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当前位置: 首页 > 产品中心 > Other_reagents > Adipogen/Cephalochromin/BVT-0440-M001/1 mg
商品详细Adipogen/Cephalochromin/BVT-0440-M001/1 mg
Adipogen/Cephalochromin/BVT-0440-M001/1 mg
Adipogen/Cephalochromin/BVT-0440-M001/1 mg
商品编号: BVT-0440-M001
品牌: Adipogen Inc
市场价: ¥2800.00
美元价: 1680.00
产地: 美国(厂家直采)
公司:
产品分类: 其他试剂
公司分类: Other_reagents
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍
MoreInformation
ProductDetails
SynonymsCefalochromin;NSC201419;NSC627953;AntibioticSch45752;2,2",3,3"-Tetrahydro-5,5",6,6",8,8"-hexahydroxy-2,2"-dimethyl-9,9"-bi[4H-naphtho[2,3-b]pyran]-4,4"-dione
ProductTypeChemical
Properties
FormulaC28H22O10
MW518.5
CAS25908-26-3
Source/HostChemicalsIsolatedfromPseudoanguillosporasp.(strain6577).
PurityChemicals≥98%(HPLC)
AppearanceOrangeamorphouspowder.
SolubilitySolubleinDMSO,methanol,acetoneordichloromethane.
IdentityDeterminedby1H-NMR,MSandCD.
DeclarationManufacturedbyBioViotica.
InChiKeyFCPNXYHPAIZMNJ-UHFFFAOYSA-N
ShippingandHandling
ShippingAMBIENT
ShortTermStorage+4°C
LongTermStorage-20°C
HandlingAdviceProtectfromlightwheninsolution.
Use/StABIlityStableforatleast1yearafterreceiptwhenstoredat-20°C.
Storesolutionsat-20°Cinthedark.
Documents
MSDSDownloadPDF
ProductSpecificationSheet
DatasheetDownloadPDF
  • Mycotoxin.Bis(naphtha-γ-pyrone)derivativesimilartochaetochrominandustilaginoidin[1,3].
  • Antibiotic[1].
  • Antibacterial,antifungalandanti-algalcompound[1,7].
  • Antitumorandcytotoxiccompound[2].
  • Calmodulin-sensitivePDEactivityinhibitor[4].
  • InhibitsNOproductionbyactivatedmacrophages[5].
  • SelectiveFabl(bacterialenoyl-acylcarrierprotein(ACP)reductase)inhibitor[6].
  • InducerofG0/G1cellcyclearrestandapoptosisinhumanA549cells[8].
ProductReferences
  1. Cephalochromin,dihydroiso-ustilaginoidinAandiso-ustilaginoidinAfromVerticilliumsp.K-113:M.Matsumoto,etal.;J.Antibiot.28,602(1975)
  2. Cytotoxicityandantitumoractivitiesoffungalbis(naphtho-gamma-pyrone)derivatives:K.Koyama,etal.;J.Pharmacobiodyn.11,630(1988)
  3. TheimpairingeffectofchaetochrominAandrelatedmycotoxinsonmitochondrialrespiration:K.Kawai,etal.;Mycotoxins33,31-5(1991)
  4. Sch45752,aninhibitorofcalmodulin-sensitivecyclicnucleotidephosphodiesteraseactivity:V.R.Hedge,etal.;J.Antibiot.46,207(1993)
  5. Inhibitoryeffectsoffungalbis(naphtho-γ-pyrone)derivativesonnitricoxideproductionbyamurinemacrophage-likecellline,RAW264.7,activatedbylipopolysaccharideandinterferon-γ.:R.Ishii,etal.;Biol.Pharm.Bull.28,786(2005)
  6. Cephalochromin,aFabI-directedantibacterialofmicrobialorigin:C.J.Zheng,etal.;BBRC362,1107(2007)
  7. PseudoanguillosporinAandB:twonewisochromansisolatedfromtheedophyticfungusPseudoanguillosporasp.:I.Kock,etal.;Eur.J.Org.Chem.2009,1427(2009)
  8. CephalochromininducesG0/G1cellcyclearrestandapoptosisinA549humannon-small-celllungcancercellsbyinflictingmitochondrialdisruption:C.-J.Hsiao,etal.;J.Nat.Prod.77,758(2014)
品牌介绍
Adipogen公司由三个子公司组成,分别是Adipogen,Inc.(韩国),AdipogenSA(瑞士)和 AdipogenCorporation(美国圣地亚哥)。总部设在美国,运营总部在瑞士利斯塔尔。Adipogen公司专门从事生命科学研究试剂的开发,如癌症、免疫、炎症、代谢疾病(糖尿病、肥胖)、干细胞和神经退行性疾病等领域。其重点关注开发创新优质的ELISA试剂盒。另外,也可提供抗体和蛋白产品,Adipogen拥有自己的化学实验室,致力于开发创新型小分子化合物。