Synonyms | QuinomycinA |
| ProductType | Chemical |
| Properties | |
| Formula | C51H64N12O12S2 |
| MW | 1101.3 |
| MerckIndex | 14:3497 |
| CAS | 512-64-1 |
| RTECS | JW5250000 |
| Source/HostChemicals | IsolatedfromStreptomycesechinatus(DSM40013). |
| PurityChemicals | ≥98%(HPLC) |
| Appearance | Whitetooff-whitesolid. |
| Solubility | Solubleinacetone,DMSO,methanol,dichloromethaneorethylacetate. |
| Identity | Determinedby1H-NMR. |
| Declaration | ManufacturedbyBioViotica. |
| OtherProductData | Containstracesofwater. |
| InChiKey | AUJXLBOHYWTPFV-UHFFFAOYSA-N |
| ShippingandHandling | |
| Shipping | AMBIENT |
| ShortTermStorage | +4°C |
| LongTermStorage | -20°C |
| HandlingAdvice | Hygroscopic. |
| Use/StABIlity | Stableforatleast1yearafterreceiptwhenstoredat-20°C. Afterreconstitutionprotectfromlightat-20°C. |
| Documents | |
| MSDS |  DownloadPDF |
| ProductSpecificationSheet | |
| Datasheet | DownloadPDF |
- Antibiotic.
- Antitumorcompound.
- Powerful,selectiveinhibitorofnucleicacidsynthesisinvitro.
- Potenthypoxia-inducIBLefactor1(HIF-1)DNAbindingactivityinhibitor.
- Apoptosisinducer.
- Antibacterial,antifungalandantiviral.
ProductReferences
- A"quinoxalineantibiotic"similartothetriostins,q.v.:I.Kuroya,etal.;J.Antibiot.14A,324(1961)
- IdentityoflevomycinandquinomycinA(echimomycin):K.Katagiri,etal.;J.Antibiot.15,273(1962)
- Themodeofactionofquinoxalineantibiotics.InteractionofquinomycinAwithdeoxyribonucleicacid:K.Sato,etal.;J.Antibiot.20,270(1967)
- EchinomycinbindingsitesonDNA:M.M.VanDyke&P.B.Dervan;Science225,1122(1984)
- Sequence-specificbindingofechinomycintoDNA:evidenceforconformationalchangesaffectingflankingsequences:C.M.Low,etal.;Nucl.AcidsRes.12,4865(1984)
- KineticevidencethatechinomycinmigratesbetweenpotentialDNAbindingsites:K.R.Fox&M.J.Waring;Nucl.AcidsRes.13,595(1985)
- EffectofechinomycinonDNAmethylation:R.L.Adams&A.Rinaldi;FEBSLett.215,266(1987)
- EchinomycinandanovelanalogueinduceapoptosisofHT-29cellsviatheactivationofMAPkinasespathway:J.Y.Park,etal.;Pharmacol.Res.50,201(2004)
- EchinomycininhibitschromosomalDNAreplicationandembryonicdevelopmentinvertebrates:L.G.Mayetal.;Nucl.AcidsRes.32,65(2004)
- Echinomycin,asmall-moleculeinhibitorofhypoxia-induciblefactor-1DNA-bindingactivity:D.Kong,etal.;CancerRes.65,9047(2005)
- MolecularsignalingcascadeinDNAbisintercalator,echinomycin-inducedapoptosisofHT-29cells:evidenceoftheapoptoticprocessviaactivationofthecytochromec-ERK-caspase-3pathway:J.Y.Park,etal.;Int.J.Biochem.CellBiol.38,244(2006)
- SynergisticeffectsofCoCl(2)andROCKinhibitiononmesenchymalstemcelldifferentiationintoneuron-likecells:E.Pacary,etal.;J.CellSci.119,2667(2006)
- Interactionofanechinomycin-DNAcomplexwithmanganeseions:R.Pfoh,etal.;ActaCryst.F65,660(2009)
- Recentdevelopmentsinbisintercalatornaturalproducts:O.E.Zolova,etal.;Biopolymers93,777(2010)
品牌介绍
Adipogen公司由三个子公司组成，分别是Adipogen,Inc.(韩国),AdipogenSA(瑞士)和 AdipogenCorporation(美国圣地亚哥)。总部设在美国，运营总部在瑞士利斯塔尔。Adipogen公司专门从事生命科学研究试剂的开发，如癌症、免疫、炎症、代谢疾病（糖尿病、肥胖）、干细胞和神经退行性疾病等领域。其重点关注开发创新优质的ELISA试剂盒。另外，也可提供抗体和蛋白产品，Adipogen拥有自己的化学实验室，致力于开发创新型小分子化合物。
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