Adipogen/Astaxanthin/AG-CN2-0055-M005/5 mg
商品编号：
AG-CN2-0055-M005
品牌：
Adipogen Inc
市场价：
¥1000.00
美元价：
600.00
产品分类：
其他试剂
公司分类：
Other_reagents
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
| ProductDetails | |
|---|---|
| Synonyms | 3,3"-Dihydroxy-β-carotene-4,4"-dione;all-trans-Astaxanthin;Ovoester;NSC635689;CCRIS7118;HSDB7468 |
| ProductType | Chemical |
| Properties | |
| Formula | C40H52O4 |
| MW | 596.8 |
| CAS | 472-61-7 |
| Source/HostChemicals | Synthetic. |
| PurityChemicals | ≥97%(HPLC,NMR). |
| Appearance | Darkvioletredsolid. |
| Solubility | SolubleinDMSO,chloroformorDMF.Solubleinethanolormethanolifheated.Insolubleinwater. |
| Identity | Determinedby1H-NMR. |
| OtherProductData | Solubilityinaqueousbuffers:FurtherdilutionsoftheorganicsolventsolutionintoaqueousorisotonicsalineshouldbemadepriortoperformingBIOLOGicalexperiments.Storeaqueoussolutionsoniceandusewithin12hoursofpreparation.Itisstronglyrecommendedusingfreshperparationseachday. |
| InChiKey | MQZIGYBFDRPAKN-QISQUURKSA-N |
| ShippingandHandling | |
| Shipping | AMBIENT |
| ShortTermStorage | +4°C |
| LongTermStorage | -20°C |
| HandlingAdvice | Keepcoolanddry. |
| Use/StABIlity | Stableforatleast2yearsafterreceiptwhenstoredat-20°C. |
| Documents | |
| MSDS |  DownloadPDF |
| ProductSpecificationSheet | |
| Datasheet | DownloadPDF |
- Potentantioxidantcarotenoid[1].
- FreerADIcalscavenger[1,3].
- Reducesoxidativestress[1,3].
- Anticancercompound[2].
- Anti-inflammatory.BlocksNF-κBactivation[3,18].
- Anti-hypertensive.Cardiovascularprotective[4,6].
- Improvesneuronalstemcellpotential[7,9].
- Neuroprotective[10].
- Inhibitstumorinvasion[11].
- Apoptosisinducer[14].
- Increasesinsulinsensitivity[12].
- Attenuatesdiabetesassociatedcoagulatory,oxidativeandinflammatorystress[17].
- PPARαagoNISTandPPARγantagonist[19,20].
- Showspositiveeffectsonobesityandinsulinresistance[17,19,20]
- Hepatoprotective[21].
- Reviews[5,6,15,16].
ProductReferences
- Antioxidantactivitiesofastaxanthinandrelatedcarotenoids:Y.M.Naguib;J.Agric.FoodChem.48,1150(2000)
- Antitumoractivityofastaxanthinanditsmodeofaction:H.Jyonouchi,etal.;Nutr.Cancer36,59(2000)
- AstaxanthininhibitsnitricoxideproductionandinflammatorygeneexpressionbysuppressingI(kappa)Bkinase-dependentNF-kappaBactivation:S.J.Lee,etal.;Mol.Cells16,97(2003)
- Antihypertensivepotentialandmechanismofactionofastaxanthin:II.Vascularreactivityandhemorheologyinspontaneouslyhypertensiverats:G.Hussein,etal.;Biol.Pharm.Bull.28,967(2005)
- Astaxanthin:anovelpotentialtreatmentforoxidativestressandinflammationincardiovasculardisease:F.J.Pashkow,etal.;Am.J.Cardiol.101,58D(2008)(Review)
- Astaxanthin,oxidativestress,inflammationandcardiovasculardisease:R.G.Fassett&J.S.Coombes;FutureCardiol.5,333(2009)(Review)
- AstaxanthinImprovesStemCellPotencyviaanIncreaseintheProliferationofNeuralProgenitorCells:J.H.Kim,etal.;Int.J.Mol.Sci.11,5109(2010)
- Astaxanthindecreasedoxidativestressandinflammationandenhancedimmuneresponseinhumans:J.S.Park,etal.;Nutr.Metab.(Lond).7,18(2010)
- AstaxanthinimprovestheproliferativecapacityaswellastheosteogenicandAdipogenicdifferentiationpotentialinneuralstemcells:J.H.Kim,etal.;FoodChem.Toxicol.48,1741(2010)
- NeuroprotectiveeffectofastaxanthinonH(2)O(2)-inducedneurotoxicityinvitroandonfocalcerebralischemiainvivo:Y.P.Lu,etal.;BrainRes.1360,40(2010)
- AstaxanthininhibitstumorinvasionbydecreasingextracellularmatrixproductionandinducesapoptosisinexperimentalratcoloncarcinogenesisbymodulatingtheexpressionsofERK-2,NFkBandCOX-2:P.Nagendraprabhu&G.Sudhandiran;Invest.NewDrugs.29,207(2011)
- Highdoseastaxanthinlowersbloodpressureandincreasesinsulinsensitivityinrats:aretheseeffectsinterdependent?:H.G.Preuss,etal.;Int.J.Med.Sci.8,126(2011)
- Ameliorativeeffectofastaxanthinonendothelialdysfunctioninstreptozotocin-induceddiabetesinmalerats:Z.W.Zhao,etal.;Arzneimittelforschung61,239(2011)
- Astaxanthininducesmitochondria-mediatedapoptosisinrathepatocellularcarcinomaCBRH-7919cells:X.D.Song,etal.;Biol.Pharm.Bull.34,839(2011)
- Astaxanthin,cellmembranenutrientwithdiverseclinicalbenefitsandanti-agingpotential:P.Kidd;Altern.Med.Rev.16,355(2011)(Review)
- Astaxanthin:apotentialtherapeuticagentincardiovasculardisease:R.G.Fassett&J.S.Coombes;Mar.Drugs9,447(2011)(Review)
- Anticoagulatoryandantiinflammatoryeffectsofastaxanthinindiabeticrats:K.C.Chan,etal.;J.FoodSci.77,H76(2012)
- AstaxanthinTreatmentReducedOxidativeInducedPro-InflammatoryCytokinesSecretioninU937:SHP-1asaNovelBiologicalTarget:L.Speranza,etal.;Mar.Drugs10,890(2012)
- Thenaturalcarotenoidastaxanthin,aPPAR-aagonistandPPAR-gantagonist,reduceshepaticlipidaccumulationbyrewiringthetranscriptomeinlipid-loadedhepatocytes:Y.Jai,etal.;Mol.Nutr.FoodRes.56,878(2012)
- Astaxanthinfunctionsdifferentlyasaselectiveperoxisomeproliferator-activatedreceptorgmodulatorinadipocytesandmacrophages:M.Inoue,etal.;Biochem.Pharmacol.84,692(2012)
- Hepatoprotectivepotentialofastaxanthinagainst2,3,7,8-tetrachlorodibenzo-p-dioxininculturedrathepatocytes:H.Turkez,etal.;Toxicol.Ind.Health.30,101(2012)
品牌介绍
Adipogen公司由三个子公司组成，分别是Adipogen,Inc.(韩国),AdipogenSA(瑞士)和 AdipogenCorporation(美国圣地亚哥)。总部设在美国，运营总部在瑞士利斯塔尔。Adipogen公司专门从事生命科学研究试剂的开发，如癌症、免疫、炎症、代谢疾病（糖尿病、肥胖）、干细胞和神经退行性疾病等领域。其重点关注开发创新优质的ELISA试剂盒。另外，也可提供抗体和蛋白产品，Adipogen拥有自己的化学实验室，致力于开发创新型小分子化合物。
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