脂肪原/康夫菌素/AG-CN2-0465-C050/50µg
商品编号：
AG-CN2-0465-C050
品牌：
Adipogen Inc
市场价：
¥18600.00
美元价：
11160.00
产品分类：
其他试剂
公司分类：
Other_reagents
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
| ProductDetails | |
|---|---|
| Synonyms | CVX |
| ProductType | Chemical |
| Properties | |
| MW | ~84kDa |
| CAS | 37206-04-5 |
| Source/HostChemicals | IsolatedfromCrotalusdurissusterrificussnakevenom. |
| PurityChemicals | Partiallypurifiedbymulti-stepchromatography. |
| Appearance | Lyophilized. |
| Solubility | Solubleinorganicbuffer(HEPES). |
| Reconstitution | Reconstitutein10mMHEPESbuffer,pH7.2.(WerecommendaddingacarrierproteinsuchasBSAtothereconstitutionbufferandanysubsequentdilutionbufferstopreventabsorptiononplasticsurfaces.) |
| BIOLOGicalActivity | <50ng/ml(minimalconcentrationtoinducemaximumactivationofwashedhumanplatelets). |
| OtherProductData | Stocksolutionsarestablefor8hoursat+20°C,for2daysat+4°Corfor1monthwhenstoredat-80°C. |
| ShippingandHandling | |
| Shipping | AMBIENT |
| ShortTermStorage | +4°C |
| LongTermStorage | -20°C |
| HandlingAdvice | Afteropening,preparealiquotsandstoreat-80°C. Avoidfreeze/thawcycles. Protectfromlightandmoisture. |
| Use/StABIlity | Stableforatleast2yearsafterreceiptwhenstoredat-20°C. |
| Documents | |
| Protocols |  DownloadPDF |
| MSDS | DownloadPDF |
| ProductSpecificationSheet | |
| Datasheet | DownloadPDF |
- GlycoproteinGPVIreceptoragoNIST.Canbeusedforstudiesonplateletreceptors.
- ActivatesmammalianplateletsviabindingandclusteringofGPVI-receptorsunderphysiologicalconditions.OccupationandclusteringofGPVIactivatesSrcfamilykinases,phosphorylatesFcreceptorγ-chainandactivatesp72SYKthatiscriticalfordownstreamactivationofplatelets.
- Causescardiovascularandrespiratorydisturbances.
- Prostaglandinsarestronginhibitorsofconvulxin-inducedaggregation.
- HeterodimericC-typelectin.Disulfidelinkedheterodimerconsistingofhomologousαandβchains.Theheterodimersareadditionallylinkedbydisulfidebridgestoformcyclicα(4)β(4)heterotetramers.
ProductReferences
- Convulxin,anewtoxinfromthevenomoftheSouthAmericanrattlesnakeCrotalusdurissusterrificus:J.Prado-Franceschi&O.V.Brazil;Toxicon19,875(1981)
- Convulxin,apotentplatelet-aggregatingproteinfromCrotalusdurissusterrificusvenom,specificallybindstoplatelets:I.M.Francischetti,etal.;Toxicon35,1217(1997)
- Plateletactivationandsignaltransductionbyconvulxin,aC-typelectinfromCrotalusdurissusterrificus(tropicalrattlesnake)venomviathep62/GPVIcollagenreceptor:J.Polgar,etal.;J.Biol.Chem.272,13576(1997)
- Convulxin-inducedplateletadhesionandaggregation:involvementofglycoproteinsVIandIaIIa:M.Jandrot-Perrus,etal.;Platelets9,207(1998)
- Collagen,convulxin,andthrombinstimulateaggregation-independenttyrosinephosphorylationofCD31inplatelets.EvidencefortheinvolvementofSrcfamilykinases:M.Cicmil,etal.;J.Biol.Chem.275,27339(2000)
- SignallingeventsunderlyingplateletaggregationinducedbytheglycoproteinVIagonistconvulxin:B.T.Atkinson,etal.;Eur.J.Biochem.268,5242(2001)
- ConvulxinbindingtoplateletreceptorGPVI:competitionwithcollagenrelatedpeptides:F.Niedergang,etal.;BBRC273,246(2002)
- Convulxinbindstonative,humanglycoproteinIbalpha:S.Kanaji,etal.;J.Biol.Chem.278,39452(2003)
品牌介绍
Adipogen公司由三个子公司组成，分别是Adipogen,Inc.(韩国),AdipogenSA(瑞士)和 AdipogenCorporation(美国圣地亚哥)。总部设在美国，运营总部在瑞士利斯塔尔。Adipogen公司专门从事生命科学研究试剂的开发，如癌症、免疫、炎症、代谢疾病（糖尿病、肥胖）、干细胞和神经退行性疾病等领域。其重点关注开发创新优质的ELISA试剂盒。另外，也可提供抗体和蛋白产品，Adipogen拥有自己的化学实验室，致力于开发创新型小分子化合物。
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