Adipogen/Bakuchiol/AG-CN2-0495-M001/1 mg
商品编号：
AG-CN2-0495-M001
品牌：
Adipogen Inc
市场价：
¥500.00
美元价：
300.00
产品分类：
其他试剂
公司分类：
Other_reagents
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
| ProductDetails | |
|---|---|
| Synonyms | S-Bakuchiol;(+)-Bakuchiol;Bakutrol;Drupanol;SytenolA;UP256;(S,E)-4-(3,7-Dimethyl-3-vinylocta-1,6-dien-1-yl)phenol |
| ProductType | Chemical |
| Properties | |
| Formula | C18H24O |
| MW | 256.4 |
| CAS | 10309-37-2 |
| Source/HostChemicals | IsolatedfromPsoraleacorylifolia. |
| PurityChemicals | ≥98%(HPLC) |
| Appearance | Yellowtobrownishoil. |
| Solubility | SolubleinDMSO,ethanolormethanol. |
| Identity | Determinedby1H-NMRandMS. |
| InChiKey | LFYJSSARVMHQJB-QIXNEVBVSA-N |
| ShippingandHandling | |
| Shipping | AMBIENT |
| ShortTermStorage | +4°C |
| LongTermStorage | -20°C |
| HandlingAdvice | Protectfromlight. |
| Use/StABIlity | Stableforatleast2yearsafterreceiptwhenstoredat-20°C. |
| Documents | |
| MSDS |  DownloadPDF |
| ProductSpecificationSheet | |
| Datasheet | DownloadPDF |
- Antibiotic.
- Antimicrobial,anti-inflammatory,anticancerandimmunosuppressivecompound.Showntohavehepatoprotectiveandhypoglycemicactivity.
- Apoptosisinducerincancercells.Sensitizescancercells.Inducescellcyclearrest.
- Antiviralagent.InhibitedinfluenzaAviralinfectionandgrowththroughactivationofNrf2.
- Inhibitorofproteintyrosinephosphatase1B(PTB1B).
- Antioxidant.Inhibitorofmitochondriallipidperoxidation.
- InhibitorofinducIBLenitricoxidesynthase(iNOS;NOSII)expressionviainactivationofNF-κB.
- DNApolymeraseandUDP-glucuronosyltransferaseinhibitor.
- Anti-agingcompoundwithretinol-likeeffectsongeneexpressionandpropertiesoftheskin.
- PhospholipaseA,cyclooxygenase-1(COX-1)andHIF-1inhibitor.
ProductReferences
- DNApolymeraseandtopoisomeraseIIinhibitorsfromPsoraleacorylifolia:N.J.Sun,etal.;J.Nat.Prod.61,362(1998)
- IsolationandantihyperglycemicactivityofbakuchiolfromOtholobiumpubescens(Fabaceae),aPeruvianmedicinalplantusedforthetreatmentofdiabetes:J.M.Krenisky,etal.;Biol.Pharm.Bull.22,1137(1999)
- InhibitionofmitochondriallipidperoxidationbyBakuchiol,ameroterpenefromPsoraleacorylifolia:H.Haraguchi,etal.;PlantaMed.66,569(2000)
- Invitroantimicrobialactivitiesofbakuchiolagainstoralmicroorganisms:H.Katsura,etal.;Antimicrob.AgentsChemother.45,3009(2001)
- BakuchiolfromPsoraleacorylifoliainhibitstheexpressionofinduciblenitricoxidesynthasegeneviatheinactivationofnucleartranscriptionfactor-kappaBinRAW264.7macrophages:H.O.Pae,etal.;Int.Immunopharmacol.1,1849(2001)
- Bakuchiol:ahepatoprotectivecompoundofPsoraleacorylifoliaontacrine-inducedcytotoxicityinHepG2cells:H.Cho,etal.;PlantaMed.67,750(2001)
- AntioxidativecomponentsofPsoraleacorylifolia(Leguminosae):H.Haraguchi,etal.;Phytother.Res.16,539(2002)
- PreparationandinvitroevaluationofrADIoiodinatedbakuchiolasanantitumoragent:K.Bapat,etal.;Appl.Radiat.Isot.62,389(2005)
- Invitroproteintyrosinephosphatase1BinhibitoryphenolsfromtheseedsofPsoraleacorylifolia:Y.C.Kim,etal.;PlantaMed.71,87(2005)
- Bakuchiol-inducedcaspase-3-dependentapoptosisoccursthroughc-JunNH2-terminalkinase-mediatedmitochondrialtranslocationofBaxinratlivermyofibroblasts:E.J.Park,etal.;Eur.J.Pharmacol.559,115(2007)
- BisbakuchiolsAandB,noveldimericmeroterpenoidsfromPsoraleacorylifolia:C.-Z.Wu,etal.;Tetrahedr.Lett.48,8861(2007)
- Bakuchiol,anantibacterialcomponentofPsoralidiumtenuiflorum:P.J.Hsu,etal.;Nat.Prod.Res.23,781(2009)
- Isolationandanti-inflammatoryactivityofBakuchiolfromUlmusdavidianavar.japonica:S.Y.Choi,etal.;J.Med.Food13,1019(2010)
- Invitroevidenceforbakuchiol"sinfluencetowardsdrugmetabolismthroughinhibitionofUDP-glucuronosyltransferase(UGT)2B7:Y.Xu,etal.;Afr.HealthSci.14,564(2014)
- Bakuchiol:Aretinol-likefunctionalcompoundrevealedbygeneexpressionprofilingandclinicallyproventohaveanti-agingeffects:R.K.Chaudhuri&K.Bojanowski;Int.J.Cosmet.Sci.36,221(2014)
- Bakuchiolisaphenolicisoprenoidwithnovelenantiomer-selectiveanti-influenzaavirusactivityinvolvingNrf2activation:M.Shoji,etal.;J.Biol.Chem.290,28001(2015)
- BakuchiolsensitizescancercellstoTRAILthroughROS-andJNK-mediatedupregulationofdeathreceptorsanddownregulationofsurvivalproteins:M.H.Park,etal.;BBRC473,586(2016)
- PhytoestrogenBakuchiolExhibitsInVitroandInVivoAnti-breastCancerEffectsbyInducingSPhaseArrestandApoptosis:L.Li,etal.;Front.Pharmacol.7,128(2016)
- IdentificationofUDP-glucuronosyltransferases1A1,1A3and2B15asthemaincontributorstoglucuronidationofbakuchiol,anaturalBIOLOGicallyactivecompound:F.Li,etal.;Xenobiotica(Epubaheadofprint)(2016)
- BakuchiolsuppressesproliferationofskincancercellsbydirectlytargetingHck,Blk,andp38MAPkinase:J.E.Kim,etal.;Oncotarget7,14616(2016)
品牌介绍
Adipogen公司由三个子公司组成，分别是Adipogen,Inc.(韩国),AdipogenSA(瑞士)和 AdipogenCorporation(美国圣地亚哥)。总部设在美国，运营总部在瑞士利斯塔尔。Adipogen公司专门从事生命科学研究试剂的开发，如癌症、免疫、炎症、代谢疾病（糖尿病、肥胖）、干细胞和神经退行性疾病等领域。其重点关注开发创新优质的ELISA试剂盒。另外，也可提供抗体和蛋白产品，Adipogen拥有自己的化学实验室，致力于开发创新型小分子化合物。
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