Adipogen/Bilobalide/AG-CN2-0026-M010/10 mg
商品编号：
AG-CN2-0026-M010
品牌：
Adipogen Inc
市场价：
¥1300.00
美元价：
780.00
产品分类：
其他试剂
公司分类：
Other_reagents
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
| ProductDetails | |
|---|---|
| ProductType | Chemical |
| Properties | |
| Formula | C15H18O8 |
| MW | 326.3 |
| MerckIndex | 14:1220 |
| CAS | 33570-04-6 |
| Source/HostChemicals | IsolatedfromGinkobiloba. |
| PurityChemicals | ≥95%(1H-NMR) |
| Appearance | Whitesolid. |
| Solubility | SolubleinethanolorDMSO. |
| Identity | Determinedby1H-NMR. |
| InChiKey | MOLPUWBMSBJXER-ISSLQHLCSA-N |
| ShippingandHandling | |
| Shipping | AMBIENT |
| ShortTermStorage | +4°C |
| LongTermStorage | -20°C |
| Use/StABIlity | Stableforatleast2yearsafterreceiptwhenstoredat-20°C. Workingaliquotsarestableforupto3monthswhenstoredat-20°C. |
| Documents | |
| MSDS |  DownloadPDF |
| ProductSpecificationSheet | |
| Datasheet | DownloadPDF |
- Neuroprotective[2,3,4,5,7].
- Mitochondrialgeneexpressionregulator[3].
- ROSscavenger[4].
- CompetitiveGABA(A)receptorantagoNIST[6].
- Apoptosisinhibitor[4,7,10,11].
- CREBphosphorylationenhancer.Stimulatesneurogenesisandsynaptogenesis[8].
- HepaticcytochromeP450inducer[9].
- Activatesthephosphatidylinositol3-kinase(PI3K)dependentpathway[10,11].
- Potentanti-inflammatoryandantihyperalgesicagent[12].
ProductReferences
- BilobalidA,einneuesSesquiterpenmittert.-Butyl-GruppeausdenBlätternvonGinkgobilobaL.:K.Weinges&W.Bähr;LiebigsAnn.Chem.724,214(1969)
- Protectionofhypoxia-inducedATPdecreaseinendothelialcellsbyginkgobilobaextractandbilobalide:D.Janssens,etal.;Biochem.Pharmacol.50,991(1995)
- Protectionofmitochondrialrespirationactivitybybilobalide:D.Janssens,etal.;Biochem.Pharmacol.58,109(1999)
- Reactiveoxygenspecies-inducedapoptosisinPC12cellsandprotectiveeffectofbilobalide:L.J.Zhou&X.Z. Zhu;J.Pharmacol.Exp.Ther.293,982(2000)
- Bilobalideandneuroprotection:F.V.Defeudis;Pharmacol.Res.46,565(2002)(Review)
- Bilobalide,asesquiterpenetrilactonefromGinkgobiloba,isanantagonistatrecombinantalpha1beta2gamma2LGABA(A)receptors:S.H.Huang,etal.;Eur.J.Pharmacol.464,1(2003)
- Neuroprotectiveeffectsofbilobalide,acomponentofGinkgobilobaextract(EGb761)inglobalbrainischemiaandinexcitotoxicity-inducedneuronaldeath:K.Chandrasekaran,etal.;Pharmacopsychiatry36Suppl1,S89(2003)
- Stimulationofneurogenesisandsynaptogenesisbybilobalideandquercetinviacommonfinalpathwayinhippocampalneurons:F.Tchantchou,etal.;J.AlzheimersDis.18,787(2009)
- Time-dependentinductionofhepaticcytochromeP450enzymeactivityandmRNAexpressionbybilobalideinrats:Y.Taki,etal.;J.Pharmacol.Sci.109,459(2009)
- BilobalidepreventsapoptosisthroughactivationofthePI3K/AktpathwayinSH-SY5Ycells:C.Shi,etal.;Apoptosis15,715(2010)
- Bilobalideregulatessolubleamyloidprecursorproteinreleaseviaphosphatidylinositol3kinase-dependentpathway:C.Shi,etal.;NeuRochem.Int.59,59(2011)
- Bilobalide,auniqueconstituentofGinkgobiloba,inhibitsinflammatorypaininrats:M.Goldie&S.Dolan;Behav.Pharmacol.24,298(2013)
品牌介绍
Adipogen公司由三个子公司组成，分别是Adipogen,Inc.(韩国),AdipogenSA(瑞士)和 AdipogenCorporation(美国圣地亚哥)。总部设在美国，运营总部在瑞士利斯塔尔。Adipogen公司专门从事生命科学研究试剂的开发，如癌症、免疫、炎症、代谢疾病（糖尿病、肥胖）、干细胞和神经退行性疾病等领域。其重点关注开发创新优质的ELISA试剂盒。另外，也可提供抗体和蛋白产品，Adipogen拥有自己的化学实验室，致力于开发创新型小分子化合物。
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