Adipogen/Debromohymenialdisine/AG-CN2-0068-C100/100 µg
商品编号：
AG-CN2-0068-C100
品牌：
Adipogen Inc
市场价：
¥1900.00
美元价：
1140.00
产品分类：
其他试剂
公司分类：
Other_reagents
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
| ProductDetails | |
|---|---|
| Synonyms | DBH;DBHA-SKF;SKF108753 |
| ProductType | Chemical |
| Properties | |
| Formula | C11H11N5O2 |
| MW | 245.2 |
| CAS | 75593-17-8and125118-55-0 |
| Source/HostChemicals | IsolatedfromspongeAxinellacarteri. |
| PurityChemicals | ≥95%(HPLC) |
| Appearance | Yellowsolid. |
| Solubility | SolubleinDMSO,ethanolormethanol. |
| Identity | Determinedby1H-NMRandMS. |
| InChiKey | JYRJOQGKGMHTOO-VURMDHGXSA-N |
| ShippingandHandling | |
| Shipping | AMBIENT |
| ShortTermStorage | +4°C |
| LongTermStorage | -20°C |
| HandlingAdvice | Keepcoolanddry. Keepunderinertgas. Protectfromlight. |
| Use/StABIlity | Stableforatleast2yearsafterreceiptwhenstoredat-20°C. |
| Documents | |
| MSDS |  DownloadPDF |
| ProductSpecificationSheet | |
| Datasheet | DownloadPDF |
- ProteinkinaseC(PKC)inhibitor.InhibitstheATPbindingsite[1].
- Cytotoxicandinsecticidal[2].
- G2DNAdamagecheckpointinhibitor.Checkpointkinases1(Chk1)and2(Chk2)inhibitor[3,4,6].
- Doesnotinhibitataxia-telangiectasiamutated(ATM)orATM-Rad3-relatedproteins[3,4].
- MAPkinasekinase1(MEK-1)inhibitor[5].
- Interleukin-1(IL-1)inhibitor.Anti-osteoarthritic[7].
- Potentialanti-Alzheimeragent[7].
ProductReferences
- EffectsofaproteinkinaseCinhibitor(PKCI)onthedevelopmentofadjuvant-inducedarthritis(AA)inrats:M.DiMartino,etal.;Inflamm.Res.44,S123(1995)
- BioactivealkaloidsfromthetropicalmarinespongeAxinellacarteri:A.Supriyono,etal.;Z.Naturforsch.C50,669(1995)
- InhibitionoftheG2DNAdamagecheckpointandofproteinkinasesChk1andChk2bythemarinespongealkaloiddebromohymenialdisine:D.Curman,etal.;J.Biol.Chem.276,17914(2001)
- G2DNAdamagecheckpointinhibitionandantimitoticactivityof13-hydroxy-15-oxozoapatlin:N.T.Rundle,etal.;J.Biol.Chem.276,48231(2001)
- AldisinealkaloidsfromthePhilippinespongeStylissamassaarepotentinhibitorsofmitogen-activatedproteinkinasekinase-1(MEK-1):D.Tasdemir,etal.;J.Med.Chem.45,529(2002)
- G2checkpointabrogatorsasanticancerdrugs:T.Kawabe;Mol.CancerTher.3,513(2004)
- CellularlocalizationofdebromohymenialdisineandhymenialdisineinthemarinespongeAxinellasp.usinganewlydevelopedcellpurificationprotocol:Y.F.Song,etal.;Mar.Biotechnol.13,868(2011)
品牌介绍
Adipogen公司由三个子公司组成，分别是Adipogen,Inc.(韩国),AdipogenSA(瑞士)和 AdipogenCorporation(美国圣地亚哥)。总部设在美国，运营总部在瑞士利斯塔尔。Adipogen公司专门从事生命科学研究试剂的开发，如癌症、免疫、炎症、代谢疾病（糖尿病、肥胖）、干细胞和神经退行性疾病等领域。其重点关注开发创新优质的ELISA试剂盒。另外，也可提供抗体和蛋白产品，Adipogen拥有自己的化学实验室，致力于开发创新型小分子化合物。
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