Adipogen/Asiaticoside/AG-CN2-0080-M010/10 mg
商品编号：
AG-CN2-0080-M010
品牌：
Adipogen Inc
市场价：
¥1200.00
美元价：
720.00
产品分类：
其他试剂
公司分类：
Other_reagents
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
| ProductDetails | |
|---|---|
| Synonyms | Blastostimulina;Centelase;Emdecassol;Madecassol;Marticassol;FK1080;BRN0078195;NSC166062 |
| ProductType | Chemical |
| Properties | |
| Formula | C48H78O19 |
| MW | 959.1 |
| CAS | 16830-15-2 |
| RTECS | YU9625000 |
| Source/HostChemicals | IsolatedfromCentellaasiatica. |
| PurityChemicals | ≥95%(NMR) |
| Appearance | Whitesolid. |
| Solubility | Solubleinethanol,methanolorpyridine.Insolubleinwater. |
| Identity | Determinedby1H-NMRand13C-NMR. |
| InChiKey | WYQVAPGDARQUBT-NXDSUYQXBS |
| ShippingandHandling | |
| Shipping | AMBIENT |
| ShortTermStorage | +4°C |
| LongTermStorage | +4°C |
| HandlingAdvice | Keepcoolanddry. |
| Use/StABIlity | Stableforatleast2yearsafterreceiptwhenstoredat+4°C. |
| Documents | |
| MSDS |  DownloadPDF |
| ProductSpecificationSheet | |
| Datasheet | DownloadPDF |
- Antibacterial.
- HumancollagenIsynthesisinducer.Anti-wrinkleactivity.
- Showswoundhealingactivity.Enhancesnormalhumanskincellmigration,attachmentandgrowth.
- SuppressescollagenexpressionandTGF-β/SmadsignalingbyinducingSmad7andinhibitingTGF-βRIandTGF-βRII.
- Anti-inflammatory.Anti-gastriculcer.
- Mitogen-activatedproteinkinases(MAPKs),nuclearfactor-κB(NF-κB),cyclooxygenase-2(COX-2)andinducIBLenitricoxidesynthase(iNOS;NOSII)expression,productionofserumtumornecrosisfactor(TNF-α)andinterleukin-6(IL-6)inhibitor.
- Apoptosisinducerincancercells.Enhancesantitumoractivityofvincristineincancercells.Mightbeusefulincancerchemotherapy.
- Anxiolytic.
- Antidepressant-likeactivity.
- Hepatoprotectiveeffects.
- CYP2C19andCYP3A4inhibitor.
- Neuroprotective.
- Antileishmanialactivity.
- cPLA2andsPLA2inhibitor.
ProductReferences
- InvitroandinvivowoundhealingactivityofasiaticosideisolatedfromCentellaasiatica:A.Shukla,etal.;J.Ethnopharmacol.65,1(1999)
- InvitrokeratinocyteantiproliferanteffectofCentellaasiaticaextractandtriterpenoidsaponins:J.H.Sampson,etal.;Phytomedicine8,230(2001)
- ThehealingeffectsofCentellaextractandasiaticosideonaceticacidinducedgastriculcersinrats:C.L.Cheng,etal.;LifeSci.74,2237(2004)
- InhibitoryeffectsofCentellaasiaticawaterextractandasiaticosideoninduciblenitricoxidesynthaseduringgastriculcerhealinginrats:J.S.Guo,etal.;PlantaMed.70,1150(2004)
- Improvinglipwrinkles:lipstick-relatedimageanalysis:J.S.Ryu,etal.;SkinRes.Technol.11,157(2005)
- AsiaticosideinduceshumancollagenIsynthesisthroughTGFbetareceptorIkinase(TbetaRIkinase)-independentSmadsignaling:J.Lee,etal.;PlantaMed.72,324(2006)
- Anxiolytic-likeeffectofasiaticosideinmice:S.W.Chen,etal.;Pharmacol.Biochem.Behav.85,339(2006)
- EffectsofasiaticosideontheexpressionofSmadproteinbynormalskinfibroblastsandhypertrophicscarfibroblasts:S.H.Qi,etal.;Clin.Exp.Dermatol.33,171(2008)
- Antidepressant-likeeffectofasiaticosideinmice:X.Liang,etal.;Pharmacol.Biochem.Behav.89,444(2008)
- ProtectiveeffectsofAsiaticosideonacuteliverinjuryinducedbylipopolysaccharide/D-galactosamineinmice:L.Zhang,etal.;Phytomedicine17,811(2010)
- AsiaticosidesuppressescollagenexpressionandTGF-β/SmadsignalingthroughinducingSmad7andinhibitingTGF-βRIandTGF-βRIIinkeloidfibroblasts:B.Tang,etal.;Arch.Dermatol.Res.303,563(2011)
- InvitroinhibitoryeffectsofasiaticosideandmadecassosideonhumancytochromeP450:T.Winitthana,etal.;Toxicol.InVitro25,890(2011)
- Asiaticoside:attenuationofneurotoxicityinducedbyMPTPinaratmodelofParkinsonismviamaintainingredoxbalanceandup-regulatingtheratioofBcl-2/Bax:C.L.Xu,etal.;Pharmacol.Biochem.Behav.100,413(2012)
- Asiaticosideinducestumour-necrosis-factor-α-mediatednitricoxideproductiontocureexperimentalvisceralleishmaniasiscausedbyantimony-susceptibleand-resistantLeishmaniadonovanistrains:S.K.Bhaumik,etal.;J.Antimicrob.Chemother.67,910(2012)
- InhibitionofcPLA2andsPLA2activitiesinprimaryculturesofratcorticalneuronsbyCentellaasiaticawaterextract:P.P.Defillipo,etal.;Nat.Prod.Commun.7,841(2012)
- Asiaticosideenhancesnormalhumanskincellmigration,attachmentandgrowthinvitrowoundhealingmodel:J.H.Lee,etal.;Phytomedicine19,1223(2012)
- AntipyreticandAnti-inflammatoryEffectsofAsiaticosideinLipopolysaccharide-treatedRatthroughUp-regulationofHemeOxygenase-1:J.Wan,etal.;Phytother.Res.27,1136(2013)
品牌介绍
Adipogen公司由三个子公司组成，分别是Adipogen,Inc.(韩国),AdipogenSA(瑞士)和 AdipogenCorporation(美国圣地亚哥)。总部设在美国，运营总部在瑞士利斯塔尔。Adipogen公司专门从事生命科学研究试剂的开发，如癌症、免疫、炎症、代谢疾病（糖尿病、肥胖）、干细胞和神经退行性疾病等领域。其重点关注开发创新优质的ELISA试剂盒。另外，也可提供抗体和蛋白产品，Adipogen拥有自己的化学实验室，致力于开发创新型小分子化合物。
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