Adipogen/bpV(phen)/AG-CR1-0042-M025/25 mg
商品编号：
AG-CR1-0042-M025
品牌：
Adipogen Inc
市场价：
¥4200.00
美元价：
2520.00
产品分类：
其他试剂
公司分类：
Other_reagents
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
| Product Details | |
|---|---|
| Synonyms | Potassium bisperoxo (1,10-phenanthroline) oxovanadate (V) |
| Product Type | Chemical |
| Properties | |
| Formula | K[VO(O2)2C12H8N2] . 3H2O |
| MW | 350.2 . 54.0 |
| CAS | 171202-16-7 |
| Purity Chemicals | ≥99% (51V-NMR) |
| Appearance | Yellow to orange crystalline solid. |
| Solubility | Soluble in DMSO or water. |
| Identity | Determined by 51V-NMR (D2O). |
| InChi Key | PKEQYULPAHCPOP-UHFFFAOYSA-N |
| Shipping and Handling | |
| Shipping | AMBIENT |
| Short Term Storage | +4°C |
| Long Term Storage | -20°C |
| Handling Advice | Protect from light. |
| Use/Stability | Stable for at least 2 years after receipt when stored at -20°C. |
| Documents | |
| MSDS |
 Download PDF |
| Product Specification Sheet | |
| Datasheet |
Download PDF |
- Potent protein phosphotyrosine phosphatase inhibitor [1, 2, 5].
- Insulin receptor kinase (IRK) inducer [2].
- Insulin mimetic in vitro and in vivo [3, 4].
- Apoptosis inducer [6].
- ERK inducer [7].
- Mitogen-activated protein kinase phosphatase-1 (MKP-1) inducer [7].
- Angiogenesis inhibitor [8].
- PTEN inhibitor [9].
Product References
- Peroxovanadium compounds. A new class of potent phosphotyrosine phosphatase inhibitors which are insulin mimetics: B.I. Posner, et al.; J. Biol. Chem. 269, 4596 (1994)
- Early signaling events triggered by peroxovanadium [bpV(phen)] are insulin receptor kinase (IRK)-dependent: specificity of inhibition of IRK-associated protein tyrosine phosphatase(s) by bpV(phen): C.J. Band, et al.; Mol. Endocrinol. 11, 1899 (1997)
- Hypoglycemic effects of peroxovanadium compounds in Sprague-Dawley and diabetic BB rats: J.F. Yale, et al.; Diabetes 44, 1274 (1995)
- In vivo insulin mimetic effects of pV compounds: role for tissue targeting in determining potency: A.P. Bevan, et al.; Am. J. Physiol. 268, E60 (1995)
- A role for tyrosine phosphorylation in both activation and inhibition of the insulin receptor tyrosine kinase in vivo: P.G. Drake, et al.; Endocrinology 137, 4960 (1996)
- BpV (phen) induces apoptosis of RINm5F cells by modulation of MAPKs and MKP-1: L. Rumora, et al.; BBRC 300, 877 (2003)
- Positive regulation of ERK activation and MKP-1 expression by peroxovanadium complex bpV (phen): L. Rumora, et al.; Cell Biol. Toxicol. 20, 293 (2004)
- Peroxovanadium compounds as inhibitors of angiogenesis: C. J. Doillon, et al.; Angiogenesis 3, 361 (1999)
- Bisperoxovanadium compounds are potent PTEN inhibitors: A.C. Schmid, et al.; FEBS Lett. 566, 35 (2004)
品牌介绍
Adipogen公司由三个子公司组成，分别是Adipogen,Inc.(韩国),AdipogenSA(瑞士)和 AdipogenCorporation(美国圣地亚哥)。总部设在美国，运营总部在瑞士利斯塔尔。Adipogen公司专门从事生命科学研究试剂的开发，如癌症、免疫、炎症、代谢疾病（糖尿病、肥胖）、干细胞和神经退行性疾病等领域。其重点关注开发创新优质的ELISA试剂盒。另外，也可提供抗体和蛋白产品，Adipogen拥有自己的化学实验室，致力于开发创新型小分子化合物。
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