Adipogen/Bafilomycin B<sub>1</sub>/BVT-0004-C100/100 µg
商品编号：
BVT-0004-C100
品牌：
Adipogen Inc
市场价：
¥1000.00
美元价：
600.00
产品分类：
其他试剂
公司分类：
Other_reagents
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
| ProductDetails | |
|---|---|
| Synonyms | Setamycin;BRN4640118 |
| ProductType | Chemical |
| Properties | |
| Formula | C44H65NO13 |
| MW | 815.9 |
| CAS | 88899-56-3 |
| RTECS | LX8920000 |
| Source/HostChemicals | IsolatedfromStreptomyceshygroscopicus. |
| PurityChemicals | ≥97%(HPLC) |
| Appearance | Yellowsolid. |
| Solubility | SolubleinDMSOoracetone.Insolubleinwater.Unstableinmethanol. |
| Identity | Determinedby1H-NMR. |
| Declaration | ManufacturedbyBioViotica. |
| InChiKey | KFUFLYSBMNNJTF-APLCIVFZSA-N |
| ShippingandHandling | |
| Shipping | AMBIENT |
| ShortTermStorage | +4°C |
| LongTermStorage | -20°C |
| HandlingAdvice | Protectfromlightwheninsolution. |
| Use/StABIlity | Stableforatleast1yearafterreceiptwhenstoredat-20°C. Afterreconstitutionprotectfromlightat-20°C. |
| Documents | |
| MSDS |  DownloadPDF |
| ProductSpecificationSheet | |
| Datasheet | DownloadPDF |
- Macrolideantibiotic.
- Specificvacuolar-typeH+-ATPaseinhibitor.
- InhibitorofautophagicdegradationbyrisinglysosomalpHandthusinactivatingthelysosomalacidhydrolases.
- Antitrypanosomalandantileishmanialcompound.
- Phytotoxic.
- InfluencesthecellwallbiosynthesisofAsp.niger.
ProductReferences
- Metabolicproductsofmicroorganisms.224.Bafilomycins,anewgroupofmacrolideantibiotics.Production,isolation,chemicalstructureandBIOLOGicalactivity:G.Werner,etal.;J.Antibiot.(Tokyo)37,110(1984)
- InhibitoryeffectofmodifiedbafilomycinsandconcanamycinsonP-andV-typeadenosinetriphosphatases:S.Drose,etal.;Biochemistry32,3902(1993)
- BafilomycinsandconcanamycinsasinhibitorsofV-ATPasesandP-ATPases:S.DroseandK.Altendorf;J.Exp.Biol.200,1(1997)
- BiosyntheticinvestigationsoftheV-typeATPaseinhibitorsbafilomycinA1,B1andconcanamycinA:T.SchuhmannandS.Grond;J.Antibiot.(Tokyo)57,655(2004)
- Autophagy,bafilomycinandcelldeath:the"a-B-cs"ofplecomacrolide-inducedneuroprotection:J.J.Shacka,etal.;Autophagy2,228(2006)
- BafilomycinsproducedinculturebyStreptomycesspp.isolatedfrommarinehabitatsarepotentinhibitorsofautophagy:G.Carr,etal.;JournalofNat.Prod.73,422(2010)
- Low-dosebafilomycinattenuatesneuronalcelldeathassociatedwithautophagy-lysosomepathwaydysfunction:V.N.Pivtoraiko;J.NeuRochem.114,1193(2010)
- VacuolarH(+)-ATPaseplaysakeyroleincellwallbiosynthesisofAspergillusniger:D.Schachtschabel,etal.; Fungalgenet.Biol.49,284(2012)
- CharacterizationofthebafilomycinbiosyntheticgeneclusterfromStreptomyceslohii:W.Zhang,etal.;ChemBioChem14,301(2013)
- IsolationandcharacterizationofphytotoxiccompoundsproducedbyStreptomycessp.AMC23fromredmangrove(rhizophoramangle):E.Crevelin,etal.;Appl.Biochem.Biotechnol.171,1602(2013)
- High-throughputscreeningplatformfornaturalproduct-baseddrugdiscoveryagainst3neglectedtropicaldiseases:humanAfricantrypanosomiasis,leishmaniasis,andchagasdisease:F.Annang,etal.;J.Biomol.Screen.20,82(2015)
品牌介绍
Adipogen公司由三个子公司组成，分别是Adipogen,Inc.(韩国),AdipogenSA(瑞士)和 AdipogenCorporation(美国圣地亚哥)。总部设在美国，运营总部在瑞士利斯塔尔。Adipogen公司专门从事生命科学研究试剂的开发，如癌症、免疫、炎症、代谢疾病（糖尿病、肥胖）、干细胞和神经退行性疾病等领域。其重点关注开发创新优质的ELISA试剂盒。另外，也可提供抗体和蛋白产品，Adipogen拥有自己的化学实验室，致力于开发创新型小分子化合物。
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