Adipogen/Carbamoylcholine . chloride/AG-CR1-3649-G001/1 g
商品编号：
AG-CR1-3649-G001
品牌：
Adipogen Inc
市场价：
¥1400.00
美元价：
840.00
产品分类：
其他试剂
公司分类：
Other_reagents
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
| ProductDetails | |
|---|---|
| Synonyms | Carbachol;(2-Hydroxyethyl)trimethylammoniumchloridecarbamate |
| ProductType | Chemical |
| Properties | |
| Formula | C6H15N2O2.Cl |
| MW | 147.3.35.4 |
| CAS | 51-83-2 |
| RTECS | GA0875000 |
| PurityChemicals | ≥98% |
| Appearance | Whitetoyellowcrystallinesolid. |
| Solubility | Solubleinwater,methanol,ethanolorDMSO. |
| InChiKey | AIXAANGOTKPUOY-UHFFFAOYSA-N |
| ShippingandHandling | |
| Shipping | AMBIENT |
| ShortTermStorage | +4°C |
| LongTermStorage | -20°C |
| HandlingAdvice | Hygroscopic. Keepcoolanddry. |
| Use/StABIlity | Stableforatleast2yearsafterreceiptwhenstoredat-20°C. |
| Documents | |
| MSDS |  DownloadPDF |
| ProductSpecificationSheet | |
| Datasheet | DownloadPDF |
- Acetylcholineanalogthatactivatesacetylcholinereceptors(AChR).
- Non-selectiveagoNISTofnicotinic(nAChR)andmuscarinic(mAChR)receptorsthatisresistanttotheactionofcholinesterases.
- UsedtostudyresponsesmediatedbynAChRandmAChR,includingsmoothmusclecontraction,gutmotilityandneuronalsignaling.
- Showntoinhibitapoptoticdeathofculturedneurons.
ProductReferences
- Activationofmuscariniccholinergicreceptorsblocksapoptosisofculturedcerebellargranuleneurons:G.M.Yan,etal.;Mol.Pharmacol.47,248(1995)
- Carbamoylcholinehomologs:Novelandpotentagonistsatneuronalnicotinicacetylcholinereceptors:A.A.Jensen,etal.;Mol.Pharmacol.64,865(2003)
- Thecomparativepharmacologyandup-regulationofratneuronalnicotinicreceptorsubtypebindingsitesstablyexpressedintransfectedmammaliancells:Y.Xiao&K.J.Kellar;J.Pharmacol.Exp.Ther.310,98(2004)
- DistinctpathwaysofERKactivationbythemuscarinicagonistspilocarpineandcarbacholinahumansalivarycellline:A.L.Lin,etal.;Am.J.Physiol.CellPhysiol.294,C1454(2008)
- K+AChchannelactivationwithcarbacholincreasesatrialANPrelease:D.Y.Xu,etal.;LifeSci.82,1083(2008)
- IL-17Ainduceshypo-contractionofintestinalsmoothmuscleviainductionofiNOSinmuscularismacrophages:D.Mori,etal.;J.Pharmacol.Sci.125,394(2014)
品牌介绍
Adipogen公司由三个子公司组成，分别是Adipogen,Inc.(韩国),AdipogenSA(瑞士)和 AdipogenCorporation(美国圣地亚哥)。总部设在美国，运营总部在瑞士利斯塔尔。Adipogen公司专门从事生命科学研究试剂的开发，如癌症、免疫、炎症、代谢疾病（糖尿病、肥胖）、干细胞和神经退行性疾病等领域。其重点关注开发创新优质的ELISA试剂盒。另外，也可提供抗体和蛋白产品，Adipogen拥有自己的化学实验室，致力于开发创新型小分子化合物。
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