Adipogen/Cephalochromin/BVT-0440-M005/5 mg
商品编号：
BVT-0440-M005
品牌：
Adipogen Inc
市场价：
¥8400.00
美元价：
5040.00
产品分类：
其他试剂
公司分类：
Other_reagents
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
| Product Details | |
|---|---|
| Synonyms | Cefalochromin; NSC201419; NSC627953; Antibiotic Sch45752; 2,2',3,3'-Tetrahydro-5,5',6,6',8,8'-hexahydroxy-2,2'-dimethyl-9,9'-bi[4H-naphtho[2,3-b]pyran]-4,4'-dione |
| Product Type | Chemical |
| Properties | |
| Formula | C28H22O10 |
| MW | 518.5 |
| CAS | 25908-26-3 |
| Source/Host Chemicals | Isolated from Pseudoanguillospora sp. (strain 6577). |
| Purity Chemicals | ≥98% (HPLC) |
| Appearance | Orange amorphous powder. |
| Solubility | Soluble in DMSO, methanol, acetone or dichloromethane. |
| Identity | Determined by 1H-NMR, MS and CD. |
| Declaration | Manufactured by BioViotica. |
| InChi Key | FCPNXYHPAIZMNJ-UHFFFAOYSA-N |
| Shipping and Handling | |
| Shipping | AMBIENT |
| Short Term Storage | +4°C |
| Long Term Storage | -20°C |
| Handling Advice | Protect from light when in solution. |
| Use/Stability |
Stable for at least 1 year after receipt when stored at -20°C. Store solutions at -20°C in the dark. |
| Documents | |
| MSDS |
 Download PDF |
| Product Specification Sheet | |
| Datasheet |
Download PDF |
- Mycotoxin. Bis(naphtha-γ-pyrone) derivative similar to chaetochromin and ustilaginoidin [1, 3].
- Antibiotic [1].
- Antibacterial, antifungal and anti-algal compound [1, 7].
- Antitumor and cytotoxic compound [2].
- Calmodulin-sensitive PDE activity inhibitor [4].
- Inhibits NO production by activated macrophages [5].
- Selective Fabl (bacterial enoyl-acyl carrier protein (ACP) reductase) inhibitor [6].
- Inducer of G0/G1 cell cycle arrest and apoptosis in human A549 cells [8].
Product References
- Cephalochromin, dihydroiso-ustilaginoidin A and iso-ustilaginoidin A from Verticillium sp. K-113: M. Matsumoto, et al.; J. Antibiot. 28, 602 (1975)
- Cytotoxicity and antitumor activities of fungal bis(naphtho-gamma-pyrone) derivatives: K. Koyama, et al.; J. Pharmacobiodyn. 11, 630 (1988)
- The impairing effect of chaetochromin A and related mycotoxins on mitochondrial respiration: K. Kawai, et al.; Mycotoxins 33, 31-5 (1991)
- Sch 45752, an inhibitor of calmodulin-sensitive cyclic nucleotide phosphodiesterase activity: V.R. Hedge, et al.; J. Antibiot. 46, 207 (1993)
- Inhibitory effects of fungal bis(naphtho-γ-pyrone) derivatives on nitric oxide production by a murine macrophage-like cell line, RAW 264.7, activated by lipopolysaccharide and interferon-γ.: R. Ishii, et al.; Biol. Pharm. Bull. 28, 786 (2005)
- Cephalochromin, a FabI-directed antibacterial of microbial origin: C.J. Zheng, et al.; BBRC 362, 1107 (2007)
- Pseudoanguillosporin A and B: two new isochromans isolated from the edophytic fungus Pseudoanguillospora sp.: I. Kock, et al.; Eur. J. Org. Chem. 2009, 1427 (2009)
- Cephalochromin induces G0/G1 cell cycle arrest and apoptosis in A549 human non-small-cell lung cancer cells by inflicting mitochondrial disruption: C.-J. Hsiao, et al.; J. Nat. Prod. 77, 758 (2014)
品牌介绍
Adipogen公司由三个子公司组成，分别是Adipogen,Inc.(韩国),AdipogenSA(瑞士)和 AdipogenCorporation(美国圣地亚哥)。总部设在美国，运营总部在瑞士利斯塔尔。Adipogen公司专门从事生命科学研究试剂的开发，如癌症、免疫、炎症、代谢疾病（糖尿病、肥胖）、干细胞和神经退行性疾病等领域。其重点关注开发创新优质的ELISA试剂盒。另外，也可提供抗体和蛋白产品，Adipogen拥有自己的化学实验室，致力于开发创新型小分子化合物。
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