Adipogen/CI-1040/SYN-1031-M005/5 mg
商品编号：
SYN-1031-M005
品牌：
Adipogen Inc
市场价：
¥1520.00
美元价：
912.00
产品分类：
其他试剂
公司分类：
Other_reagents
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
| Product Details | |
|---|---|
| Synonyms | PD-184352; CI-1040 |
| Product Type | Chemical |
| Properties | |
| Formula | C17H14ClF2IN2O2 |
| MW | 478.7 |
| CAS | 212631-79-3 |
| Purity Chemicals | ≥95% |
| Appearance | Solid. |
| Solubility | Soluble in DMSO or ethanol. |
| Declaration | Manufactured by SynKinase. |
| Other Product Data |
Target: MEK - MKK4&7 - MKK3&6 - MEK5 - MEK2 - MEK1 | Kinase Group: STE | Substrate: Serine-Threonine Click here for Original Manufacturer Product Datasheet Our product description may differ slightly from the original manufacturers product datasheet. |
| InChi Key | GFMMXOIFOQCCGU-UHFFFAOYSA-N |
| Shipping and Handling | |
| Shipping | AMBIENT |
| Short Term Storage | +4°C |
| Long Term Storage | -20°C |
| Use/Stability | Stable for at least 2 years after receipt when stored at -20°C. |
| Documents | |
| MSDS |
 Download PDF |
| Product Specification Sheet | |
| Datasheet |
Download PDF |
CI-1040 (PD184352) is an orally active, highly specific, small-molecule inhibitor of MEK1/2, which is a key component of the ERK/MAPK pathway. It has an IC(50) of 17nM.
Product References
- Synergistic induction of apoptosis by simultaneous disruption of the Bcl-2 and MEK/MAPK pathways in acute myelogenous leukemia: M. Milella, et al.; Blood 99, 3461 (2002)
品牌介绍
Adipogen公司由三个子公司组成，分别是Adipogen,Inc.(韩国),AdipogenSA(瑞士)和 AdipogenCorporation(美国圣地亚哥)。总部设在美国，运营总部在瑞士利斯塔尔。Adipogen公司专门从事生命科学研究试剂的开发，如癌症、免疫、炎症、代谢疾病（糖尿病、肥胖）、干细胞和神经退行性疾病等领域。其重点关注开发创新优质的ELISA试剂盒。另外，也可提供抗体和蛋白产品，Adipogen拥有自己的化学实验室，致力于开发创新型小分子化合物。
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