| ProductDetails | |
|---|---|
| Synonyms | NaturalYellow18;Berberiniumchloride;BBR;Umbellatine;Majarine;Thalsine |
| ProductType | Chemical |
| Properties | |
| Formula | C20H17NO4.HCl |
| MW | 335.3.36.5 |
| CAS | 633-65-8 |
| Source/HostChemicals | Synthetic |
| PurityChemicals | ≥98%(TLC) |
| Appearance | Yellowtoorangepowder. |
| Solubility | SolubleinDMSOormethanol.Slightlysolubleinethanolorwater. |
| Identity | DeterminedbyNMR. |
| Declaration | ManufacturedbyChemodex. |
| OtherProductData | ClickhereforOriginalManufacturerProductDatasheet Ourproductdescriptionmaydifferslightlyfromtheoriginalmanufacturersproductdatasheet. |
| InChiKey | VKJGBAJNNALVAV-UHFFFAOYSA-M |
| ShippingandHandling | |
| Shipping | AMBIENT |
| ShortTermStorage | +4°C |
| LongTermStorage | +4°C |
| HandlingAdvice | Keepcoolanddry. Protectfromlightandmoisture. |
| Use/StABIlity | Stableforatleast2yearsafterreceiptwhenstoredat+4°C. |
| Documents | |
| MSDS | No |
| ProductSpecificationSheet | |
| Datasheet |  DownloadPDF |
Naturalfluorescentdye,usedinhistologyforstainingheparininmastcells.Anisoquinolinealkaloid,whichshowsantibacterial,antifungal,anti-inflammatory,anti-oxidant,antidiabetic,antiviralandanticanceractivity.Itinhibitscellgrowthandinducesapoptosisinavarietyofcancercelllines.Broadspectrumenzymeinhibitor,affectsN-acetyltransferase,cyclooxygenase-2,andtopoisomeraseactivitiesandgene/proteinexpression.IncreasesADIponectinexpression,upregulatesLDLRandinsulinreceptor.Anti-hyperglycemic,byinhibitionofaldosereductase,inducingglycolysis,preventinginsulinresistancethroughincreasinginsulinreceptorexpressionandactinglikeincretins.ActivatesAMPKandERK.
(1)P.J.Kaboli,etal.;Eur.J.Pharmacol.740,584(2014)|(2)L.M.Ortiz,etal.;Molecules19,12349(2014)|(3)W.J.Ni,etal.;Eur.J.Pharmacol.760,103(2015)|(4)C.J.Yu,etal.;J.AlzheimersDis.22,257(2010)
