Adipogen/Avarol/AG-CN2-0044-M001/1 mg
商品编号：
AG-CN2-0044-M001
品牌：
Adipogen Inc
市场价：
¥2500.00
美元价：
1500.00
产品分类：
其他试剂
公司分类：
Other_reagents
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
| ProductDetails | |
|---|---|
| Synonyms | NSC306951 |
| ProductType | Chemical |
| Properties | |
| Formula | C21H30O2 |
| MW | 314.5 |
| CAS | 55303-98-5 |
| Source/HostChemicals | IsolatedfromspongeDysideaavara. |
| PurityChemicals | ≥97%(HPLC) |
| Appearance | Off-whitesolid. |
| Solubility | SolubleinethanolorDMSO. |
| Identity | Determinedby1H-NMR. |
| InChiKey | JSPUCPNQXKTYRO-LWILDLIXSA-N |
| ShippingandHandling | |
| Shipping | AMBIENT |
| ShortTermStorage | +4°C |
| LongTermStorage | -20°C |
| HandlingAdvice | Keepcoolanddry. Protectfromlight. |
| Use/StABIlity | Stableforatleast2yearsafterreceiptwhenstoredat-20°C. Storesolutionsat-20°Cinthedark. |
| Documents | |
| MSDS |  DownloadPDF |
| ProductSpecificationSheet | |
| Datasheet | DownloadPDF |
- AntibacterialagainstselectedGram-positivestrains,antifungal[1,6].
- Anticancercompound[2].
- Antileukemic[4,5,8,9].
- Antimitoticagent[3].
- Antiviralcompound [7,8,14].
- InhibitsHIVactivity[7,8,14].
- Anti-inflammatory[10,12].
- SynovialphospholipaseA2,cyclooxygenaseandlipoxygenaseinhibitor[10,12].
- Modulatorofsuperoxidedismutaseandglutathioneperoxidase[11].
- Plateletaggregationinhibitor[13].
- Anti-psoriatic[15,17],mediatedbyinhibitionofTNF-αgenerationandNF-κBactivation[18,19].
- Reviews[16,20].
ProductReferences
- Antimicrobialactivityofavarol,asesquiterpenoidhydroquinonefromthemarinesponge,Dysideaavara:L.Cariello,etal.;Comp.Biochem.Physiol.B.71,281(1982)
- Avarol,acytostaticallyactivecompoundfromthemarinespongeDysideaavara:W.E.Müller,etal.;Comp.Biochem.Physiol.C.80,47(1985)
- Inhibitionofmitosisbyavarol,anaturalproductisolatedfromthespongeDysideaavara:W.E.Müller,etal.;BasicAppl.Histochem.29,321(1985)
- Potentantileukemicactivityofthenovelcytostaticagentavaroneanditsanaloguesinvitroandinvivo:W.E.Müller,etal.;CancerRes.45,4822(1985)
- Antimutagenicactivityofthenovelantileukemicagents,avaroneandavarol:B.Kurelec,etal.;Mutat.Res.144,63(1985)
- AntibacterialandantifungalactivityofAvaroneandAvarol:G.Seibert,etal.;Zentralbl.Bakteriol.Mikrobiol.Hyg.A.260,379(1985)
- Inhibitionofreplicationoftheetiologicagentofacquiredimmunedeficiencysyndrome(humanT-lymphotropicretrovirus/lymphadenopathy-associatedvirus)byavarolandavarone:P.S.Sarin,etal.;J.Natl.CancerInst.78,663(1987)
- Influenceoftheantileukemicandanti-humanimmunodeficiencyvirusagentavarolonselectedimmuneresponsesinvitroandinvivo:W.E.Müller,etal.;Biochem.Pharmacol.36,1489(1987)
- Avarol-inducedDNAstrandbreakageinvitroandinFrienderythroleukemiacells:W.E.Müller,etal.;CancerRes.47,6565(1987)
- Inductionofgamma-interferonbyavarolinhumanperipheralbloodlymphocytes:R.Voth,etal.;Jpn.J.CancerRes.79,647(1988)
- Actionoftheantileukemicandanti-HTLV-III(anti-HIV)agentavarolonthelevelsofsuperoxidedismutasesandglutathioneperoxidaseactivitiesinL5178ymouselymphomacells:E.Batke,etal.;CellBiochem.Funct.6,123(1988)
- Avarolandavarone,twonewanti-inflammatoryagentsofmarineorigin:M.L.Ferrandiz,etal.;Eur.J.Pharmacol.253,75(1994)
- Invitroeffectofavaroneandavarol,aquinone/hydroquinonecoupleofmarineorigin,onplateletaggregation:M.A.BELISArio,etal.;Pharmacol.Toxicol.79,300(1996)
- Naturalproductswithanti-HIVactivityfrommarineorganisms:L.A.Tziveleka,etal.;Curr.Top.Med.Chem.3,1512(2003)(Review)
- PotentialantipsoriaticavarolderivativesasantioxidantsandinhibitorsofPGE(2)generationandproliferationintheHaCaTcellline:M.Amigo,etal.;J.Nat.Prod.67,1459(2004)
- ReactivityandBIOLOGicalactivityofthemarinesesquiterpenehydroquinoneavarolandrelatedcompoundsfromspongesoftheorderDictyoceratida:D.SlADIc&M.J.Gasic;Molecules11,1(2006)
- Identificationofavarolderivativesaspotentialantipsoriaticdrugsusinganinvitromodelforkeratinocytegrowthanddifferentiation:M.Amigó,etal.;LifeSci.79,2395(2006)
- Antipsoriaticeffectsofavarol-3"-thiosalicylatearemediatedbyinhibitionofTNF-alphagenerationandNF-kappaBactivationinmouseskin:MAmigó,etal.;Br.J.Pharmacol.152,353(2007)
- AvarolinhibitsTNF-alphagenerationandNF-kappaBactivationinhumancellsandinanimalmodels:M.Amigó,etal.;LifeSci.82,256(2008)
- Cytotoxicterpenequinonesfrommarinesponges:M.Gordaliza;Mar.Drugs8,2849(2010)
品牌介绍
Adipogen公司由三个子公司组成，分别是Adipogen,Inc.(韩国),AdipogenSA(瑞士)和 AdipogenCorporation(美国圣地亚哥)。总部设在美国，运营总部在瑞士利斯塔尔。Adipogen公司专门从事生命科学研究试剂的开发，如癌症、免疫、炎症、代谢疾病（糖尿病、肥胖）、干细胞和神经退行性疾病等领域。其重点关注开发创新优质的ELISA试剂盒。另外，也可提供抗体和蛋白产品，Adipogen拥有自己的化学实验室，致力于开发创新型小分子化合物。
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