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当前位置: 首页 > 产品中心 > Other_reagents > Adipogen/Decoyinine/BVT-0030-M001/1 mg
商品详细Adipogen/Decoyinine/BVT-0030-M001/1 mg
Adipogen/Decoyinine/BVT-0030-M001/1 mg
Adipogen/Decoyinine/BVT-0030-M001/1 mg
商品编号: BVT-0030-M001
品牌: Adipogen Inc
市场价: ¥2400.00
美元价: 1440.00
产地: 美国(厂家直采)
公司:
产品分类: 其他试剂
公司分类: Other_reagents
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍
MoreInformation
ProductDetails
SynonymsAngustmycinA;U-7984;9-(6-Deoxy-D-β-erythro-hex-5-en-2-ulofuranosyl)-adenine
ProductTypeChemical
Properties
FormulaC11H13N5O4
MW279.3
CAS2004-04-8
RTECSAU6256000
Source/HostChemicalsIsolatedfromStreptomycessp.S2113.
PurityChemicals≥98%(NMR)
AppearanceWhitetooff-whitesolid.
SolubilitySolubleinDMSO(warm),wateror100%ethanol:poorlysolubleinmethanol.
IdentityDeterminedby1H-NMR.
DeclarationManufacturedbyBioViotica.
InChiKeyUZSSGAOAYPICBZ-SOCHQFKDSA-N
ShippingandHandling
ShippingAMBIENT
ShortTermStorage+4°C
LongTermStorage-20°C
HandlingAdviceProtectfromlightwheninsolution.
Use/StABIlityStableforatleast1yearafterreceiptwhenstoredat-20°C.
Afterreconstitutionprotectfromlightat-20°C.
Documents
MSDSDownloadPDF
ProductSpecificationSheet
DatasheetDownloadPDF
  • Nucleosideantibiotic.
  • Antitumorcompound.
  • Xanthosinemonophosphate(XMP)aminaseinhibitor.
  • RNAsynthesisinhibitor.
  • SpecificGMPsynthaseinhibitor.
  • ReducesintracellularGTPlevels.
ProductReferences
  1. Studiesonanewantibiotic,angustmycin:H.Sakai,etal.;J.Antibiot.7,116(1954)
  2. Studiesonanewantibiotic,angustmycin.I:H.Yuntsen,etal.;J.Antibiot.7,113(1954)
  3. Studiesonangustmycin.III:H.Yuntsen,etal.;J.Antibiot.9,195(1956)
  4. Onthestudiesofangustmycins.VI.ChemicalstructureofangustmycinA:H.Yuntsen;J.Antibiot.11,79(1958)
  5. Purinenucleosides.XXII.ThesynthesisofangustmycinA(decoyinine)andrelatedunsaturatednucleosides:J.R.McCarthy,Jr.,etal.;J.Am.Chem.Soc.90,4993(1968)
  6. Effectsofseveraltumor-inhibitoryantibioticsonimmunologicalresponses:H.Yamaki,etal.;J.Antibiot.22,315(1969)
  7. Halosugarnucleosides.5.SynthesisofangustmycinAandsomebaseanalogues:E.J.Prisbe,etal.;J.Org.Chem.41,1836(1976)
  8. AdecreaseinGTPcontentisassociatedwithaerialmyceliumformationinStreptomycesMA406-A-1:K.Ochi;J.Gen.Microbiol.132,299(1986)
  9. ExtracellularcontrolofsporeformationinBacillussubtilis:A.D.Grossman&R.Losick;PNAS85,4369(1988)
  10. Nucleosideantibiotics:structure,BIOLOGicalactivity,andbiosynthesis:K.Isono;J.Antibiot.41,1711(1988)
  11. Atargetforcarbonsource-dependentnegativeregulationofthecitBpromoterofBacillussubtilis:A.Fouret&A.L.Sonenshein;J.Bacteriol.172,835(1990)
  12. SporulationofStreptomycesvenezuelaeinsubmergedcultures:M.A.Glazebrook,etal.;J.Gen.Microbiol.136,581(1990)
  13. ConformationalstudiesonsomeCl"-branchedbeta-D-nucleosidesby1H-NMRspectroscopyandmolecularmechanicscalculations:J.Plavec,etal.;J.Biochem.Biophys.Meth.26,317(1993)
  14. BiochemicalcharacterizationofhumanGMPsynthetase:J.Nakamura&L.Lou;J.Biol.Chem.270,7347(1995)
  15. Guaninenucleotidesguanosine5"-diphosphate3"-diphosphateandGTPco-operativelyregulatetheproductionofanantibioticbacilysininBacillussubtilis:T.Inaoka,etal.;J.Biol.Chem.278,2169(2003)
  16. ExpressionofkinAandkinBofBacillussubtilis,necessaryforsporulationinitiation,isunderpositivestringenttranscriptioncontrol:S.Tojo,etal.;J.Bacteriol.195,1656(2013)
  17. PharmacologicaltargetingofguanosinemonophosphatesynthasesuppressesmelanomacellinvasionandtumOrigenicity:A.Bianchi-Smiraglia,etal.;CellDeathDiffer.22,1858(2015)
品牌介绍
Adipogen公司由三个子公司组成,分别是Adipogen,Inc.(韩国),AdipogenSA(瑞士)和 AdipogenCorporation(美国圣地亚哥)。总部设在美国,运营总部在瑞士利斯塔尔。Adipogen公司专门从事生命科学研究试剂的开发,如癌症、免疫、炎症、代谢疾病(糖尿病、肥胖)、干细胞和神经退行性疾病等领域。其重点关注开发创新优质的ELISA试剂盒。另外,也可提供抗体和蛋白产品,Adipogen拥有自己的化学实验室,致力于开发创新型小分子化合物。