Adipogen/Colistin sulfate (USP Grade)/AG-CN2-0065-G005/5 g
商品编号：
AG-CN2-0065-G005
品牌：
Adipogen Inc
市场价：
¥5600.00
美元价：
3360.00
产品分类：
其他试剂
公司分类：
Other_reagents
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
| ProductDetails | |
|---|---|
| Synonyms | PolymyxinE;Belcomycin;Colimycin |
| ProductType | Chemical |
| Properties | |
| Formula | 2(C52H98N16O13).5(H2SO4)(unspec.) |
| MW | 2801.7 |
| CAS | 1264-72-8 |
| RTECS | TR1500000 |
| Source/HostChemicals | IsolatedfromBacilluspolymyxa. |
| PurityChemicals | Mixture(primarlycolistinAandB). |
| Appearance | Whitetooff-whitepowder. |
| Solubility | Solubleinwater. |
| BIOLOGicalActivity | Potency(drybasis)≥15000U/mg |
| InChiKey | YKQOSKADJPQZHB-QNPLFGSASA-N |
| ShippingandHandling | |
| Shipping | AMBIENT |
| ShortTermStorage | +4°C |
| LongTermStorage | +4°C |
| HandlingAdvice | Keepcoolanddry. |
| Use/StABIlity | Stableforatleast2yearsafterreceiptwhenstoredat+4°C. |
| Documents | |
| MSDS |  DownloadPDF |
| ProductSpecificationSheet | |
| Datasheet | DownloadPDF |
- Verypotentpolymyxinantibiotic.
- HasonlyoneaminoaciddifferencecomparedtopolymyxinB.
- Antimicrobial.
- Targetsthelipopolysaccharide(LPS)oftheoutermembraneofGram-negativebacteria.Competitivelydisplacesdivalentcations(Ca2+andMg2+)fromthenegatively-chargedphosphategroupsLPS,causingdisruptionofthemembrane.Thisincreasesthepermeabilityofthecellenvelope,leakageofcellcontents,leADIngtoapoptosisandcelldeath.
- Usedagainstmultidrug-resistantGram-negativebacterialinfections.
ProductReferences
- Antimicrobialdrugs,microorganisms,andphagocytes:P.J.vandenBroek;Rev.Infect.Dis.11,213(1989)(Review)
- PolymyxinBsulfateandcolistin:oldantibioticsforemergingmultiresistantgram-negativebacteria:M.E.Evans,etal.;Ann.Pharmacother.33,960(1999)(Review)
- Theclinicaluseofcolistininpatientswithcysticfibrosis:P.Beringer;Curr.Opin.Pulm.Med.7,434(2001)(Review)
- Updateonantimicrobialagents:newindicationsofolderagents:T.R.Pasquale&J.S.Tan;ExpertOpin.Pharmacother.6,1681(2005)(Review)
- Colistin:there-emergingantibioticformultidrug-resistantGram-negativebacterialinfections:J.Li,etal.;LancetInfect.Dis.6,589(2006)(Review)
- PolymyxinB:similaritiestoanddifferencesfromcolistin(polymyxinE):A.Kwa,etal.;ExpertRev.Anti.Infect.Ther.5,811(2007)(Review)
- Colistininthe21stcentury:R.L.Nation&J.Li;Curr.Opin.Infect.Dis.22,535(2009)(Review)
- Newinformationaboutthepolymyxin/colistinclassofantibiotics:J.Molina,etal.;ExpertOpin.Pharmacother.10,2811(2009)(Review)
- Colistin:newlessonsonanoldantibiotic:D.Yahav,etal.;Clin.Microbiol.Infect.18,18(2012)(Review)
品牌介绍
Adipogen公司由三个子公司组成，分别是Adipogen,Inc.(韩国),AdipogenSA(瑞士)和 AdipogenCorporation(美国圣地亚哥)。总部设在美国，运营总部在瑞士利斯塔尔。Adipogen公司专门从事生命科学研究试剂的开发，如癌症、免疫、炎症、代谢疾病（糖尿病、肥胖）、干细胞和神经退行性疾病等领域。其重点关注开发创新优质的ELISA试剂盒。另外，也可提供抗体和蛋白产品，Adipogen拥有自己的化学实验室，致力于开发创新型小分子化合物。
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