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Adipogen/D-<em>erythro</em>-Dihydrosphingosine 1-phosphate/AG-CR1-0005-M001/1 mg
Adipogen/D-<em>erythro</em>-Dihydrosphingosine 1-phosphate/AG-CR1-0005-M001/1 mg
商品编号：
AG-CR1-0005-M001
品牌：
Adipogen Inc
市场价：
¥1800.00
美元价：
1080.00
产品分类：
其他试剂
公司分类：
Other_reagents
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
| ProductDetails | |
|---|---|
| Synonyms | (2S,3R)-Dihydro-sphingosine1-phosphate;Dihydro-S1P;dhS1P;HSPP |
| ProductType | Chemical |
| Properties | |
| Formula | C18H40NO5P |
| MW | 381.5 |
| CAS | 19794-97-9 |
| PurityChemicals | ≥98%(NMR) |
| Appearance | Whitetooff-whitesolid. |
| Solubility | Solubleinmethanol/THF/water(60/30/10)(0.5mg/ml).SlightlysolubleinDMSO,methanoloraceticacid. |
| OtherProductData | Fordeliveryofdihydrosphingosine1-phosphate(HSPP)tocells,preparea125μMstockin4mg/mlBSAasfollows:DissolveHSPPinmethanol/THF/water(60/30/10)(0.5mg/ml).Thismayrequireboiling(75°C),withoccasionalreplacementofevaporatedmethanol.Crushingofsolidpriortoadditionofsolventandcrushingandstirringduringheatingishelpful.Aliquotdesiredamountsofstocksolutiontotubes.Evaporatethesolventwithastreamofnitrogen,swirlingtodepositathinfilmofHSPPontheinsideofthetube.Aliquotsmaybestoredat-20°Catthispointordissolvedwithenough4mg/mlBSA(fattyacidfreebovineserumalbumininwater;37°C,30min.withrepeatedvortexing)tomake125μMstocksolution.Stocksolutionsarestableforupto 3monthswhenstoredat-20°C. |
| InChiKey | YHEDRJPUIRMZMP-ZWKOTPCHSA-N |
| ShippingandHandling | |
| Shipping | AMBIENT |
| ShortTermStorage | +4°C |
| LongTermStorage | -20°C |
| Use/StABIlity | Stableforatleast2yearsafterreceiptwhenstoredat-20°C. |
| Documents | |
| MSDS |  DownloadPDF |
| ProductSpecificationSheet | |
| Datasheet | DownloadPDF |
- Saturatedanalogofsphingosine1-phosphate(1-SP1).
- Ligandforsphingosine1-phosphate(S1P/EDG)receptors[1,3].
- Negativecontrolforintracellulareffectsofsphingosine1-phosphate[1].
- Induceschemotaxis[2].
- Antifibrotic[4].
ProductReferences
- Dualactionsofsphingosine-1-phosphate:extracellularthroughtheGi-coupledreceptorEdg-1andintracellulartoregulateproliferationandsurvival:J.R.vanBrocklyn,etal.;J.CellBiol.142,229(1998)
- Sphingosine1-phosphatestimulatescellmigrationthroughaG(i)-coupledcellsurfacereceptor.Potentialinvolvementinangiogenesis:F.Wang,etal.;JBC274,35343(1999)
- Sphingosine1-phosphate-inducedcellroundingandneuriteretractionaremediatedbytheGprotein-coupledreceptorH218:J.R.vanBrocklyn,etal.JBC274,4626(1999)
- Dihydrosphingosine1-phosphatehasapotentantifibroticeffectinsclerodermafibroblastsvianormalizationofphosphataseandtensinhomologlevels:ArthritisRheum.62,2117(2010)
品牌介绍
Adipogen公司由三个子公司组成，分别是Adipogen,Inc.(韩国),AdipogenSA(瑞士)和 AdipogenCorporation(美国圣地亚哥)。总部设在美国，运营总部在瑞士利斯塔尔。Adipogen公司专门从事生命科学研究试剂的开发，如癌症、免疫、炎症、代谢疾病（糖尿病、肥胖）、干细胞和神经退行性疾病等领域。其重点关注开发创新优质的ELISA试剂盒。另外，也可提供抗体和蛋白产品，Adipogen拥有自己的化学实验室，致力于开发创新型小分子化合物。
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