Adipogen/Bafilomycin C<sub>1</sub>/BVT-0068-M001/1 mg
商品编号：
BVT-0068-M001
品牌：
Adipogen Inc
市场价：
¥2800.00
美元价：
1680.00
产品分类：
其他试剂
公司分类：
Other_reagents
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
| ProductDetails | |
|---|---|
| Synonyms | L-681,110A1;2-Demethyl-2-methoxy-24-methyl-hygrolidin |
| ProductType | Chemical |
| Properties | |
| Formula | C39H60O12 |
| MW | 720.9 |
| CAS | 88979-61-7 |
| Source/HostChemicals | IsolatedfromStreptomycessp.Gö14F. |
| PurityChemicals | ≥98%(HPLC) |
| Appearance | Yellowpowder. |
| Solubility | Solublein100%ethanol,methanol,DMSOordimethylformamide. |
| Identity | Determinedby1H-NMR. |
| Declaration | ManufacturedbyBioViotica. |
| OtherProductData | Mayundergotransformationtomethylketalonlongtermstorageinmethanol.Werecommendtheuseoffreshsolutions. |
| InChiKey | WUDBXVQNMOTFEE-WSNZTHDZSA-N |
| ShippingandHandling | |
| Shipping | AMBIENT |
| ShortTermStorage | +4°C |
| LongTermStorage | -20°C |
| HandlingAdvice | Protectfromlightwheninsolution. |
| Use/StABIlity | Stableforatleast1yearafterreceiptwhenstoredat-20°C. Afterreconstitutionprotectfromlightat-20°C. |
| Documents | |
| MSDS |  DownloadPDF |
| ProductSpecificationSheet | |
| Datasheet | DownloadPDF |
- Antibiotic.
- Specificvacuolar-typeH+-ATPaseinhibitor.
- InhibitorofautophagicdegradationbyrisinglysosomalpHandthusinactivatingthelysosomalacidhydrolases.
- Antibacterial,antifungal,insecticidalandanthelmintic.
- Potentialanti-osteoporoticagentintreatingbonelyticdiseases.
- Neuroprotectioninducer.
ProductReferences
- Metabolicproductsofmicroorganisms.224.Bafilomycins,anewgroupofmacrolideantibiotics.Production,isolation,chemicalstructureandBIOLOGicalactivity:G.Werner,etal.;J.Antibiot.(Tokyo)37,110(1984)
- PurificationofvacuolarATPasewithbafilomycinC1affinitychromatography:T.J.Rautiala,etal.;BBRC194,50(1993)
- Bafilolides,potentinhibitorsofthemotilityanddevelopmentofthefree-livingstagesofparasiticnematodes:E.Lacey,etal.;Int.J.Parasitol.25,349(1995)
- Autophagy,bafilomycinandcelldeath:the"a-B-cs"ofplecomacrolide-inducedneuroprotection:J.J.Shacka,etal.;Autophagy2,228(2006)(Review)
- StructureandfunctionofV-ATPasesinosteoclasts:potentialtherapeutictargetsforthetreatmentofosteolysis:J.Xu,etal.;Histol.Histopathol.222,443(2007)
- Low-doseBafilomycinattenuatesneuronalcelldeathassociatedwithautophagy-lysosomepathwaydysfunction:V.Pivtoraiko,et.al.;J.NeuRochem.114,1193(2010)
- Alterationsinosteoclastfunctionandphenotypeinducedbydifferentinhibitorsofboneresorption-implicationsforosteoclastquality:A.Neutzsky-Wulff,et.al.;BMCMusculoskel.Disord.11,1471(2010)
品牌介绍
Adipogen公司由三个子公司组成，分别是Adipogen,Inc.(韩国),AdipogenSA(瑞士)和 AdipogenCorporation(美国圣地亚哥)。总部设在美国，运营总部在瑞士利斯塔尔。Adipogen公司专门从事生命科学研究试剂的开发，如癌症、免疫、炎症、代谢疾病（糖尿病、肥胖）、干细胞和神经退行性疾病等领域。其重点关注开发创新优质的ELISA试剂盒。另外，也可提供抗体和蛋白产品，Adipogen拥有自己的化学实验室，致力于开发创新型小分子化合物。
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