Adipogen/Dynasore/AG-CR1-0045-M025/25 mg
商品编号：
AG-CR1-0045-M025
品牌：
Adipogen Inc
市场价：
¥3100.00
美元价：
1860.00
产品分类：
其他试剂
公司分类：
Other_reagents
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
| Product Details | |
|---|---|
| Synonyms |
3-Hydroxy-naphthalene-2-carboxylic acid (3,4-dihydroxy-benzyl- idene)-hydrazide . 0.5H2O |
| Product Type | Chemical |
| Properties | |
| Formula | C18H14N2O4 . 0.5H2O |
| MW | 322.3 . 9.0 |
| CAS |
304448-55-3 (free base) 1202867-00-2 (x H2O) |
| Purity Chemicals | ≥98% (NMR) |
| Appearance | Off-white solid. |
| Solubility | Soluble in 100% ethanol (1 mg/ml) or DMSO (10 mg/ml); insoluble in water. |
| Other Product Data | Stock solutions are stable for up to 3 months when stored at -20°C. |
| InChi Key | SYNDQCRDGGCQRZ-VXLYETTFSA-N |
| Shipping and Handling | |
| Shipping | AMBIENT |
| Short Term Storage | +4°C |
| Long Term Storage | -20°C |
| Handling Advice | Protect from light. |
| Use/Stability | Stable for at least 2 years after receipt when stored at -20°C. |
| Documents | |
| MSDS |
 Download PDF |
| Product Specification Sheet | |
| Datasheet |
Download PDF |
- Dynamin-1, -2 (DNM1, DNM2) and Dynamin-related protein 1 (DRP1) inhibitor [1].
- Endocytosis inhibitor [1, 2].
- Viral infection inhibitor [3].
- Destabilizes actin filaments [4].
- Inhibits entry of Trypanosoma into macrophages [5].
- Inhibitor of mitophagy.
- Inhibitor of hepatocyte lipophagy
Product References
- Dynasore, a cell-permeable inhibitor of dynamin.: E. Macia, et al. ; Dev. Cell. 10, 839 (2006)
- Use of Dynasore, the Small Molecule Inhibitor of Dynamin, in the Regulation of Endocytosis: T. Kirchhausen, et al.; Meth. Enzymol. 438, 77 (2008)
- HPV16 and BPV1 infection can be blocked by the dynamin inhibitor dynasore: C.Y. Abban, et al.; Am. J. Ther. 15, 304 (2008)
- Dynasore, a dynamin inhibitor, suppresses lamellipodia formation and cancer cell invasion by destabilizing actin filaments: H. Yamada, et al.; BBRC 390, 1142 (2009)
- Dynasore, a dynamin inhibitor, inhibits Trypanosoma cruzi entry into peritoneal macrophages: E.S. Barrias, et al.; PLoS One 5, e7764 (2010)
- Mitochondrial dynamics and mitophagy in the 6-hydroxydopamine preclinical model of Parkinson's disease: M.F. Galindo, et al.; Parkinsons Dis. 131058 (2012)
- A well-oiled machine: DNM2/dynamin 2 helps keep hepatocyte lipophagy running smoothly: RJ. Schulze & MA. McNiven; Autophagy 10, 388 (2013)
- Cadherin-6B undergoes macropinocytosis and clathrin-mediated endocytosis during cranial neural crest cell EMT: R. Padmanabhan & L.A. Taneyhill; J. Cell Sci. 128, 1773 (2015)
品牌介绍
Adipogen公司由三个子公司组成，分别是Adipogen,Inc.(韩国),AdipogenSA(瑞士)和 AdipogenCorporation(美国圣地亚哥)。总部设在美国，运营总部在瑞士利斯塔尔。Adipogen公司专门从事生命科学研究试剂的开发，如癌症、免疫、炎症、代谢疾病（糖尿病、肥胖）、干细胞和神经退行性疾病等领域。其重点关注开发创新优质的ELISA试剂盒。另外，也可提供抗体和蛋白产品，Adipogen拥有自己的化学实验室，致力于开发创新型小分子化合物。
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