Adipogen/Dihydroartemisinin/AG-CN2-0468-M250/250 mg
商品编号：
AG-CN2-0468-M250
品牌：
Adipogen Inc
市场价：
¥1900.00
美元价：
1140.00
产品分类：
其他试剂
公司分类：
Other_reagents
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
| Product Details | |
|---|---|
| Synonyms | Dihydroqinghaosu; Artenimol |
| Product Type | Chemical |
| Properties | |
| Formula | C15H24O5 |
| MW | 284.3 |
| CAS | 71939-50-9 |
| RTECS | KD4165550 |
| Source/Host Chemicals | Isolated from Artemisia annua. |
| Purity Chemicals | ≥98% (HPLC) |
| Appearance | White solid. |
| Solubility | Soluble in DMSO or ethanol. |
| InChi Key | BJDCWCLMFKKGEE-ISOSDAIHSA-N |
| Shipping and Handling | |
| Shipping | AMBIENT |
| Short Term Storage | +4°C |
| Long Term Storage | +4°C |
| Handling Advice |
Keep cool and dry. Protect from light. Protect from moisture and oxygen. |
| Use/Stability | Stable for at least 1 year after receipt when stored at +4°C. |
| Documents | |
| MSDS |
 Download PDF |
| Product Specification Sheet | |
| Datasheet |
Download PDF |
- Active metabolite of artemisinin.
- Anti-malaria (Plasmodium).
- Anti-schistosoma.
- Apoptosis inducer.
- Anti-cancer.
- Anti-inflammatory
- Inhibits production of tumor necrosis factor-alpha (TNF-α), interleukin-6 (IL-6), monocyte chemotactic protein-1 (MCP-1) and nitric oxide (NO).
- Autophagy inducer.
- Functional ARX inhibitor.
- Enhancer of GABAA signalling.
- Targets Gephyrin.
Product References
- Qinghaosu (artemisinin): an antimalarial drug from China: D.L. Klayman; Science 228, 1049 (1985)
- Comparison of in vivo and in vitro antimalarial activity of artemisinin, dihydroartemisinin and sodium artesunate in the Plasmodium berghei-rodent model: C. J. Janse, et al.; Int. J. Parasitol. 24, 589 (1994)
- The development of the antimalarial drugs with new type of chemical structure--qinghaosu and dihydroqinghaosu: Y. Tu; SE Asian J. Trop. Med. Publ. Health 35, 250 (2004)
- Artemisinin induces apoptosis in human cancer cells: N.P. Singh & H.C. Lai; Anticancer Res. 24, 2277 (2004)
- Artemisinin attenuates lipopolysaccharide-stimulated proinflammatory responses by inhibiting NF-κB pathway in microglia cells: C. Zhu, et al.; PLoS One 7, e35125 (2012)
- In vivo activity of dihydroartemisinin against Schistosoma mansoni schistosomula in mice: H.J. Li, et al.; SE Asian J. Trop. Med. Publ. Health 44, 379 (2013)
- Differential effect of artemisinin against cancer cell lines: M. Tilaoui, et al.; Nat. Prod. Bioprospect. 4, 189 (2014)
- Dihydroartemisinin supresses inflammation and fibrosis in bleomycine-induced pulmonary fibrosis in rats: D. Yang, et al.; Int. J. Clin. Exp. Pathol. 8, 1270 (2015)
- Dihydroartemisinin increases temozolomide efficacy in glioma cells by inducing autophagy: Z.S. Zhang, et al.; Oncol. Lett. 10, 379 (2015)
- Artemisinins target GABAA receptor signaling and impair α cell identity: J. Li, et al.; Cell 168, 86 (2017)
品牌介绍
Adipogen公司由三个子公司组成，分别是Adipogen,Inc.(韩国),AdipogenSA(瑞士)和 AdipogenCorporation(美国圣地亚哥)。总部设在美国，运营总部在瑞士利斯塔尔。Adipogen公司专门从事生命科学研究试剂的开发，如癌症、免疫、炎症、代谢疾病（糖尿病、肥胖）、干细胞和神经退行性疾病等领域。其重点关注开发创新优质的ELISA试剂盒。另外，也可提供抗体和蛋白产品，Adipogen拥有自己的化学实验室，致力于开发创新型小分子化合物。
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