Adipogen/Calcein-AM/CDX-C0009-M001/1 mg
商品编号：
CDX-C0009-M001
品牌：
Adipogen Inc
市场价：
¥2820.00
美元价：
1692.00
产品分类：
其他试剂
公司分类：
Other_reagents
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
| ProductDetails | |
|---|---|
| Synonyms | CAL-AM;CalceinO,O"-diacetatetetrakis(acetoxymethyl)ester;Calceinacetoxymethylester;NSC689290 |
| ProductType | Chemical |
| Properties | |
| Formula | C46H46N2O23 |
| MW | 994.86 |
| CAS | 148504-34-1 |
| Source/HostChemicals | Synthetic. |
| PurityChemicals | ≥95%(HPLC) |
| Appearance | Whitetooff-whitesolid. |
| Solubility | SolubleinDMSO. |
| Declaration | ManufacturedbyChemodex. |
| OtherProductData | ClickhereforOriginalManufacturerProductDatasheet Ourproductdescriptionmaydifferslightlyfromtheoriginalmanufacturersproductdatasheet. |
| InChiKey | XKFSBWQWNMZWFA-UHFFFAOYSA-N |
| ShippingandHandling | |
| Shipping | BLUEICE |
| ShortTermStorage | -20°C |
| LongTermStorage | -20°C |
| HandlingAdvice | Keepcoolanddry. Protectfromlightandmoisture. |
| Use/StABIlity | Stableforatleast2yearsafterreceiptwhenstoredat-20°C. |
| Documents | |
| MSDS | No |
| ProductSpecificationSheet | |
| Datasheet |  DownloadPDF |
Calcein-AMisanon-fluorescentcellpermeableandhydrophobicprobethat,uponenteringlivecells,iscleavedbyintracellularesterases,releasingthemembrane-impermeable,hydrophilic,andintenselybrightgreenfluorescentcalcein.Betterretainedbyviablecellsthanfluorescein,carboxyfluorescein,orBCECF,duetoitslowcytotoxicity.Itcanbeusedasanindicatorofcellviability(deadcellslackcytoplasmicesterases),cell-cellcommunication,cytotoxicityorchangesinintracellularcalcium,fluoride,ironormercury.Calcein-AMisaneutralsubstrateformultidrugresistance-associatedprotein1(MRP1)andmultidrugresistanceprotein3(MDR3,P-glycoprotein3)andhasbeenusedinflowcytometrystudiestoanalyzethefunctionofP-gpandMRP.Usedasacytosolicfluorophoreinmitochondrialpermeabilitystudiestoimageporetransition.Viabilityassaysusingcalceinarereliableandcorrelatewellwiththestandard51Cr-releaseassay.SpectralData:λex496nm;λem516nmin0.1MTrispH8.0.
ProductReferences
(1)N.Feller,etal.;Br.J.Cancer.72,543(1995)|(2)N.Feller,etal.;FEBSLett.368385(1995)|(3)F.Tiberghien&F.Loor;Anti-CancerDrugs7,568(1996)|(4)P.Decherchi,etal.;J.Neurosci.Methods71,205(1997)|(5)M.Essodaigui,etal.;Biochemistry37,2243(1998)|(6)J.J.Lemasters,etal.;Biochim.Biophys.Acta.1366,177(1998)|(7)J.Hynes,etal.;J.Biomol.Screen.8,264(2003)|(8)D.Bratosin,etal.;CytometryA66,78(2005)|(9)R.W.Sabnis;HandbookofBIOLOGicaldyesandstains(2010)|(10)G.Szakacs,etal.;Pathol.Oncol.Res.4,251(2016)
品牌介绍
Adipogen公司由三个子公司组成，分别是Adipogen,Inc.(韩国),AdipogenSA(瑞士)和 AdipogenCorporation(美国圣地亚哥)。总部设在美国，运营总部在瑞士利斯塔尔。Adipogen公司专门从事生命科学研究试剂的开发，如癌症、免疫、炎症、代谢疾病（糖尿病、肥胖）、干细胞和神经退行性疾病等领域。其重点关注开发创新优质的ELISA试剂盒。另外，也可提供抗体和蛋白产品，Adipogen拥有自己的化学实验室，致力于开发创新型小分子化合物。
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