Adipogen/Cinnamtannin B-1/AG-CN2-0428-M005/5 mg
商品编号：
AG-CN2-0428-M005
品牌：
Adipogen Inc
市场价：
¥4800.00
美元价：
2880.00
产品分类：
其他试剂
公司分类：
Other_reagents
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
| Product Details | |
|---|---|
| Synonyms | Epicatechin-(4β→8,2β→O→7)-epicatechin-(4α→8)-epicatechin; Cinnamtannin B1; CB1 |
| Product Type | Chemical |
| Properties | |
| Formula | C45H36O18 |
| MW | 864.7 |
| CAS | 88082-60-4 |
| Source/Host Chemicals | Isolated from Laurus nobilis L. |
| Purity Chemicals | ≥95% (HPLC) |
| Appearance | Brown solid. |
| Solubility | Soluble in ethanol, methanol or a DMSO:water mixture. |
| Other Product Data | Stable in methanol solution for up to 4 weeks when stored at -20°C. |
| InChi Key | BYSRPHRKESMCPO-LQNPQWRQSA-N |
| Shipping and Handling | |
| Shipping | AMBIENT |
| Short Term Storage | +4°C |
| Long Term Storage | -20°C |
| Handling Advice |
Keep cool and dry. Keep under inert gas. Protect from light. |
| Use/Stability | Stable for at least 2 years after receipt when stored at -20°C. |
| Documents | |
| MSDS |
 Download PDF |
| Product Specification Sheet | |
| Datasheet |
Download PDF |
- A-Type proanthocyanidine.
- Selective cytotoxic agent [1].
- Potent antioxidant [2, 4, 8, 9].
- Lipid peroxidation inhibitor [2].
- Antidiabetic, with similar effects to insulin activity in adipogenesis [3].
- Free radical scavenger [4].
- Antithrombotic. Inhibits platelet aggregation [5, 6, 8].
- Apoptosis inhibitor [7, 12].
- Reduces intracellular Ca(2+) overload and ROS production [8, 10].
- Antibacterial [9].
- Cyclooxygenase-2 (COX-2) inhibitor in vitro [11].
- LDL oxidation inhibitor [13].
Product References
- Antitumor agents, 129. Tannins and related compounds as selective cytotoxic agents: Y. Kashiwada, et al.; J. Nat. Prod. 55, 1033 (1992)
- Antioxidant activity of tannin components from Vaccinium vitis-idaea L: K.Y. Ho, et al.; J. Pharm. Pharmacol. 51, 1075 (1999)
- Cinnamtannin B1 activity on adipocytes formation: M. Taher, et al.; Med. J. Malaysia 59, 97 (2004)
- Phenolic constituents in the fruits of Cinnamomum zeylanicum and their antioxidant activity: G.K. Jayaprakasha, et al.; J. Agric. Food Chem. 54, 1672 (2006)
- Characterization of the intracellular mechanisms involved in the antiaggregant properties of cinnamtannin B-1 from bay wood in human platelets: N. Ben Amor, et al.; J. Med. Chem. 50, 3937 (2007)
- Cinnamtannin B-1 from bay wood reduces abnormal intracellular Ca2+ homeostasis and platelet hyperaggregability in type 2 diabetes mellitus patients: A. Bouaziz, et al.; Arch. Biochem. Biophys. 457, 235 (2007)
- Cinnamtannin B-1 from bay wood exhibits antiapoptotic effects in human platelets: A. Bouaziz, et al.; Apoptosis 12, 489 (2007)
- Cinnamtannin B-1 as an antioxidant and platelet aggregation inhibitor: J.J. López, et al.; Life Sci. 82, 977 (2008)
- Doubly linked, A-type proanthocyanidin trimer and other constituents of Ixora coccinea leaves and their antioxidant and antibacterial properties : T.O. Idowu, et al.; Phytochemistry 71, 2092 (2010)
- Effect of cinnamtannin B-1 on cholecystokinin-8-evoked responses in mouse pancreatic acinar cells: R. Rivera-Barreno, et al.; Clin. Exp. Pharmacol. Physiol. 37, 980 (2010)
- Bioactive A-type proanthocyanidins from Cinnamomum cassia: K.B. Killday, et al.; J. Nat. Prod. 74, 1833 (2011)
- Cinnamtannin B-1 regulates cell proliferation of spinal cord astrocytes and protects the cell from oxygen-glucose-serum deprivation/reoxygenation-induced apoptosis: Z. Chi, et al.; Int. J. Mol. Sci. 14, 15827 (2013)
- Flavonoids from Lindera glauca Blume as low-density lipoprotein oxidation inhibitors: G.W. Huh, et al.; Nat. Prod. Res. 28, 831 (2014)
品牌介绍
Adipogen公司由三个子公司组成，分别是Adipogen,Inc.(韩国),AdipogenSA(瑞士)和 AdipogenCorporation(美国圣地亚哥)。总部设在美国，运营总部在瑞士利斯塔尔。Adipogen公司专门从事生命科学研究试剂的开发，如癌症、免疫、炎症、代谢疾病（糖尿病、肥胖）、干细胞和神经退行性疾病等领域。其重点关注开发创新优质的ELISA试剂盒。另外，也可提供抗体和蛋白产品，Adipogen拥有自己的化学实验室，致力于开发创新型小分子化合物。
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