Adipogen/Bradykinin/AG-CP3-0025-M025/25 mg
商品编号：
AG-CP3-0025-M025
品牌：
Adipogen Inc
市场价：
¥1840.00
美元价：
1104.00
产品分类：
其他试剂
公司分类：
Other_reagents
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
| ProductDetails | |
|---|---|
| Synonyms | H-Arg-Pro-Pro-Gly-Phe-Ser-Pro-Phe-Arg-OH.TFA |
| ProductType | Chemical |
| Properties | |
| Formula | C50H73N15O11.C2HF3O2 |
| MW | 1060.2.114.0 |
| Sequence | H-Arg-Pro-Pro-Gly-Phe-Ser-Pro-Phe-Arg-OH |
| MerckIndex | 14:1359 |
| CAS | 121283-65-6|58-82-2(freebase) |
| PurityChemicals | ≥97%(HPLC) |
| Appearance | Lyophilizedpowder. |
| Solubility | Solubleinwater(1mg/ml)or5%aceticacid. |
| InChiKey | WTRZIOCXFWDHEM-MIEKKPBHSA-N |
| ShippingandHandling | |
| Shipping | AMBIENT |
| ShortTermStorage | +4°C |
| LongTermStorage | -20°C |
| HandlingAdvice | Protectfromlight. |
| Use/StABIlity | Stableforatleast1yearafterreceiptwhenstoredat-20°C. |
| Documents | |
| MSDS |  DownloadPDF |
| ProductSpecificationSheet | |
| Datasheet | DownloadPDF |
- Pro-inflammatorypeptide,actingthroughG-protein-coupledreceptors.
- EndogenousbradykininreceptoragoNISTthatdisplaysselectivityforB2overB1receptors.
- Endogenouslyformedfollowingpathophysiologicalstimulisuchasinflammation,tissuedamageoranoxia.
- Activatorofendothelialnitricoxidesynthase(eNOS;NOSIII).Reducesbloodpressurebyinducingthereleaseofprostacyclin,nitricoxideandendothelium-derivedhyperpolarizingfactor.
- Playsanimportantroleintheregulationoffluidandelectrolytebalance,non-vascularsmoothmusclecontraction,vasodilationandcapillarypermeability.
ProductReferences
- Actionsofpurebradykinin:D.F.Elliott,etal.;J.Physiol.153,473(1960)
- Thediscoveryofnitricoxideastheendogenousnitrovasodilator:S.Moncada,etal.;Hypertension12,365(1988)
- BradykininandATPstimulateL-arginineuptakeandnitricoxidereleaseinvascularendothelialcells:R.G.Bogle,etal.;BBRC180,926(1991)
- Biosynthesisofendothelium-derivednitricoxidebybradykininasendogenousprecursor:A.R.Volpe,etal.;Immunopharmacology33,287(1996)
- BradykininstimulatesNF-kappaBactivationandinterleukin1betageneexpressioninculturedhumanfibroblasts:Z.K.Pan,etal.;J.Clin.Invest.98,2042(1996)
- Bradykininandnitricoxideininfectiousdiseaseandcancer:H.Maeda,etal.;Immunopharmacol.33,222(1996)
- Bradykininreceptorsandtheirantagonists:D.Regoli,etal.;Eur.J.Pharmacol.348,1(1998)
- Reciprocalphosphorylationandregulationofendothelialnitric-oxidesynthaseinresponsetobradykininstimulation:M.B.Harris,etal.;J.Biol.Chem.276,16587(2001)
- Internationalunionofpharmacology.XLV.Classificationofthekininreceptorfamily:frommolecularmechanismstopathophysiologicalconsequences:L.M.Leeb-Lundberg,etal.;Pharmacol.Rev.57,27(2005)
- Formationofbradykinin:amajorcontributortotheinnateinflammatoryresponse:K.Joseph&A.P.Kaplan;Adv.Immunol.86,159(2005)
- Peptideandnon-peptidebradykininreceptorantagonists:roleinallergicairwaydisease:W.M.Abraham,etal.;Eur.J.Pharmacol.533,215(2006)
- BradykininmediatesphosphorylationofeNOSinodontoblasts:Y.Korkmaz,etal.;J.Dent.Res.85,536(2006)
- Multifunctionaleffectsofbradykininonglialcellsinrelationtopotentialanti-inflammatoryeffects:M.Noda,etal.;NeuRochem.Int.51,185(2007)
- Pathogenicmechanismsofbradykininmediateddiseases:Dysregulationofaninnateinflammatorypathway:A.P.Kaplan&K.Joseph;Adv.Immunol.121,41(2014)
品牌介绍
Adipogen公司由三个子公司组成，分别是Adipogen,Inc.(韩国),AdipogenSA(瑞士)和 AdipogenCorporation(美国圣地亚哥)。总部设在美国，运营总部在瑞士利斯塔尔。Adipogen公司专门从事生命科学研究试剂的开发，如癌症、免疫、炎症、代谢疾病（糖尿病、肥胖）、干细胞和神经退行性疾病等领域。其重点关注开发创新优质的ELISA试剂盒。另外，也可提供抗体和蛋白产品，Adipogen拥有自己的化学实验室，致力于开发创新型小分子化合物。
联络我们
