
Adipogen/Becatecarin/BVT-0258-C250/250 µg
商品编号:
BVT-0258-C250
品牌:
Adipogen Inc
市场价:
¥3400.00
美元价:
2040.00
产品分类:
其他试剂
公司分类:
Other_reagents
联系Q Q:
3392242852
电话号码:
4000-520-616
电子邮箱:
info@ebiomall.com
商品介绍
ProductDetails | |
---|---|
Synonyms | 6-N-[2-(Diethylamino)ethyl]rebeccamycin;NSC655649;BMY-27557-14;BMS-181176;XL119 |
ProductType | Chemical |
Properties | |
Formula | C33H34Cl2N4O7 |
MW | 669.6 |
CAS | 119673-08-4 |
Source/HostChemicals | Semisynthetic. |
PurityChemicals | ≥98%(HPLC) |
Appearance | Yellowsolid. |
Solubility | SolubleinDMSOorwater(pHdependent). |
Identity | Determinedby1H-NMR. |
Declaration | ManufacturedbyBioViotica. |
InChiKey | JSKFWUPVIZYJMR-UDOAKELVSA-N |
ShippingandHandling | |
Shipping | AMBIENT |
ShortTermStorage | +4°C |
LongTermStorage | -20°C |
Use/StABIlity | Stableforatleast1yearafterreceiptwhenstoredat-20°C. Afterreconstitutionprotectfromlightat-20°C. |
Documents | |
MSDS | ![]() |
ProductSpecificationSheet | |
Datasheet | ![]() |
- Antibiotic.
- Semisyntheticwater-solublederivativeofrebeccamycin(Prod.No.BVT-0139).
- Antitumorcompound.
- TopoisomeraseII(TopoII)inhibitor.
- DNAintercalatingagent.
ProductReferences
- Watersolublederivativesofrebeccamycin:T.Kaneko,etal.;J.Antibiot.43,125(1990)
- Discoveryofantitumorindolocarbazoles:rebeccamycin,NSC655649,andfluoroindolocarbazoles:B.H.Long,etal.;Curr.Med.Chem.AnticancerAgents2,255(2002)
- Becatecarin(HelsinnHealthcare):G.W.Rewcastle;IDrugs8,838(2005)(Review)
- PhaseIandpharmacokineticstudyofsequencesoftherebeccamycinanalogueNSC655649andcisplatininpatientswithadvancedsolidtumors:A.D.Ricart,etal.;Clin.CancerRes.11,8728(2005)
- AphaseIItrialofrebeccamycinanalogue(NSC#655649)inchildrenwithsolidtumors:achildren`soncologygroupstudy:A.-M.Langevin,etal.;Pediatr.BloodCancer50,577(2008)
- Becatecarin(rebeccamycinanalog,NSC655649)isatransportsubstrateandinducesexpressionoftheATP-bindingcassettetransporter,ABCG2,inlungcarcinomacells:R.W.Robey,etal.;CancerChemother.Pharmacol.64,575(2009)
品牌介绍
Adipogen公司由三个子公司组成,分别是Adipogen,Inc.(韩国),AdipogenSA(瑞士)和 AdipogenCorporation(美国圣地亚哥)。总部设在美国,运营总部在瑞士利斯塔尔。Adipogen公司专门从事生命科学研究试剂的开发,如癌症、免疫、炎症、代谢疾病(糖尿病、肥胖)、干细胞和神经退行性疾病等领域。其重点关注开发创新优质的ELISA试剂盒。另外,也可提供抗体和蛋白产品,Adipogen拥有自己的化学实验室,致力于开发创新型小分子化合物。
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