Adipogen/Cytostatin/AG-CN2-0093-C250/250 µg
商品编号：
AG-CN2-0093-C250
品牌：
Adipogen Inc
市场价：
¥5400.00
美元价：
3240.00
产品分类：
其他试剂
公司分类：
Other_reagents
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
| ProductDetails | |
|---|---|
| Synonyms | 5,6-Dihydro-6-(6-hydroxy-1,5-dimethyl-4-(phosphonooxy)-7,9,11-tridecatrienyl)-5-methyl-2H-pyran-2-one |
| ProductType | Chemical |
| Properties | |
| Formula | C21H32NaO7P |
| MW | 450.4 |
| CAS | 457070-06-3|682329-63-1(freebase) |
| Source/HostChemicals | IsolatedfromStreptomyces sp.MJ654-NF4. |
| PurityChemicals | ≥75%(HPLC) |
| Appearance | Yellowishpowder. |
| Solubility | Solubleinmethanol,chloroform,ethylacetate,DMSOorwater. |
| Declaration | ManufacturedbytheInstituteofMicrobialChemistry(BIKAKEN). |
| InChiKey | DXWSCXWALSKXSD-ZHCXJCEOSA-M |
| ShippingandHandling | |
| Shipping | BLUEICE |
| ShortTermStorage | +4°C |
| LongTermStorage | -20°C |
| HandlingAdvice | Keepcoolanddry. |
| Use/StABIlity | Stableforatleast3yearsafterreceiptwhenstoredat-20°C. |
| Documents | |
| MSDS |  DownloadPDF |
| ProductSpecificationSheet | |
| Datasheet | DownloadPDF |
- Potentandselectiveproteinphosphatase2A(PP2A)inhibitor[4-7].
- Celladhesioninhibitor[1].InhibitstheadhesionofB16melanomacellstolamininandcollagentypeIVinadosedependentmannerbutnottofibronectin[2].
- Antitumoragent.Antimetastatic[2,7].
- Apoptosisinducer[3].
ProductReferences
- Cytostatin,anovelinhibitorofcelladhesiontocomponentsofextracellularmatrixproducedbyStreptomycessp.MJ654-NF4.I.Taxonomy,fermentation,isolationandBIOLOGicalactivities:M.Amemiya,etal.;J.Antibiot.47,536(1994)
- InhibitoryeffectofcytostatinonspontaneouslungmetastasesofB16-BL6melanomacells:T.Masuda,etal.;J.Antibiot.48,528(1995)
- Screeningforapoptosisinducersinmicrobialproductsandinductionofapoptosisbycytostatin:K.Yamazaki,etal.;J.Antibiot.48,1138(1995)
- Cytostatin,aninhibitorofcelladhesiontoextracellularmatrix,selectivelyinhibitsproteinphosphatase2A:M.Kawada,etal.;Biochim.Biophys.Acta1452,209(1999)
- Small-moleculeinhibitorsofSer/Thrproteinphosphatases:specificity,useandcommonformsofabuse:M.R.Swingle,etal.;MethodsMol.Biol.365,23(2007)
- Structure-activityrelationshipstudiesoffostriecin,cytostatin,andkeyanalogs,withPP1,PP2A,PP5,and(beta12-beta13)-chimeras(PP1/PP2AandPP5/PP2A),providefurtherinsightintotheinhibitoryactionsoffostriecinfamilyinhibitors:M.R.Swingle,etal.;J.Pharmacol.Exp.Ther.331,45(2009)
- RubratoxinAspecificallyandpotentlyinhibitsproteinphosphatase2Aandsuppressescancermetastasis:S.Wada,etal.;CancerSci.101,743(2010)
品牌介绍
Adipogen公司由三个子公司组成，分别是Adipogen,Inc.(韩国),AdipogenSA(瑞士)和 AdipogenCorporation(美国圣地亚哥)。总部设在美国，运营总部在瑞士利斯塔尔。Adipogen公司专门从事生命科学研究试剂的开发，如癌症、免疫、炎症、代谢疾病（糖尿病、肥胖）、干细胞和神经退行性疾病等领域。其重点关注开发创新优质的ELISA试剂盒。另外，也可提供抗体和蛋白产品，Adipogen拥有自己的化学实验室，致力于开发创新型小分子化合物。
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