Adipogen/Becatecarin/BVT-0258-M001/1 mg
商品编号：
BVT-0258-M001
品牌：
Adipogen Inc
市场价：
¥9800.00
美元价：
5880.00
产品分类：
其他试剂
公司分类：
Other_reagents
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
| ProductDetails | |
|---|---|
| Synonyms | 6-N-[2-(Diethylamino)ethyl]rebeccamycin;NSC655649;BMY-27557-14;BMS-181176;XL119 |
| ProductType | Chemical |
| Properties | |
| Formula | C33H34Cl2N4O7 |
| MW | 669.6 |
| CAS | 119673-08-4 |
| Source/HostChemicals | Semisynthetic. |
| PurityChemicals | ≥98%(HPLC) |
| Appearance | Yellowsolid. |
| Solubility | SolubleinDMSOorwater(pHdependent). |
| Identity | Determinedby1H-NMR. |
| Declaration | ManufacturedbyBioViotica. |
| InChiKey | JSKFWUPVIZYJMR-UDOAKELVSA-N |
| ShippingandHandling | |
| Shipping | AMBIENT |
| ShortTermStorage | +4°C |
| LongTermStorage | -20°C |
| Use/StABIlity | Stableforatleast1yearafterreceiptwhenstoredat-20°C. Afterreconstitutionprotectfromlightat-20°C. |
| Documents | |
| MSDS |  DownloadPDF |
| ProductSpecificationSheet | |
| Datasheet | DownloadPDF |
- Antibiotic.
- Semisyntheticwater-solublederivativeofrebeccamycin(Prod.No.BVT-0139).
- Antitumorcompound.
- TopoisomeraseII(TopoII)inhibitor.
- DNAintercalatingagent.
ProductReferences
- Watersolublederivativesofrebeccamycin:T.Kaneko,etal.;J.Antibiot.43,125(1990)
- Discoveryofantitumorindolocarbazoles:rebeccamycin,NSC655649,andfluoroindolocarbazoles:B.H.Long,etal.;Curr.Med.Chem.AnticancerAgents2,255(2002)
- Becatecarin(HelsinnHealthcare):G.W.Rewcastle;IDrugs8,838(2005)(Review)
- PhaseIandpharmacokineticstudyofsequencesoftherebeccamycinanalogueNSC655649andcisplatininpatientswithadvancedsolidtumors:A.D.Ricart,etal.;Clin.CancerRes.11,8728(2005)
- AphaseIItrialofrebeccamycinanalogue(NSC#655649)inchildrenwithsolidtumors:achildren`soncologygroupstudy:A.-M.Langevin,etal.;Pediatr.BloodCancer50,577(2008)
- Becatecarin(rebeccamycinanalog,NSC655649)isatransportsubstrateandinducesexpressionoftheATP-bindingcassettetransporter,ABCG2,inlungcarcinomacells:R.W.Robey,etal.;CancerChemother.Pharmacol.64,575(2009)
品牌介绍
Adipogen公司由三个子公司组成，分别是Adipogen,Inc.(韩国),AdipogenSA(瑞士)和 AdipogenCorporation(美国圣地亚哥)。总部设在美国，运营总部在瑞士利斯塔尔。Adipogen公司专门从事生命科学研究试剂的开发，如癌症、免疫、炎症、代谢疾病（糖尿病、肥胖）、干细胞和神经退行性疾病等领域。其重点关注开发创新优质的ELISA试剂盒。另外，也可提供抗体和蛋白产品，Adipogen拥有自己的化学实验室，致力于开发创新型小分子化合物。
联络我们
