Adipogen/DETA NONOate/AG-CR1-3614-M025/25 mg
商品编号：
AG-CR1-3614-M025
品牌：
Adipogen Inc
市场价：
¥2100.00
美元价：
1260.00
产品分类：
其他试剂
公司分类：
Other_reagents
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
| ProductDetails | |
|---|---|
| Synonyms | DETA/NO;DiethylenetriamineNONOate;NOC-18;2,2"-(Hydroxynitrosohydrazono)bis-ethanamine |
| ProductType | Chemical |
| Properties | |
| Formula | C4H13N5O2 |
| MW | 163.2 |
| CAS | 146724-94-9 |
| RTECS | KH2502500 |
| PurityChemicals | ≥98% |
| Appearance | Whitetooff-whitesolid. |
| Solubility | Solubleinwater. |
| OtherProductData | UVabsorbance:252nm(ε=7.640M-1cm-1) |
| InChiKey | PAOXTYJXTPPVHU-UHFFFAOYSA-O |
| ShippingandHandling | |
| Shipping | DRYICE |
| ShortTermStorage | -20°C |
| LongTermStorage | -80°C |
| HandlingAdvice | Keepunderinertgas. Protectfrommoisture. |
| Use/StABIlity | Stableforatleast1yearafterreceiptwhenstoredat-80°C. |
| Documents | |
| MSDS |  DownloadPDF |
| ProductSpecificationSheet | |
| Datasheet | DownloadPDF |
- Nitricoxide(NO)donor.TheslowreleaseofNOallowstheuseinexperimentsinvestigatingtheeffectsofprolongedconstantNOdeliverytocellsandtissues.
- Thehalf-lifetimeis20hoursat37°Cand56hoursat22-25°Cin0.1Mphosphatebuffer,pH7.4.Liberates2molofNOpermolofparentcompound.DecompositionofNONOatesisnearlyinstantaneousatpH5.0.
ProductReferences
- Newnitricoxide-releasingzwitterionsderivedfrompolyamines:J.A.Hrabie,etal.;J.Org.Chem.58,1472(1993)
- Nitricoxide/nucleophilecomplexes:auniqueclassofnitricoxide-basedvasodilators:L.K.Keefer&D.Morley;J.Cardiovasc.Pharmacol.22,3(1993)
- IntracerebroventricularadmiNISTrationofanitricoxide-releasingcompound,NOC-18,producesthermalhyperalgesiainrats:S.Shibuta,etal.;Neurosci.Lett.187,103(1995)
- NOC,anitric-oxide-releasingcompound,inducesdosedependentapoptosisinmacrophages:M.Shimaoka,etal.;BBRC209,519(1995)
- Nitricoxide(NO)donormolecules:effectofNOreleaserateonvascularsmoothmusclecellproliferationinvitro:D.L.MoorADIan,etal.;J.Cardiovasc.Pharmacol.25,674(1995)
- NONOates(1-substituteddiazen-1-ium-1,2-diolates)asnitricoxidedonors:convenientnitricoxidedosageforms:L.K.Keefer,etal.;MethodsEnzymol.268,281(1996)
- ThenitricoxidedonorDETA-NONOatedecreasesmatrixmetalloproteinase-9expressionandactivityinrataorticsmoothmuscleandaBDominalaorticexplants:I.Sinha,etal.;Ann.Vasc.Surg.20,92(2006)
- InvitroandinvivosensitizationofSW620metastaticcoloncancercellstoCDDP-inducedapoptosisbythenitricoxidedonorDETANONOate:InvolvementofAIF:S.Huerta,etal.;NitricOxide20,182(2009)
- NeuroprotectiveeffectsofnitricoxidedonorNOC-18againstbrainischemia-inducedmitochondrialdamages:roleofPKGandPKC:O.Arandarcikaite,etal.;Neurosci.Lett.586,65(2015)
品牌介绍
Adipogen公司由三个子公司组成，分别是Adipogen,Inc.(韩国),AdipogenSA(瑞士)和 AdipogenCorporation(美国圣地亚哥)。总部设在美国，运营总部在瑞士利斯塔尔。Adipogen公司专门从事生命科学研究试剂的开发，如癌症、免疫、炎症、代谢疾病（糖尿病、肥胖）、干细胞和神经退行性疾病等领域。其重点关注开发创新优质的ELISA试剂盒。另外，也可提供抗体和蛋白产品，Adipogen拥有自己的化学实验室，致力于开发创新型小分子化合物。
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