Adipogen/Aureothin/BVT-0303-M005/5 mg
商品编号：
BVT-0303-M005
品牌：
Adipogen Inc
市场价：
¥13200.00
美元价：
7920.00
产品分类：
其他试剂
公司分类：
Other_reagents
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
| Product Details | |
|---|---|
| Synonyms | Mycolutein; Distacin; JA 2814K; Antibiotic 74A; BRN 0058476 |
| Product Type | Chemical |
| Properties | |
| Formula | C22H23NO6 |
| MW | 397.4 |
| Merck Index | 10:879 |
| CAS | 2825-00-5 |
| RTECS | UQ0800000 |
| Source/Host Chemicals | Isolated from Streptomyces thioluteus. |
| Purity Chemicals | ≥96% (HPLC) |
| Appearance | Yellow solid. |
| Solubility | Soluble in 100% ethanol, methanol, DMSO, dimethylformamide, dicholormethane or acetone. |
| Identity | Determined by 1H-NMR and UV. |
| Declaration | Manufactured by BioViotica. |
| InChi Key | GQKXCBCSVYJUMI-RCGCBBHSSA-N |
| Shipping and Handling | |
| Shipping | AMBIENT |
| Short Term Storage | +4°C |
| Long Term Storage | -20°C |
| Handling Advice | Protect from light when in solution. |
| Use/Stability |
Stable for at least 1 year after receipt when stored at -20°C. After reconstitution protect from light at -20°C. |
| Documents | |
| MSDS |
 Download PDF |
| Product Specification Sheet | |
| Datasheet |
Download PDF |
- Oxidoreductase inhibitor.
- Antitrypanosomal, antibacterial, antifungal, insecticidal and pesticidal.
- Antitumor compound.
Product References
- The structure of aureothin, a nitro compound obtained from Streptomyces thioluteus: Y. Hirata, et al.; Tetrahedron 14, 252 (1961)
- Identification of mycolutein and pulvomycin as aureothin and labilomycin respectively: J.L. Schwartz, et al.; J. Antibiot. 29, 236 (1976)
- Two binding sites of inhibitors in NADH: ubiquinone oxidoreductase (complex I). Relationship of one site with the ubiquinone-binding site of bacterial glucose:ubiquinone oxidoreductase: T. Friedrich, et al.; Eur. J. Biochem. 219, 691 (1994)
- Absolute configuration of (+)-aureothin: A toxic Metabolite posessing gamma-pyrone unit: Y. Ishibashi, et al.; Bull. Chem. Soc. Jpn. 68, 3643 (1995)
- Gamma-pyrone compounds with selective and potent anti-Helicobacter pylori activity: M. Taniguchi, et al.; J. Antibiot. 53, 844 (2000)
- Dissection of the late steps in aureothin biosynthesis: M. Müller, et al.; ChemBioChem 7, 37 (2006)
- New aureothin derivative, alloaureothin, from Streptomyces sp. MM23: J.Y. Ueda, et al.; J. Antibiot. 60, 321 (2007)
- Chemoenzymatic total synthesis of the antiproliferative polyketide (+)-(R)-aureothin: M. Werneburg & C. Hertweck; Chembiochem 9, 2064 (2008)
- Selective and potent in vitro antitrypanosomal activities of ten microbial metabolites: K. Otoguro, et al.; J. Antibiot. 61, 372 (2008)
- Natural lipophilic inhibitors of mitochondrial complex I are candidate toxins for sporadic neurodegenerative tau pathologies: M. Höllerhagen, et al.; Exp. Neurol. 220, 133 (2009)
- Evolution of metabolic diversity in polyketide-derived pyrones: using the non-colinear Aureothin assembly line as a model system: B. Busch, et al.; Phytochemistry 70, 1833 (2009)
- Exploiting enzymatic promiscuity to engineer a focused library of highly selective antifungal and antiproliferative Aureothin analogues: M. Werneburg, et al.; J. Am. Chem. Soc. 132, 10407 (2010)
品牌介绍
Adipogen公司由三个子公司组成，分别是Adipogen,Inc.(韩国),AdipogenSA(瑞士)和 AdipogenCorporation(美国圣地亚哥)。总部设在美国，运营总部在瑞士利斯塔尔。Adipogen公司专门从事生命科学研究试剂的开发，如癌症、免疫、炎症、代谢疾病（糖尿病、肥胖）、干细胞和神经退行性疾病等领域。其重点关注开发创新优质的ELISA试剂盒。另外，也可提供抗体和蛋白产品，Adipogen拥有自己的化学实验室，致力于开发创新型小分子化合物。
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